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Tampa Bay Rays vs Chicago Cubs Picks and Predictions April 6th 2026
Chicago heads to St. Petersburg for Monday’s 4:10 p.m. ET first pitch at Tropicana Field, where both clubs enter 4-5 but with very different moods. The Cubs just split a Sunday doubleheader in Cleveland after Saturday’s rainout, while the Rays won two of three in Minnesota and now come home for their first regular-season game back at the Trop since Hurricane Milton damaged the stadium in October 2024. Monday’s opener is sold out, marking Tampa Bay’s 20th straight home opener sellout, and the game will air on Marquee Sports Network, Rays.TV, and WMOR. This matchup also has a little more texture than the records suggest. Jameson Taillon gets the ball for Chicago, Shane McClanahan starts for Tampa Bay, and the
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Cleveland Guardians vs Kansas City Royals Picks and Predictions April 6th 2026
Kansas City opens AL Central play Monday night at Progressive Field, with first pitch set for 6:10 p.m. ET in Cleveland. The Royals come in 4-5 after dropping the series finale to Milwaukee, while the Guardians are 6-4, leading the division after splitting Sunday’s doubleheader with the Cubs. The stream is on MLB.TV, and the market has Cleveland installed as a slight home favorite in a low-total game, which makes sense with Michael Wacha and Tanner Bibee getting the ball. The weather looks cold and a little unsettled, with temperatures in the mid-40s around first pitch and a chance of light showers during the evening. This is a pretty interesting opener because both teams can make a case. Kansas City
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Pittsburgh Pirates vs San Diego Padres Picks and Predictions April 6th 2026
San Diego opens this series at PNC Park on Monday night, with first pitch set for 6:40 p.m. ET in Pittsburgh. The Padres come in 4-5 and third in the NL West after winning back-to-back games in Boston, while the Pirates are 6-3, third in the NL Central, and riding a five-game winning streak after sweeping Baltimore. Regional coverage is on SportsNet PT, with streaming also available via MLB.TV. The weather looks cold for early April, around 42 degrees at game time with a light breeze and little rain risk, which matters in a park that can already play a bit bigger at night. The pitching matchup is German Marquez against Bubba Chandler, and that is really where this handicap
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Miami Marlins vs Cincinnati Reds Picks and Predictions April 6th 2026
Cincinnati opens a four-game set at loanDepot Park on Monday night, with first pitch scheduled for 6:40 p.m. ET in Miami. Both clubs are 6-3, but they got there differently. The Reds just swept Texas on the road and allowed only four runs all weekend, while the Marlins had to survive a long rain delay and a late comeback to avoid a sweep against the Yankees on Sunday. Miami is 5-1 at home, Cincinnati is 3-0 on the road, and this feels like one of the tighter games on the board. There is also a little more context here than the surface records show. The Reds made the playoffs last season and have started this year by leaning on run
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Boston Red Sox vs Milwaukee Brewers Picks and Predictions April 6th 2026
Milwaukee opens a three-game set at Fenway Park on Monday night, with first pitch scheduled for 6:45 p.m. ET in Boston. The Brewers come in at 7-2, 2-1 on the road, and sitting on top of the NL Central. Boston is 2-7, 1-2 at home, and trying to stop another slide after dropping two straight to San Diego. The game is on NESN and Brewers.TV, and the weather looks chilly even by early-April standards, with game-time temperatures in the mid to upper 40s and a noticeable breeze. This is a pretty clean handicap on paper. Milwaukee has been the better offense, the steadier pitching staff, and the better overall team through the first nine games. The Brewers just took a

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Louisville Cardinals vs. Pittsburgh Panthers Pick & Prediction JANUARY 6th 2024

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The start of Atlantic Coast Conference play hasn’t gone according to plan for Pittsburgh or Louisville. The Panthers (9-5, 0-3 ACC) and … more

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Brigham Young Cougars vs. Cincinnati Bearcats Pick & Prediction JANUARY 6th 2024

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The action heats up for No. 12 BYU and Cincinnati on Saturday when both schools make their Big 12 Conference debuts in … more

A Georgetown Hoyas player drives past a defender.

Georgetown Hoyas vs. DePaul Blue Demons Pick & Prediction JANUARY 6th 2024

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Winless in conference play so far and already falling behind in the Big East standings despite no team playing more than four … more

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Texas Longhorns vs. Texas Tech Red Raiders Pick & Prediction JANUARY 6th 2024

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The road gets much tougher now for No. 20 Texas and surging Texas Tech, who square off on Saturday night in a … more

Iowa Hawkeyes player going up for a contested shot against Rutgers Scarlet Knights defenders during a college basketball game.

Iowa Hawkeyes vs. Rutgers Scarlet Knights Pick & Prediction JANUARY 6th 2024

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Only two teams are still chasing their first Big Ten Conference win, and they intersect Saturday afternoon when Iowa welcomes Rutgers to … more