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Lsu Tigers vs Western Kentucky Hilltoppers Picks and Predictions November 22nd 2025
The LSU Tigers return to Tiger Stadium on Saturday for their final nonconference game of the season as they host a Western Kentucky Hilltoppers team still firmly in the Conference USA championship race. LSU enters 6-4 after edging Arkansas 23-22 to earn bowl eligibility, while Western Kentucky arrives at 8-2 and sits one win away from securing a spot in the C-USA title game. The LSU Tigers turn to Michael Van Buren Jr. again with Garrett Nussmeier doubtful, and the Western Kentucky Hilltoppers look to continue their offensive surge behind Rodney Tisdale Jr. as they face their toughest road test yet. Oddsmakers opened LSU around -6.5 at home with a total near 58. It marks the Tigers’ third game under
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Stanford Cardinal vs California Golden Bears Picks and Predictions November 22nd 2025
Rivalry tradition returns to Northern California on Saturday as the California Golden Bears visit the Stanford Cardinal for the 128th edition of the Big Game. While Cal seeks to strengthen its bowl positioning at 6–4, Stanford looks for program momentum under interim coach Frank Reich, who hopes to etch his name among the coaching legends who have delivered rivalry wins for the Cardinal. This season introduced a new face to the rivalry: Reich, the former NFL head coach and Super Bowl–winning coordinator. Though his tenure is limited to a one-year interim arrangement, he has emphasized what this specific matchup means within the Stanford community. For the Cardinal, this serves as an opportunity to close the season with identity and purpose,
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South Carolina Gamecocks vs Coastal Carolina Chanticleers Picks and Predictions November 22nd 2025
South Carolina returns to Williams-Brice Stadium trying to regroup after one of the most painful collapses in program history. The South Carolina Gamecocks led 30–3 against No. 3 Texas A&M last weekend before surrendering 28 unanswered points in a 31–30 loss. The defeat extended their losing streak to five and marked another setback in a disappointing 3–7 season. Despite the collapse, head coach Shane Beamer praised his team’s response during Sunday’s practice and emphasized the importance of finishing the season strong. South Carolina now faces a dangerous foe in the Coastal Carolina Chanticleers, who arrive at 6–4 after scoring 40 or more points in four straight games before falling 45–40 at Georgia Southern. Coastal Carolina’s offense has surged over the
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Ucf Knights vs Oklahoma State Cowboys Picks and Predictions November 22nd 2025
Two struggling programs meet Saturday in Orlando as the UCF Knights host the Oklahoma State Cowboys in a matchup featuring two teams desperate to stop prolonged losing streaks. Across the last eight weeks, the Knights and Cowboys have combined for just one win, with both offenses sputtering and both defenses collapsing under workload and inconsistency. Oklahoma State enters at 1–9, having fired longtime head coach Mike Gundy in September after the program’s worst start in decades. Interim coach Doug Meacham has seen flashes of progress — including last week’s tight game at Kansas State — but turnovers and late-game inefficiency continue to bury the Cowboys. Their loss to Kansas State featured two interceptions from quarterback Zane Flores, including a critical
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North Carolina Tar Heels vs Duke Blue Devils Picks and Predictions November 22nd 2025
Duke and North Carolina enter Saturday’s rivalry meeting with urgency, frustration and postseason implications converging on a single stage. The Duke Blue Devils are looking to rebound after falling out of ACC title contention, while the North Carolina Tar Heels cling to their last opportunity to stay in the bowl race at 4–6. The Victory Bell adds another layer of intensity to a matchup already defined by regional familiarity. Duke coach Manny Diaz emphasized that redemption in sports is always “a week away,” referencing the need to reset after a 34–17 loss to Virginia. For North Carolina, first-year head coach Bill Belichick prepares for his debut in this rivalry, acknowledging its local significance. Duke enters at 5–5, 4–2 in ACC

College football promo graphic featuring UCLA Bruins and Washington Huskies players with team logos and Scores and Stats branding, promoting betting picks and predictions for their November 22, 2025 matchup.

Ucla Bruins vs Washington Huskies Picks and Predictions November 22nd 2025

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Game Preview: Washington Huskies @ UCLA Bruins Two long-time Pac-12 foes meet again under the Big Ten banner when the Washington Huskies … more

College basketball promo graphic featuring Texas A&M Aggies and Manhattan Jaspers players with team logos and Scores and Stats branding, promoting betting picks and predictions for their November 21, 2025 matchup.

Lsu Tigers vs Omaha Mavericks Picks and Predictions November 21st 2025

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Game Preview: LSU Tigers @ Omaha Mavericks The LSU Tigers return to the Pete Maravich Assembly Center on Friday looking to extend … more

College basketball promo graphic featuring Texas A&M Aggies and Manhattan Jaspers players with team logos and Scores and Stats branding, highlighting betting picks and predictions for their November 21, 2025 matchup.

Texas A&m Aggies vs Manhattan Jaspers Picks and Predictions November 21st 2025

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Game Preview: Texas A&M @ Manhattan Texas A&M returns to Reed Arena looking to stack back-to-back wins when it hosts Manhattan in … more

GAME PREVIEW Cincinnati Bearcats vs Louisville Cardinals

Cincinnati Bearcats vs Louisville Cardinals Picks and Predictions November 21st 2025

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Game Preview Louisville Cardinals @ Cincinnati Bearcats Louisville has surged into the national spotlight with a 4–0 start, climbing to No. 6 … more

GAME PREVIEW Florida Gators vs Merrimack Warriors

Florida Gators vs Merrimack Warriors Picks and Predictions November 21st 2025

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Game Preview Florida Gators @ Merrimack Warriors Florida returns home carrying consecutive wins over in-state rivals and enters the matchup with the … more