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Denver Broncos vs New York Giants Betting Preview
The Denver Broncos look to continue their surge when they host the New York Giants in Week 7 of the NFL season. Kickoff is set for Sunday, October 19, 2025, at 4:05 PM ET from Empower Field at Mile High, airing on CBS.
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The Broncos (4-2) enter riding a three-game winning streak with victories over the Jets, Bengals, and Eagles — each fueled by dominant defensive performances. Meanwhile, the Giants (2-4) snapped their skid with an impressive 34-17 win over Philadelphia, showcasing renewed energy under young playmakers Jaxson Dart and Cam Skattebo.
Both teams are trending upward, but Denver’s defense — one of the NFL’s stingiest — presents a steep challenge for a Giants squad that’s winless on the road. Bettors can follow live updates and betting lines on the NFL scores and odds page for the latest movement throughout the week.
Line Movement and Odds
The Broncos opened as 7-point home favorites with a moneyline of -352, while the Giants sit at +281. The total for the game is set at 40.5 points (Over -105 / Under -115).
Denver’s strong defensive metrics and home dominance have pushed early money toward the favorite. The Broncos are undefeated at home this season (2-0) and have covered in five of their last six at Empower Field. New York, however, has been a sneaky cover team as an underdog, going 2-1 ATS in its past three.
For a breakdown of evolving line movements, visit the NFL expert betting guide for analysis on market shifts, public action, and consensus picks.
Matchup Breakdown
The Giants’ offense found new life under Jaxson Dart, who led the team to two wins in his first three starts. Against Philadelphia, Dart accounted for two touchdowns — one through the air and one on the ground — while Cam Skattebo powered the backfield with 98 rushing yards and three scores.
New York’s success lies in controlling tempo and avoiding turnovers. The Giants rank top five in fumble recoveries this season, and their young backfield duo has built a strong play-action rhythm. Still, facing Denver’s defense at altitude is no easy feat — especially for a team that’s 0-3 on the road.
Denver’s defense has been relentless, posting nine sacks last week against the Jets in London. Linebacker Nik Bonitto leads the NFL with eight sacks in six games, while safety Talanoa Hufanga anchors a secondary that’s forced six interceptions in as many weeks. The Broncos’ pass rush and discipline have been key to their 4-2 start.
Offensively, rookie quarterback Bo Nix has shown flashes of consistency, totaling nine touchdowns to four interceptions. His chemistry with Courtland Sutton and J.K. Dobbins gives the Broncos enough firepower to complement their elite defense.
To see how these defensive metrics influence postseason forecasts, check the Super Bowl odds and predictions blog for updated futures outlooks and division projections.
Injuries and Conditions
New York Giants:
Graham Gano (Groin) Out, Darius Slayton (Hamstring) Questionable, Micah McFadden (Lower Leg) Out, John Michael Schmitz Jr. (Concussion) Questionable, Victor Dimukeje (Pectoral) Out, Eric Gray (Knee) Out.
Denver Broncos:
Ben Powers (Biceps) Out, Dre Greenlaw (Quad) Out, Matt Peart (Knee) Out, Michael Burton (Hamstring) Out, Jonah Elliss (Ribs/Shoulder) Questionable, Drew Sanders (Foot) Out.
Both teams enter with key injuries, but Denver’s depth — particularly on defense — has helped offset personnel losses. For the Giants, losing veteran starters along the offensive line could be problematic against the Broncos’ aggressive front.
Best Bets and Prediction
The Broncos have established a clear identity — suffocating defense and efficient offense at home. Their ability to control field position and pressure quarterbacks should limit New York’s offensive rhythm. Meanwhile, the Giants’ promising rookies face their toughest test yet in a hostile Denver environment.
Projected Score: Broncos 24, Giants 14
Best Bet: Broncos -7 (-108)
Secondary Lean: Under 40.5 (-115)
Denver’s defense should dominate the trenches, and altitude could further slow the Giants’ offensive tempo. Expect the Broncos to cover comfortably behind a disciplined defensive effort and a controlled ground game.
Explore live props, ATS updates, and betting splits for this matchup on the NFL picks section — where you can track real-time market shifts and expert projections.
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Handicappers and Service Plays
See which experts are riding the Broncos or backing the spread on the ScoresAndStats best NFL handicappers leaderboard.
You can also follow premium analysis and top trends in the NFL expert betting guide, or stay ahead on futures markets with the Super Bowl odds and predictions blog.
