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Syracuse vs UConn Picks and Predictions September 6th 2025
After a tough loss to a top-25 opponent, Syracuse looks to reset its season against UConn on Saturday. The Orange fell behind early to Tennessee in Week 1 and never recovered, ultimately losing 45-26. That wasn’t the season opener fans or players were hoping for.
Despite the loss, there were some positives. Notre Dame transfer Steve Angeli threw for a career-high 274 yards, showing promise under center. Running back Yasin Willis found the end zone three times, adding 91 yards on the ground. But Syracuse’s biggest issues were stopping the run and getting off the field on third down. Tennessee racked up 6.2 yards per carry and converted 7 of 12 third downs.
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Head coach Fran Brown made it clear this week that the team must approach this game with focus — but also with fun.
“We’re just ready to go out and have some fun,” Brown said. “There are no moral victories. We’re 0-1. But if we play with joy, we can bounce back.”
With Syracuse on a five-game win streak against UConn, the Orange hope the trend continues — especially in front of their home crowd.
UConn Confident After Statement Win
UConn enters the game with momentum after dismantling Central Connecticut 59-13 in Week 1. The Huskies executed well on both sides of the ball and flashed big-play potential. Skyler Bell’s 80-yard touchdown catch was a highlight, while quarterback Joe Fagnano tossed three TDs and added one more on the ground.
Running back Cam Edwards also stood out, rushing for 115 yards and a touchdown on just six carries.
While it was a dominant win, head coach Jim Mora Jr. emphasized the need to stay grounded.
“Every day is a new day,” Mora said. “Now we reset and focus on Syracuse. They’re a really good team, and we have to be sharp in all phases.”
If UConn wants to make this game competitive, they’ll need to pressure Angeli, contain Willis, and win the turnover battle.
Matchup Snapshot
| Team | Record | Week 1 Result | Key Performer |
|---|---|---|---|
| Syracuse | 0-1 | Lost 45-26 vs Tennessee | Yasin Willis: 91 yds, 3 TD |
| UConn | 1-0 | Won 59-13 vs Central Connecticut | Joe Fagnano: 3 Pass TD, 1 Rush TD |
Position-by-Position Comparison
| Unit | Edge |
|---|---|
| Quarterback | Syracuse – Angeli has more poise |
| Running Backs | Even – Willis and Edwards both strong |
| Wide Receivers | UConn – Bell adds explosive threat |
| Defensive Front | Syracuse – More pressure potential |
| Coaching | Even – Both Brown and Mora are motivators |
Best Bets and Predictions
Syracuse enters as a comfortable favorite but must tighten its defense. UConn has explosive potential and could make it interesting early. Expect the Orange to adjust and take control in the second half.
| Bet Type | Pick |
|---|---|
| Spread | UConn +21.5 |
| Total Points | Over 58.5 |
| Predicted Score | Syracuse 38, UConn 24 |
Need more insights? Explore expert betting guides and latest NCAAF odds before placing your bets.
FAQs
What happened in Syracuse’s opener?
They lost to Tennessee 45-26, falling behind 17-0 early and never fully recovering.
Who is Syracuse’s starting quarterback?
Steve Angeli, a transfer from Notre Dame, who threw for 274 yards in Week 1.
Did UConn look good in their opener?
Yes, they beat Central Connecticut 59-13 with a balanced offensive attack.
Is this a trap game for Syracuse?
It could be. UConn is confident and has playmakers, so Syracuse needs to be focused.
What’s the betting line?
Syracuse is favored by more than three touchdowns, but UConn is playing with confidence.
Where can I get more picks?
Check out college football picks for more expert analysis and betting tips.
