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Colorado Rockies vs San Diego Padres Picks and Predictions April 22nd 2026
The Padres and Rockies are back at Coors Field on Wednesday night, with first pitch set for 8:40 p.m. ET in Denver. San Diego comes in at 16-7 and second in the NL West, while Colorado is 9-15 and fifth after dropping Tuesday’s opener 1-0. The Padres have won three straight, and this is starting to feel like another spot where the better roster is trying to squeeze a divisional opponent before the market fully catches up. San Diego has been much steadier than Colorado in the early season sample, especially away from home. The Padres are 7-3 on the road, and even with an offense that has not fully clicked yet, they keep winning because the run prevention has
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Arizona Diamondbacks vs Chicago White Sox Picks and Predictions April 22nd 2026
The White Sox and Diamondbacks meet Wednesday night at Chase Field in Phoenix, with first pitch set for 9:40 p.m. ET on ARID and CHSN. Chicago comes in at 9-14 after blasting Arizona 11-5 on Tuesday, while the Diamondbacks are 13-10 and trying to keep this from turning into a bad home series against a team that came in struggling. Arizona still sits third in the NL West, and Chicago remains fourth in the AL Central, so this is one of those early-season games that matters a little more than it looks at first glance. The opener changed the tone of the matchup. The White Sox have now scored 33 runs over their last four games, and Munetaka Murakami has
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San Francisco Giants vs Los Angeles Dodgers Picks and Predictions April 22nd 2026
The Dodgers and Giants are back at Oracle Park on Wednesday night, with first pitch set for 9:45 p.m. ET in San Francisco. Los Angeles enters this one at 16-7, tied for first in the NL West, while San Francisco is 10-13 and sitting fourth after taking Tuesday’s opener 3-1. The broadcast is set for SportsNet LA and NBC Sports Bay Area. This matchup is still tilted toward Los Angeles because the bigger sample says the Dodgers have been the better club by a wide margin. They are 6-4 over their last 10, they lead the majors in runs among NL West teams shown here with a +55 run differential, and they have been one of the most explosive offenses
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Miami Marlins vs St. Louis Cardinals Picks and Predictions April 22nd 2026
The St. Louis Cardinals, who have won six of their past seven games, may be off to a surprising start to some, but not to manager Oliver Marmol. “It’s exactly what I would’ve anticipated this group to do,” Marmol said on Tuesday prior to a 5-3 Cardinals’ win over the host Miami Marlins. On Wednesday afternoon, both teams will try to take the three-game series. St. Louis has won back-to-back series while Miami hasn’t taken a series since winning two of three against the Chicago White Sox from March 30-April 1. The pitching matchup features a pair of right-handers, Miami’s Janson Junk (0-2, 4.50 ERA) against St. Louis’ Kyle Leahy (2-2, 5.21). Junk has never faced the Cardinals, and the
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San Jose Earthquakes vs Austin Fc Picks and Predictions April 22nd 2026
The San Jose Earthquakes are enjoying the best eight-match start in franchise history and coach Bruce Arena doesn’t want to hear any chatter about a letdown. The destructive Earthquakes (7-1-0, 21 points) have outscored opponents 17-3 and look to inflict more damage when they host Austin FC on Wednesday night. Austin FC (1-3-4, 7 points) is winless in their past six MLS matches (0-3-3). “There are no trap games in this league,” Arena told reporters. “Any team can beat you on a given day in this league. We understand that. It’s going to be a difficult game on Wednesday. We played Austin last year and I think we split with them. … It’s going to be a difficult game.” The

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Real Salt Lake vs Inter Miami Cf Picks and Predictions April 22nd 2026

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Inter Miami visits Real Salt Lake for second test following coaching change Inter Miami passed their first test since the surprise departure … more

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Edmonton Oilers vs Anaheim Ducks Picks and Predictions April 22nd 2026

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‘We’re right there’: Ducks hungry to even series with Oilers After feeling like they let a win slip from their grasp in … more

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Minnesota Wild vs Dallas Stars Picks and Predictions April 22nd 2026

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Wild’s Marcus Foligno: Stars ‘can’t hang with us 5-on-5’ entering G3 As far as Minnesota Wild forward Marcus Foligno is concerned, the … more

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Oklahoma City Thunder vs Phoenix-suns Picks and Predictions April 22nd 2026

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Thunder to read their ‘menu’ in anticipating Suns’ Game 2 adjustments Limited to just 33 games in the regular season by a … more

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Philadelphia Flyers vs Pittsburgh Penguins Picks and Predictions April 21st 2026

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Flyers return home in search of 3-0 lead over Penguins In a first-round playoff series between Pennsylvania rivals, the Philadelphia Flyers threw … more