Los Angeles Chargers vs Philadelphia Eagles Picks and Predictions December 8th 2025

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Match Facts

MatchupDetail
GamePhiladelphia Eagles at Los Angeles Chargers
Week14 – 2025 NFL regular season
DateMonday, December 8, 2025 – 8:15 PM ET
VenueSoFi Stadium, Inglewood, CA (indoor, no weather factor)
RecordsEagles 8-4 (4-2 road), Chargers 8-4 (5-2 home)
CoachesEagles: Nick Sirianni; Chargers: Jim Harbaugh
Last meetingEagles 26, Chargers 24 (2017)
ContextKey playoff positioning game between two 8-4 teams in crowded NFC/AFC races

Line and Odds

  • Point spread: Eagles -3.0 (-104), Chargers +3.0 (-117)
  • Moneyline: Eagles -155, Chargers +130
  • Total: 40.5 (Over -114, Under -107)
  • Market read: Short road favorite at a relatively low total, signaling respect for both defenses and baked-in uncertainty on Justin Herbert’s hand
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Indianapolis Colts

Movement Matchup

The number is in the classic “respect both sides” pocket. Philadelphia is still priced as the slightly better team, even on the road, based on roster quality, coaching continuity and a strong track record against the spread over the last two seasons. At the same time, the market refuses to push the Eagles beyond a field goal because they are coming off back-to-back losses and have a serious fourth-quarter problem. They have been outscored 24-6 in the final frame over the last two games and 84-56 in the fourth quarter on the season. That kind of late-game collapse pattern keeps bettors from treating them like a fully reliable contender.

For the Chargers, the story is tied directly to Herbert. He fractured his non-throwing hand against the Raiders, had a plate and multiple screws inserted, and returned to limited practice almost immediately. He has made it clear he will play if the medical staff signs off, and offensive coordinator Greg Roman has been openly optimistic he will start. The current spread essentially assumes a compromised but active Herbert, not a full-strength version and not a total absence.

If Herbert were ruled out and Trey Lance named the starter, you would expect this number to jump toward Philadelphia and likely blow past the key of -3. If reports grow even more positive about Herbert’s comfort, ball security and ability to take hits, Chargers money could shave this down closer to -2.5 or lower. For now, at Eagles -3 and total 40.5, this sits as a fair midpoint that forces you to pick a side rather than offering obvious value either way. It is exactly the kind of game that shows up front and center on the NFL scores and odds screen: tight spread, high-profile teams, and a quarterback health storyline.

Breakdown Injury Reports

Philadelphia Eagles

PlayerStatusInjury
Lane Johnson (OT)OutFoot
Jalen Carter (DT)OutShoulder procedures
Charley Hughlett (LS)OutUndisclosed
Ogbo Okoronkwo (OLB)OutTriceps
Azeez Ojulari (OLB)OutHamstring
Johnny Wilson (WR)OutKnee/ankle
Ben VanSumeren (FB)OutKnee
Cameron Williams (OT)OutShoulder
Andrew Mukuba (S)OutAnkle
Marcus Epps (S)QuestionableUndisclosed
Xavier Gipson (WR)QuestionableShoulder
Myles Hinton (OT)QuestionableUndisclosed
Zack Baun (LB)Limited earlier in weekHand
Jaelan Phillips (LB)Limited earlier in weekConcussion
Jahan Dotson (WR)Limited earlier in weekToe

The two headline absences are obvious. Without Lane Johnson, the Eagles lose their best pass protector and a key edge run blocker, which matters a lot against a defense that gets home as well as the Chargers. Without Jalen Carter, they lose the most disruptive interior rusher on the roster, which lowers the ceiling of their pass rush and takes away a player who can wreck a drive by himself. Cluster issues at tackle and in the secondary could become a problem if this turns into a pass-heavy script on both sides.

Los Angeles Chargers

PlayerStatusInjury
Justin Herbert (QB)QuestionableFractured left hand (post-surgery with plate and screws)
Najee Harris (RB)OutAchilles
Rashawn Slater (OT)OutKnee
Joe Alt (OT)OutAnkle
Hassan Haskins (RB)OutHamstring
Junior Colson (LB)OutShoulder
Josh Fuga (DL)OutUndisclosed
Jordan Oladokun (DB)OutUndisclosed
Eric Rogers (DB)OutUndisclosed
Savion Washington (OL)OutUndisclosed
Otito Ogbonnia (DL)QuestionableElbow
Omarion Hampton (RB)QuestionableAnkle
Da’Shawn Hand (DL)DNP earlier in weekIllness
Tucker Fisk (TE)DNP earlier in weekAnkle

Herbert’s status is the pivot point, but the offensive line is just as concerning. Both Rashawn Slater and Joe Alt are out, which means the Chargers are going into this matchup with a patched-up tackle situation against a physical front. Even if Herbert plays, that combination raises pressure rates and increases the chance of hits on a quarterback playing with metal hardware in his hand. With Harris and Haskins out and Hampton banged up, the backfield depth is also stretched, placing more responsibility on Kimani Vidal to carry the load.

Philadelphia Eagles recent performance

Philadelphia is in a strange spot where the record still says “contender” and the tape says “sloppy closer.” The Eagles are 8-4 and still on top of the NFC East, but their last two outings—losses to Dallas and Chicago—have highlighted just how shaky they have become late in games. Across those two defeats, they have been outscored 24-6 in the fourth quarter, and the full-season fourth-quarter margin of 84-56 against them is not a small-sample fluke.

The high-end talent is still very real. Against the Bears, A.J. Brown erupted for 132 receiving yards and two touchdowns, showing again that he can flip a game by himself when the protection holds. Jalen Hurts threw for 230 yards and those two scores, and the passing game still looks fully capable of putting up tournament-level numbers when the timing is right. The run game remains a backbone; a year ago the Eagles were second in the league with 3,048 rushing yards, and Saquon Barkley has already stacked up 740 yards on the ground this season. When they are on schedule and committed to their identity, this is still a physically dominant offense.

Defensively, the group that finished second in opponent scoring last year has not disappeared. Even without Carter, there is size and power up front and enough speed at linebacker to disrupt opponents. The problem has been consistency across four quarters rather than talent. Nick Sirianni has admitted that some of the answers are not simple and has stressed that the fix is about regaining confidence and rhythm, not tearing up the scheme. Hurts has kept the locker room messaging on accountability and opportunity rather than panic. That steady tone is part of why the Eagles still grade out well when you compare them on the NFL teams page and in long-range futures conversations.

Los Angeles Chargers recent performance

The Chargers are starting to look like the team they expected to be under Jim Harbaugh: physical, balanced and prepared to win different types of games. They come in at 8-4 overall and 5-2 at home, with their latest showing a 31-14 handling of the Raiders at SoFi Stadium. In that game, Kimani Vidal led the way with 126 rushing yards and a touchdown, while Herbert chipped in 151 passing yards and two scores despite dealing with the hand injury.

Over the full season, this offense has been one of the best in football. The Chargers rank first in passing yards and first in scoring in their league. Herbert’s stat line—2,842 passing yards, 21 touchdowns, 10 interceptions—shows a quarterback still performing at a high level, and Greg Roman’s system has allowed them to lean on both the pass and the run depending on matchup. They can spread teams out and throw, or grind them down with a physical ground game when protecting a lead.

Defensively, they allow the fewest opponent scores and rank fifth in sacks. That combination of red-zone toughness and pass rush is exactly what you want against a quarterback like Hurts, who can be forced into rushed decisions when the pocket collapses. The big variable, of course, is Herbert’s hand and the state of the offensive line. A non-throwing-hand fracture is far from ideal, but it is not as catastrophic as an injury to the throwing arm; he has already played through it with protection and is back on the field in practice. If he is functional, the Chargers’ offensive profile does not collapse, though Roman may lean more on quick game and the run to protect him.

From a trends standpoint, both teams have been profitable in the right spots. Philadelphia is 10-5 against the spread in regular-season games since 2024 and 5-2 ATS in their last seven road contests, which shows the market has not consistently overpriced them away from home. Even though this is a bounce-back situation rather than a “play on them after a win” angle, it still speaks to the Eagles traveling well.

The Chargers, meanwhile, are perfect at home this season both straight-up and against the number, sitting at 3-0 in each category. They are also 4-0 straight-up in regular-season games with totals of 42 or less, which fits this matchup’s current 40.5 number. That tells you they handle lower-total, more tactical games well and have been able to control pace and game flow in those spots.

Matchup-wise, the tension is between Philadelphia’s structural edge and Los Angeles’ situational edge. The Eagles have the stronger roster on paper even with their injuries, plus the run game and explosive passing combo to stress any defense. The Chargers have the home field, the hotter offense right now and a defense that is built to attack a quarterback like Hurts. The question is whether Herbert’s compromised hand and a battered tackle group drag the Chargers down more than the Eagles’ fourth-quarter issues drag Philadelphia down. This is exactly the kind of read you build into your card when you’re scanning the main NFL picks board and ranking sides by confidence.

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Best Bets and Prediction

The most likely shape of this game is a controlled, physical contest that never fully bogs down but also never turns into a full-blown shootout. Both offenses have too much talent to sit in the teens for four quarters if the quarterbacks stay upright.

A realistic projection is Eagles 24, Chargers 20. That score respects the Chargers’ offensive balance and home form but accounts for the fact that Herbert is playing through a hand fracture behind a short-handed offensive line. In that scenario, the Eagles manage to generate just enough negative plays—sacks, holding calls, stalled drives—to hold Los Angeles a step behind while their own offense leans on Barkley’s ground work and Hurts–Brown explosives to get into the mid-twenties.

That kind of result lands on a clean Philadelphia cover at -3 and pushes the game over the 40.5 total without asking for an offensive explosion. You are not betting on the Eagles suddenly becoming flawless; you are betting that their structural advantages and their track record as a road ATS team outweigh their late-game sloppiness against a Chargers side carrying real injury risk in the most important position group on the field.

Handicapper section

From a handicapping perspective, this game boils down to which uncertainty you are more willing to live with. On one side, you have an Eagles team with a strong multi-year profile, a proven ceiling on both sides of the ball and a documented fourth-quarter issue that has cost them two straight games. On the other, you have a Chargers team that is playing very well, especially at home, with a high-powered offense and stingy defense but a quarterback with a surgically repaired hand behind a depleted offensive line.

If you trust Philadelphia’s longer-term profile more than you fear their recent slump, Eagles -3 is the logical side. Their road ATS record, their ability to dominate with the run when they commit to it, and their offensive firepower through Hurts and Brown all support laying a short number, even in a difficult environment. You are effectively wagering that coaching adjustments and urgency will clean up at least some of the late-game mess we have seen in recent weeks.

If you are more bullish on Herbert’s health and Harbaugh/Roman’s ability to hide the offensive line problems, then taking the points with the Chargers is defensible, especially if the number ever ticks up or a rogue +3.5 appears. Their perfect home record straight-up and against the spread, combined with their offensive and defensive rankings, show they are not a mirage.

Within a full Week 14 portfolio, this matchup is exactly the sort of game you fold into a broader strategy informed by the NFL expert betting guide and the futures picture shaped in part by pieces like the Super Bowl odds and predictions. The edge here is real but thin. Treat it as a high-quality piece of the card, not the entire foundation.

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