Oklahoma Sooners vs Auburn Tigers Picks and Predictions September 20th 2025

Oklahoma Sooners vs Auburn Tigers September 20th 2025

The Auburn Tigers are set to take on the Oklahoma Sooners in Week 4 of the 2025 regular season. This game will be held at Memorial Stadium in Norman, Oklahoma. Both teams enter the game with a perfect 3-0 record this season.

The Tigers, ranked #22 in the AP Poll, are looking to continue their winning streak. The Sooners, ranked #11, will defend their home turf. Fans can catch the action live on ABC at 3:30 PM on Saturday, September 20, 2025.

Auburn vs Oklahoma CFB Key Information

• Sport: College Football
• Teams: Auburn Tigers vs. Oklahoma Sooners
• Venue: Memorial Stadium, Norman, OK
• Date: Saturday, September 20, 2025
• Betting Odds: Auburn Moneyline +199, Oklahoma Moneyline -242, Auburn Spread +6.5 (-107), Oklahoma Spread -6.5 (-113), Total Over 47.5 (-113), Total Under 47.5 (-106)

No. 22 Auburn visits No. 11 Oklahoma in SEC opener

The Auburn Tigers look to stay unbeaten as they head to Norman to face the Oklahoma Sooners in a clash that features familiar faces and plenty of storylines. Jackson Arnold, Auburn’s starting quarterback, returns to face his former team in a matchup that will help set the tone in the SEC. Both programs enter 3-0, both boast dynamic quarterbacks, and both are looking to establish themselves as legitimate contenders.

Betting Odds and Trends

Auburn Can Win If…

The Auburn Tigers are leaning heavily on their rushing attack to stay perfect. Jeremiah Cobb has been the workhorse, racking up 314 rushing yards and four touchdowns through three games. Behind a line that has steadily improved, Auburn has piled up 732 rushing yards, ranking 12th nationally, and has the balance to control tempo against the Sooners.

Quarterback Jackson Arnold is another key factor. In his first three games with Auburn, he’s thrown for 501 yards and four touchdowns without an interception, while adding 192 rushing yards and four more scores. His dual-threat ability and efficiency give the Tigers the ability to extend drives and limit Oklahoma’s offensive opportunities.

On defense, Auburn has shown an ability to generate pressure and take the ball away. They rank 4th in sacks (11), 2nd in interceptions, and 4th in fumbles recovered. If the Tigers’ front seven can get to John Mateer and create short fields, Auburn has a clear path to the upset.

Oklahoma Can Win If…

The Oklahoma Sooners look like one of the most complete teams in the country through three games. John Mateer has flourished in his first season as starter, throwing for 944 yards and five touchdowns while rushing for 161 yards and four more scores. His leadership has elevated the Sooners’ offense and provided consistency that was missing last season.

Oklahoma’s balance is evident in their ground game as well. Tory Blaylock has emerged with 168 rushing yards and three touchdowns, while Deion Burks leads the receiving corps with 225 yards and two scores. With multiple playmakers across the board, the Sooners’ offense can spread Auburn’s defense thin and attack in multiple ways.

Defensively, Oklahoma has been dominant, ranking 5th in points allowed and 8th in sacks. Their unit has given up just 181 yards per game, placing them among the nation’s best. Even with star defensive end R Mason Thomas suspended for the first half after a targeting call last week, the Sooners’ front should create enough pressure to slow Auburn’s offense.

The Lean

Oklahoma is a 6.5-point home favorite, but Auburn’s ability to run the football and Jackson Arnold’s familiarity with the Sooners make this a tricky matchup. The Tigers have covered in five of their last seven as an underdog, and this game projects tightly. The model calls for Oklahoma 28, Auburn 24 — giving Auburn the lean at +6.5.

The total is set at 47.5, and both teams have shown the ability to score into the 30s. Auburn has averaged 31 points per game, while Oklahoma put up 42 last week against Temple. With playmakers on both sides, the projection is 52 points, making the over the recommended play.

Game Preview Recap

This game carries extra intrigue with Jackson Arnold facing the team he started for a year ago. Arnold transferred to Auburn after Oklahoma retooled its offense, and both programs have benefited from the changes. Arnold has been efficient and turnover-free at Auburn, while John Mateer has energized the Sooners with his dual-threat ability.

Auburn’s Hugh Freeze compared Arnold’s situation to his own experience coaching Liberty against his former Ole Miss program, noting the mental challenge of facing familiar faces. Freeze praised Mateer as the “go-to guy” for Oklahoma’s offense and acknowledged the difficulty of slowing down a team firing on all cylinders.

For Oklahoma, the defense has been the headline. The Sooners have allowed just one touchdown in three games and are suffocating opponents to the tune of under 200 yards per game. Even without R Mason Thomas in the first half, the front remains deep and dangerous.

The history favors the Sooners as well. Oklahoma has won both prior meetings with Auburn, including a 27-21 road win last season. This time, with both teams in the national rankings, the matchup feels like an early measuring stick in the SEC and one that will test Auburn’s ability to hang with the elite.