Iowa State Cyclones vs Byu Cougars Picks and Predictions October 25th 2025

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BYU Cougars vs Iowa State Cyclones Game Preview

The BYU Cougars travel to face the Iowa State Cyclones on Saturday, October 25, 2025, at Jack Trice Stadium in Ames, Iowa. Kickoff is set for 3:30 PM ET on FOX.

No. 11 BYU (7-0, 4-0 Big 12) looks to remain unbeaten behind freshman sensation Bear Bachmeier, while Iowa State (5-2, 2-2 Big 12) seeks redemption at home after back-to-back conference losses. Both teams are fighting for Big 12 positioning as November approaches.

Keep track of real-time odds and results at the college football odds and scores page.

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Line Movement and Betting Odds

BYU Moneyline: +118
Iowa State Moneyline: -142
BYU Spread: +2.5 (-110)
Iowa State Spread: -2.5 (-110)
Total Over/Under: 49.5 (-110)

Oddsmakers expect a close battle between BYU’s power-run offense and Iowa State’s balanced attack. The total has remained steady at 49.5 points, reflecting both teams’ defensive capabilities and methodical pace.

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BYU Cougars

BYU continues to rise under coach Kalani Sitake, entering this matchup undefeated and ranked No. 11 nationally. The Cougars’ offense is anchored by quarterback Bear Bachmeier, who has thrown for 1,386 yards and nine touchdowns while rushing for eight more scores.

Running back LJ Martin has been the heartbeat of BYU’s offense, ranking fourth nationally with 774 rushing yards. Together, the pair power a ground game that ranks 10th in the country at 232.9 yards per contest.

The Cougars’ defense complements their physical style, forcing nine interceptions and tallying 13 sacks through seven games. Their 24-21 win over Utah last week showcased their ability to close out tight games, and they’ll now aim for their first-ever win over Iowa State (0-5 all-time).

Injury Report

Choé Bryant-Strother (LB) – Questionable (Undisclosed)
Raider Damuni (S) – Questionable (Undisclosed)
Marcus McKenzie (CB) – Questionable (Undisclosed)
Jojo Phillips (WR) – Questionable (Undisclosed)
Tommy Prassas (S) – Questionable (Undisclosed)
Sione Moa (RB) – Questionable (Undisclosed)

Full injury report for BYU Cougars

Iowa State Cyclones

Iowa State returns home after a bye week, eager to rebound from a 24-17 loss at Colorado. The extra preparation allowed running back Carson Hansen to clear concussion protocol, giving the Cyclones their two-headed backfield alongside Abu Sama III, who rushed for 177 yards and two touchdowns against the Buffaloes.

When both backs receive at least 10 carries, Iowa State is 3-0 this season. That formula helps ease the burden on quarterback Rocco Becht, who has thrown for 1,622 yards, nine touchdowns, and just three interceptions.

Defensively, Iowa State faces a major test in stopping BYU’s run game. The potential absence of standout tackle Domonique Orange could complicate matters, but the Cyclones have been resilient at home — posting a 4-0 record at Jack Trice Stadium this season.

Injury Report

Daniel Jackson (WR) – Questionable (Undisclosed)
Jontez Williams (DB) – Out (Undisclosed)
Eddie Lemos (DB) – Questionable (Undisclosed)
Deylin Hasert (OL) – Questionable (Undisclosed)
Jace T. Gilbert (K) – Questionable (Undisclosed)
Jeremiah Cooper (DB) – Questionable (Undisclosed)
Carson Hansen (RB) – Questionable (Concussion)
Michael Parkes (WR) – Questionable (Undisclosed)
Nick Reinicke (LB) – Questionable (Undisclosed)
Khijohnn Cummings-Coleman (DB) – Questionable (Undisclosed)

Full injury report for Iowa State Cyclones

Key Storylines

• BYU is off to a 7-0 start behind freshman QB Bear Bachmeier’s dual-threat efficiency.
• Iowa State has not lost at home this season (4-0).
• The Cyclones are 3-0 when both Carson Hansen and Abu Sama III record 10+ carries.
• BYU’s rushing offense ranks 10th nationally at 232.9 yards per game.
• Iowa State leads the all-time series 5-0, last winning 45-13 in 2023.

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Prediction

This matchup features two physical teams with contrasting offensive styles. BYU’s dominant rushing attack will test Iowa State’s front, especially if Domonique Orange remains sidelined. However, the Cyclones’ home-field advantage and balanced offense make them a live favorite.

Projected Score: Iowa State 27, BYU 23
Best Bet: Iowa State -2.5 (-110)
Secondary Lean: Under 49.5 (-110)

Stay updated with Big 12 betting results and model predictions at ScoresAndStats College Football.

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