West Virginia Mountaineers vs Colorado Buffaloes Picks and Predictions November 8th 2025

West Virginia Mountaineers vs Colorado Buffaloes Football Sat, Nov 8, 12:00 pm.
West Virginia Mountaineers
ML: -250
29
22
Colorado Buffaloes
ML: 188
Last Updated on

West Virginia and Colorado share identical 3-6 records entering their Big 12 clash Saturday in Morgantown, W.Va., but the mood around the programs couldn’t be more different. The Mountaineers are trending up under Rich Rodriguez, while the Buffaloes are searching for answers as Deion Sanders turns to another freshman quarterback.

West Virginia rode a powerful ground game to a 45-35 win at then-No. 22 Houston, rushing for 246 yards to the Cougars’ 82. Freshman quarterback Scotty Fox Jr. accounted for two rushing scores and continues to settle in behind a physical offensive line. Bettors can explore more team stats and matchup data on the NCAA football previews page

Colorado, meanwhile, was hammered 52-17 by Arizona. Sanders rotated three quarterbacks before handing the starting job to 5-star freshman Julian Lewis, who hit a 59-yard touchdown in his debut. Sanders said the priority is getting Lewis comfortable: “He’s a young kid… He has to make quick reads and get the ball out.”

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Line Movement and Odds

The early line opened with West Virginia around –6.5 and a total near 55.5. As of midweek, odds have remained stable, showing balanced action between sharp and public money. See full updated numbers on the college football scores and odds page

West Virginia’s physicality and recent improvement at quarterback have drawn slight early money to the home side, while Colorado’s youth at QB keeps bettors cautious on the over. Those looking for real-time wagering edges can compare movement using our college football picks section

Matchup Breakdown

West Virginia outlook:
The Mountaineers’ run game is their identity. Diore Hubbard had 108 yards last week, and Fox Jr. added 65 and two scores. Their defense still allows big plays through the air, but at home they’ve held opponents to 21.8 points per game.

Colorado outlook:
The Buffaloes are 0-3 on the road and have struggled with turnovers, ranking near the bottom of the Big 12. Lewis’ athleticism gives them a spark, but protection remains a problem — Colorado has allowed 30 sacks this season.

For bettors seeking more matchup trends and handicapping angles, the expert betting guide breaks down how to read ATS momentum and pace statistics.

Injuries and Conditions

West Virginia

  • Out: QB Nicco Marchiol (ankle), WR Jaden Bray (hamstring)
  • Questionable: RB Clay Ash (foot)

Colorado

  • Out: CB Makari Vickers (shoulder), DL Amari McNeill (knee)
  • Questionable: WR Hykeem Williams (groin)

Full team updates are available on the West Virginia injury report and Colorado injury report

Weather in Morgantown should be mild and dry with light winds — ideal for an open passing game early before ground control takes over late.

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Best Bets and Prediction

West Virginia is 4-1 ATS in its last five home games as a favorite, while Colorado is 1-4 ATS on the road this year. Expect the Mountaineers to lean heavily on the run game and tempo. Projected score: West Virginia 31, Colorado 17.

Best Bet: West Virginia –6.5
Secondary Lean: Under 55.5

Looking for more guidance? Compare analysis on our Handicapper Leaderboard or review premium Service Plays from trusted experts. For new bettors, the Bettors Handbook covers bankroll tips and line-movement strategy.

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