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The San Francisco Giants visit the Philadelphia Phillies on Wednesday, April 29, 2026, at Citizens Bank Park in Philadelphia. First pitch is set for 6:40 PM ET, with coverage listed on NBCS. San Francisco comes in at 13-16 and fourth in the NL West, while Philadelphia sits 10-19 and fourth in the NL East. The Phillies took the opener 7-0 on Tuesday, snapping some of the pressure around a rough April and giving them a needed reset at home. San Francisco has still played better baseball over the last 10 games, going 6-4, but that lineup looked flat in the opener with only two hits. This matchup gets a stronger pitching feel with Logan Webb going for the Giants and

Nacional travel to face Universitario in Copa Libertadores Group B on Wednesday, April 29, 2026, at Estadio Monumental U Marathon in Lima. Kickoff is set for 10:00 PM ET, and this is already a pretty important group-stage spot because the table is starting to put pressure on the home side. Nacional enter the match top of Group B with four points from two matches. They drew away to Coquimbo Unido and then beat Deportes Tolima 3-1, so they have a real chance to take control of the group with another positive result. Universitario are bottom with one point after a 0-0 draw at Tolima and a 2-0 home loss to Coquimbo Unido. That makes the betting setup tricky. Universitario are

Flamengo travel to face Estudiantes de la Plata in Copa Libertadores Group A on Wednesday, April 29, 2026, at Estadio Jorge Luis Hirschi in La Plata. Kickoff is set for 8:30 PM ET, and this is a direct top-of-the-group matchup with real control of the section at stake. Flamengo enter first in Group A with six points from two matches, six goals scored, and just one allowed. Estudiantes are second with four points after drawing away to Independiente Medellín and beating Cusco FC at home. So, while Flamengo are the sharper team on recent form, Estudiantes are unbeaten in the group and can move top with a home win. The market leans Flamengo, which is fair. They are in excellent

Palmeiras travel to face Cerro Porteño in Copa Libertadores Group F on Wednesday, April 29, 2026, at Estadio General Pablo Rojas in Asunción. Kickoff is set for 8:30 PM ET, and this is a useful pressure spot because Palmeiras are trying to stay in control of the group, while Cerro Porteño need the home result to keep pace. Cerro are not in a bad position after beating Junior 1-0, but the margin for error is thin. They lost their opener to Sporting Cristal, and now they get the toughest opponent in the section. Palmeiras, meanwhile, have already taken points from both group matches and arrive in strong overall form. The market has Palmeiras as the favorite, which makes sense. Still,