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Pittsburgh Pirates vs San Diego Padres Picks and Predictions April 6th 2026
San Diego opens this series at PNC Park on Monday night, with first pitch set for 6:40 p.m. ET in Pittsburgh. The Padres come in 4-5 and third in the NL West after winning back-to-back games in Boston, while the Pirates are 6-3, third in the NL Central, and riding a five-game winning streak after sweeping Baltimore. Regional coverage is on SportsNet PT, with streaming also available via MLB.TV. The weather looks cold for early April, around 42 degrees at game time with a light breeze and little rain risk, which matters in a park that can already play a bit bigger at night. The pitching matchup is German Marquez against Bubba Chandler, and that is really where this handicap
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Miami Marlins vs Cincinnati Reds Picks and Predictions April 6th 2026
Cincinnati opens a four-game set at loanDepot Park on Monday night, with first pitch scheduled for 6:40 p.m. ET in Miami. Both clubs are 6-3, but they got there differently. The Reds just swept Texas on the road and allowed only four runs all weekend, while the Marlins had to survive a long rain delay and a late comeback to avoid a sweep against the Yankees on Sunday. Miami is 5-1 at home, Cincinnati is 3-0 on the road, and this feels like one of the tighter games on the board. There is also a little more context here than the surface records show. The Reds made the playoffs last season and have started this year by leaning on run
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Boston Red Sox vs Milwaukee Brewers Picks and Predictions April 6th 2026
Milwaukee opens a three-game set at Fenway Park on Monday night, with first pitch scheduled for 6:45 p.m. ET in Boston. The Brewers come in at 7-2, 2-1 on the road, and sitting on top of the NL Central. Boston is 2-7, 1-2 at home, and trying to stop another slide after dropping two straight to San Diego. The game is on NESN and Brewers.TV, and the weather looks chilly even by early-April standards, with game-time temperatures in the mid to upper 40s and a noticeable breeze. This is a pretty clean handicap on paper. Milwaukee has been the better offense, the steadier pitching staff, and the better overall team through the first nine games. The Brewers just took a
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Washington Nationals vs St. Louis Cardinals Picks and Predictions April 6th 2026
St. Louis opens a three-game set at Nationals Park on Monday night, with first pitch scheduled for 6:45 p.m. ET in Washington. The Cardinals come in 5-4 and fourth in the NL Central after salvaging the finale in Detroit, while the Nationals are 3-6, fifth in the NL East, and trying to stop a five-game slide after getting swept by the Dodgers. MLB.TV has the stream, and the weather looks playable with temperatures around the low 60s at first pitch, very little rain risk, and a light breeze around 10 mph. Andre Pallante gets the ball for St. Louis against Zack Littell for Washington. Pallante’s line is clean after his first outing, 1-0 with a 0.00 ERA, while Littell enters
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Toronto Blue Jays vs Los Angeles Dodgers Picks and Predictions April 6th 2026
Los Angeles opens a three-game set at Rogers Centre on Monday night, with first pitch scheduled for 7:07 p.m. ET in Toronto. The Dodgers come in 7-2, undefeated on the road at 3-0, and sitting atop the NL West after a weekend sweep in Washington. The Blue Jays are 4-5, second in the AL East, and trying to stop a four-game losing streak after getting swept at home by the White Sox. FS1 and MLB.TV have the broadcast for this one, and yes, it is the first meeting between these clubs since the Dodgers finished off last year’s World Series in Toronto. This matchup is interesting because the market is asking you to weigh the Dodgers’ obvious lineup edge against

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Alabama Crimson Tide vs. Eastern Kentucky Eastern Kentucky Pick & Prediction DECEMBER 23rd 2023

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Alabama needs to experience something good after a brutal stretch. The Crimson Tide might receive their wish Saturday afternoon as Eastern Kentucky … more

Villanova player, wearing jersey #21, caught in a moment of pure joy—possibly after a big play or a crucial win.

DePaul Blue Demons vs. Villanova Wildcats Pick & Prediction DECEMBER 23rd 2023

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DePaul opens Big East play Saturday afternoon with a tough task when they host a confident Villanova team in Chicago. DePaul (2-8, … more

Seton Hall player in a white jersey drives to the hoop for a layup against defenders.

Xavier Musketeers vs. Seton Hall Pirates Pick & Prediction DECEMBER 23rd 2023

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Seton Hall will attempt to build off one of its most impressive wins in program history when it travels to Cincinnati for … more

West Virginia Mountaineers player clapping hands during a college basketball game against Virginia Tech.

West Virginia Mountaineers vs. Toledo Toledo Pick & Prediction DECEMBER 23rd 2023

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After a stunning loss just a few days ago, West Virginia will dust itself off for a Saturday afternoon clash against Toledo … more

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NC State Wolfpack vs. Detroit Mercy Titans Pick & Prediction DECEMBER 23rd 2023

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There are some pretty solid feel-good elements for North Carolina State heading into the weekend. The Wolfpack are trying to build momentum … more