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Arizona Diamondbacks vs Chicago White Sox Picks and Predictions April 22nd 2026
The White Sox and Diamondbacks meet Wednesday night at Chase Field in Phoenix, with first pitch set for 9:40 p.m. ET on ARID and CHSN. Chicago comes in at 9-14 after blasting Arizona 11-5 on Tuesday, while the Diamondbacks are 13-10 and trying to keep this from turning into a bad home series against a team that came in struggling. Arizona still sits third in the NL West, and Chicago remains fourth in the AL Central, so this is one of those early-season games that matters a little more than it looks at first glance. The opener changed the tone of the matchup. The White Sox have now scored 33 runs over their last four games, and Munetaka Murakami has
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San Francisco Giants vs Los Angeles Dodgers Picks and Predictions April 22nd 2026
The Dodgers and Giants are back at Oracle Park on Wednesday night, with first pitch set for 9:45 p.m. ET in San Francisco. Los Angeles enters this one at 16-7, tied for first in the NL West, while San Francisco is 10-13 and sitting fourth after taking Tuesday’s opener 3-1. The broadcast is set for SportsNet LA and NBC Sports Bay Area. This matchup is still tilted toward Los Angeles because the bigger sample says the Dodgers have been the better club by a wide margin. They are 6-4 over their last 10, they lead the majors in runs among NL West teams shown here with a +55 run differential, and they have been one of the most explosive offenses
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Miami Marlins vs St. Louis Cardinals Picks and Predictions April 22nd 2026
The St. Louis Cardinals, who have won six of their past seven games, may be off to a surprising start to some, but not to manager Oliver Marmol. “It’s exactly what I would’ve anticipated this group to do,” Marmol said on Tuesday prior to a 5-3 Cardinals’ win over the host Miami Marlins. On Wednesday afternoon, both teams will try to take the three-game series. St. Louis has won back-to-back series while Miami hasn’t taken a series since winning two of three against the Chicago White Sox from March 30-April 1. The pitching matchup features a pair of right-handers, Miami’s Janson Junk (0-2, 4.50 ERA) against St. Louis’ Kyle Leahy (2-2, 5.21). Junk has never faced the Cardinals, and the
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San Jose Earthquakes vs Austin Fc Picks and Predictions April 22nd 2026
The San Jose Earthquakes are enjoying the best eight-match start in franchise history and coach Bruce Arena doesn’t want to hear any chatter about a letdown. The destructive Earthquakes (7-1-0, 21 points) have outscored opponents 17-3 and look to inflict more damage when they host Austin FC on Wednesday night. Austin FC (1-3-4, 7 points) is winless in their past six MLS matches (0-3-3). “There are no trap games in this league,” Arena told reporters. “Any team can beat you on a given day in this league. We understand that. It’s going to be a difficult game on Wednesday. We played Austin last year and I think we split with them. … It’s going to be a difficult game.” The
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Real Salt Lake vs Inter Miami Cf Picks and Predictions April 22nd 2026
Inter Miami passed their first test since the surprise departure of coach Javier Mascherano. As interim coach Guillermo Hoyos would attest, having Lionel Messi at his peak helps. The Herons complete a two-game trip through the Rocky Mountains when they play Real Salt Lake on Wednesday in Sandy, Utah. Messi scored on a penalty kick in the 18th minute and set up his own game-winner with a nifty run in the 79th minute of Miami’s 3-2 win over the Colorado Rapids Saturday. The match was played at the Denver Broncos’ stadium before an audience of 75,824 fans. That was the first outing for Miami (4-1-3, 15 points) since Mascherano announced his resignation, citing “personal reasons,” mere months after he guided

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St. Louis Blues vs. Nashville Predators Pick & Prediction FEBRUARY 17th 2024

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Nashville Predators coach Andrew Brunette expressed exasperation after his team absorbed a 9-2 beating from the Dallas Stars Thursday night. “It’s disappointing,” … more

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Dallas Stars vs. Edmonton Oilers Pick & Prediction FEBRUARY 17th 2024

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The Dallas Stars look to keep rolling when they host the Edmonton Oilers on Saturday. The Stars are coming off a 9-2 … more

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Calgary Flames vs. Detroit Red Wings Pick & Prediction FEBRUARY 17th 2024

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After a torrid stretch moved them into playoff position, the Detroit Red Wings likely were due for this step backward. The Red … more

Ottawa Senators hockey player in a black jersey skates during a game, focused on the play.

Chicago Blackhawks vs. Ottawa Senators Pick & Prediction FEBRUARY 17th 2024

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With their season-high, four-game winning streak now in the rearview mirror, the Ottawa Senators will aim to regroup when they visit the … more

A hockey player in a black and gold uniform takes a powerful slap shot on the ice during a game.

Boston Bruins vs. Los Angeles Kings Pick & Prediction FEBRUARY 17th 2024

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The Boston Bruins hope that turning the page to a new game leads to a different result when they host the Los … more