Purdue Boilermakers vs Rutgers Scarlet Knights Picks and Predictions October 25th 2025

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Rutgers Scarlet Knights vs Purdue Boilermakers Game Preview

The Rutgers Scarlet Knights travel to West Lafayette to face the Purdue Boilermakers on Saturday, October 25, 2025, in a Big Ten showdown between two teams searching for their first conference victory. Kickoff is set for 3:30 PM ET at Ross-Ade Stadium.

Rutgers enters at 3-4 overall (0-4 Big Ten) after a tough 56-10 loss to Oregon, its fourth straight defeat. The Scarlet Knights have struggled defensively, allowing over 30 points per game, but coach Greg Schiano insists internal adjustments are underway to tighten the unit.

Purdue (2-5, 0-4 Big Ten) has dropped five consecutive games, most recently a 19-0 shutout loss at Northwestern. The Boilermakers could be without starting quarterback Ryan Browne, who suffered a shoulder injury last week.

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Line Movement and Betting Odds

Rutgers Moneyline: +142
Purdue Moneyline: -168
Rutgers Spread: +3.0 (-110)
Purdue Spread: -3.0 (-110)
Total Over/Under: 49.5 (-110)

Purdue opened as a narrow home favorite, but uncertainty surrounding quarterback Ryan Browne has drawn attention to the underdog Scarlet Knights. Bettors anticipate a lower-scoring affair given both teams’ offensive inconsistencies.

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Matchup Breakdown

Rutgers’ defense hit a low point in last week’s loss, giving up 750 total yards — including 415 rushing — to Oregon. Despite the setback, the Scarlet Knights have shown flashes of potential earlier in the season, forcing turnovers in four of their last six games. Quarterback Gavin Wimsatt leads the offense with 1,285 passing yards, seven touchdowns, and three rushing scores. Running back Samuel Brown V has added 524 rushing yards and five touchdowns, providing a reliable option in the backfield.

Purdue’s offensive identity has centered on dual-threat quarterback Ryan Browne, who has 1,572 passing yards, seven touchdowns, and four rushing scores. However, his shoulder injury places the Boilermakers’ game plan in flux. Backup Malachi Singleton showed competence in relief last week, throwing for 187 yards against Northwestern but struggled under pressure.

Defensively, Purdue remains a concern, ranking last in the Big Ten in total yards allowed (437.4 per game). The unit must find ways to contain Rutgers’ rushing attack and limit big plays early.

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Key Storylines

Both programs enter this matchup under pressure to reverse losing trends. Rutgers’ defensive adjustments will be critical after giving up 56 points to Oregon, while Purdue aims to end a 13-game Big Ten losing streak.

Greg Schiano has emphasized discipline and physicality as the Scarlet Knights’ foundation, but missed tackles and poor gap control have derailed recent performances. Purdue coach Barry Odom is dealing with his own issues — chiefly, quarterback health and pass protection after allowing nine sacks against Northwestern.

Whichever team can establish early rhythm offensively may seize momentum and escape the conference cellar.

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Injury Report

Rutgers Scarlet Knights:
Defensive lineman Aaron Lewis (ankle) is questionable, while cornerback Robert Longerbeam (hamstring) is also day-to-day. Linebacker Deion Jennings (shoulder) is expected to play.
Full injury report for Rutgers Scarlet Knights

Purdue Boilermakers:
Quarterback Ryan Browne (shoulder) is doubtful. Backup Malachi Singleton is expected to start if Browne cannot play. Wide receiver Deion Burks (undisclosed) and linebacker Clyde Washington (ankle) are questionable. Running back Tyrone Tracy Jr. (knee) remains out.
Full injury report for Purdue Boilermakers

Prediction

Both teams are desperate for momentum, but Rutgers’ improved ground game and Purdue’s quarterback uncertainty tilt the edge slightly toward the visitors. Expect a scrappy, low-scoring battle dominated by field position and turnovers.

Projected Score: Rutgers 24, Purdue 20
Best Bet: Rutgers +3.0 (-110)
Secondary Lean: Under 49.5 (-110)

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