Philadelphia Eagles vs. Arizona Cardinals Pick & Prediction OCTOBER 9th 2022

Stadium: University of Phoenix Stadium Glendale
Logo Philadelphia Eagles
Logo Arizona Cardinals

48.5o -105
5.5 -110



The Philadelphia Eagles are arguably the best team in the NFL at the moment. They’re the only undefeated team in the league (4-0) and have been pretty dominant. Last week, they were down to the Jacksonville Jaguars, but rallied back and ended up winning 29-21.

The Arizona Cardinals are in an interesting spot at the moment. They’re 2-2, but there are still several questions surrounding the team. A win over the only undefeated team in the league would quiet the critics. The question is, can they pull off a win over the Eagles here?

Eagles vs. Cardinals Odds


MONEY LINE: Eagles (-240) vs. Cardinals (+198)

SPREAD: Eagles -5.5 (-106) vs. Cardinals +5.5 (-114)

GAME TOTAL: Over 48.5 (-115) vs. Under 48.5 (-105)

Eagles vs. Cardinals Preview (NFL Week 5)

Most people have likely already picked the Philadelphia Eagles to win this game. However, we’d recommend not being so hasty. The Eagles do several things well, but they’ve yet to face a mobile quarterback. Kyler Murray of the Arizona Cardinals presents a problem for Philadelphia.

As a defense, the Eagles allow 17.8 points per game, one of the better defenses in the league. Murray, however, won’t wait in the pocket for the Eagles pass rushers to get after him. Don’t be surprised if you see Murray scrambling for yards and potential touchdowns.

What we will say for the Eagles is their offense has looked incredible this season. Averaging 28.8 points per game, the Eagles rank fourth in the league. This week, they’re going against one of the worst defenses in the NFL. If they can get a solid lead, the Eagles should win this game.

The Arizona Cardinals defense ranks 28th in the league in points per game (25.8). Their poor performances this year on defense have led to a 2-2 record. Last week, they faced the Carolina Panthers and won the game 26-16. Before that, however, they lost at home to the LA Rams.

The key for the Cardinals in this game is to get a fast start. If they can get the Philadelphia defense on their heels, it’ll help their odds immensely. One thing they’ll absolutely have to do, however, is play much better defense. The question is, will they actually be able to?

Eagles vs. Cardinals Picks

Between these two teams, the Arizona Cardinals actually have a better record against the spread. The Eagles have gone 2-2 against the spread this season, while the Cardinals have gone 3-1.

We wouldn’t advise letting that be the only reason you take the Cardinals, however. We’re suggesting that the Cardinals might not win, but they will cover the spread. They have an offense that can keep up with the Eagles and a QB that’s willing to escape the pocket. Remember, the Detroit Lions only lost by three points to the Eagles in week 1.

Final Score: 24-20 (Eagles)


1. Philadelphia is 0-5 against the spread in their last five games when playing on the road against Arizona.

2. The Philadelphia Eagles have gone 4-1 in their last five games on the road.

3. The total has gone UNDER in six of Arizona's last nine games.

Best Bet: Cardinals +5.5 (-114) and Under 48.5 (-105)

Philadelphia Eagles
Arizona Cardinals