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Seattle Mariners vs Oakland Athletics Picks and Predictions April 22nd 2026
The Athletics need only to look to the top of the third deck in right field at T-Mobile Park to realize the road to the American League West title goes through Seattle. That’s where the Mariners’ 2025 division championship banner hangs. “(The Mariners) were one game away from going to the World Series last year,” the Athletics’ Shea Langeliers said. “Last year, it kind of felt like a dogfight every time we played them. I don’t think it’s going to be any different this year. These early games in the season, you can look back later and realize how much they mean.” Langeliers homered for a second consecutive night Tuesday, leading the A’s to a 5-2 victory as they remained
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Tampa Bay Rays vs Cincinnati Reds Picks and Predictions April 22nd 2026
Cincinnati goes for a sweep Wednesday afternoon at Tropicana Field, with first pitch set for 1:10 p.m. ET on MLB.TV. The Reds come in at 16-8, first in the NL Central, and they have been excellent away from home at 10-2. Tampa Bay is 12-11, second in the AL East, but only 4-4 at home and trying to stop a three-game slide. Even with the Rays still favored, this feels like one of those spots where recent form and price are pulling in opposite directions. The Reds have already taken the first two games of the series, winning 6-1 on Monday and 12-6 on Tuesday. Cincinnati has now won five straight and is chasing a perfect 6-0 road trip, while
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Cleveland Guardians vs Houston Astros Picks and Predictions April 22nd 2026
Houston heads into Progressive Field for Wednesday’s series finale trying to salvage a split after Tuesday’s 8-5 loss. The Astros are 9-16, last in the AL West, and just 2-10 on the road. Cleveland is 14-11, first in the AL Central, and 8-4 at home. First pitch is set for 1:10 p.m. ET, and the conditions look mild for an April afternoon in Cleveland, with temperatures around 60 degrees and only a light breeze. The game state matters here. Cleveland stole Tuesday’s win with a six-run eighth inning after trailing late, while Houston’s bullpen issues showed up again in a series where the Astros have already asked too much from the relief group. Even so, this is not a simple
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Kansas City Royals vs Baltimore Orioles Picks and Predictions April 22nd 2026
The Orioles and Royals wrap up their three-game set Wednesday afternoon at Kauffman Stadium, with first pitch scheduled for 2:10 p.m. ET. Baltimore comes in at 11-13, third in the AL East, while Kansas City is 8-16 and fifth in the AL Central. The series is tied 1-1 after the Royals stole Tuesday’s game 6-5 on a walk-off wild pitch, and that matters because both teams badly need a clean finish to the series after uneven starts. The recent form is not especially flattering for either side. The Orioles have lost six of their last eight and are 4-6 over their last 10, while the Royals just snapped an eight-game skid and are 2-8 over that same stretch. The weather
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Los Angeles Angels vs Toronto Blue Jays Picks and Predictions April 22nd 2026
The Blue Jays and Angels close out their series Wednesday afternoon at Angel Stadium, with first pitch set for 3:07 p.m. ET. Toronto comes in at 10-13, fourth in the AL East, and has a chance to finish a three-game sweep after taking the first two games 5-2 and 4-2. Los Angeles is 11-14, third in the AL West, and trying to stop a four-game slide. The stream is listed on MLB.TV, and the weather setup in Anaheim looks mild, with intervals of clouds and sun and temperatures in the low 70s. This is an interesting market because the Angels are still favored even though Toronto has won three straight overall and already handled this matchup twice in Anaheim. The

Boston Red Sox

Boston Red Sox vs Tampa Bay Rays Picks and Predictions May 16th 2024

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Red Sox vs. Rays: Game On for Series Showdown at Fenway As the Boston Red Sox prep to host the Tampa Bay … more

Houston Astros

Houston Astros vs Oakland Athletics Picks and Predictions May 16th 2024

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Astros Looking to Clean Sweep the A’s as Cristian Javier Steps Up Houston, TX — The Houston Astros are just a win … more

Cubs vs Pirates

Chi. Cubs Cubs vs Pittsburgh Pirates Picks and Predictions May 16th 2024

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Andrew McCutchen Aims to Stay Hot as Pirates Face Cubs Andrew McCutchen will attempt to keep turning back the clock on Thursday … more

Minnesota Timberwolves vs Denver Nuggets

Minnesota Timberwolves vs Denver Nuggets Picks and Predictions May 16th 2024

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Wolves Try to Corral Nuggets Star Nikola Jokic, Force Game 7 The Denver Nuggets are looking to wrap up their Western Conference … more

Carolina Hurricanes

Carolina Hurricanes vs Ny Rangers Rangers Picks and Predictions May 16th 2024

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Canes Stage Epic Comeback to Take Rangers to Game 6 Raleigh, N.C. — It’s crunch time! The Carolina Hurricanes have flipped the … more