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Seattle Mariners vs Oakland Athletics Picks and Predictions April 22nd 2026
The Athletics need only to look to the top of the third deck in right field at T-Mobile Park to realize the road to the American League West title goes through Seattle. That’s where the Mariners’ 2025 division championship banner hangs. “(The Mariners) were one game away from going to the World Series last year,” the Athletics’ Shea Langeliers said. “Last year, it kind of felt like a dogfight every time we played them. I don’t think it’s going to be any different this year. These early games in the season, you can look back later and realize how much they mean.” Langeliers homered for a second consecutive night Tuesday, leading the A’s to a 5-2 victory as they remained
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Tampa Bay Rays vs Cincinnati Reds Picks and Predictions April 22nd 2026
Cincinnati goes for a sweep Wednesday afternoon at Tropicana Field, with first pitch set for 1:10 p.m. ET on MLB.TV. The Reds come in at 16-8, first in the NL Central, and they have been excellent away from home at 10-2. Tampa Bay is 12-11, second in the AL East, but only 4-4 at home and trying to stop a three-game slide. Even with the Rays still favored, this feels like one of those spots where recent form and price are pulling in opposite directions. The Reds have already taken the first two games of the series, winning 6-1 on Monday and 12-6 on Tuesday. Cincinnati has now won five straight and is chasing a perfect 6-0 road trip, while
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Cleveland Guardians vs Houston Astros Picks and Predictions April 22nd 2026
Houston heads into Progressive Field for Wednesday’s series finale trying to salvage a split after Tuesday’s 8-5 loss. The Astros are 9-16, last in the AL West, and just 2-10 on the road. Cleveland is 14-11, first in the AL Central, and 8-4 at home. First pitch is set for 1:10 p.m. ET, and the conditions look mild for an April afternoon in Cleveland, with temperatures around 60 degrees and only a light breeze. The game state matters here. Cleveland stole Tuesday’s win with a six-run eighth inning after trailing late, while Houston’s bullpen issues showed up again in a series where the Astros have already asked too much from the relief group. Even so, this is not a simple
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Kansas City Royals vs Baltimore Orioles Picks and Predictions April 22nd 2026
The Orioles and Royals wrap up their three-game set Wednesday afternoon at Kauffman Stadium, with first pitch scheduled for 2:10 p.m. ET. Baltimore comes in at 11-13, third in the AL East, while Kansas City is 8-16 and fifth in the AL Central. The series is tied 1-1 after the Royals stole Tuesday’s game 6-5 on a walk-off wild pitch, and that matters because both teams badly need a clean finish to the series after uneven starts. The recent form is not especially flattering for either side. The Orioles have lost six of their last eight and are 4-6 over their last 10, while the Royals just snapped an eight-game skid and are 2-8 over that same stretch. The weather
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Los Angeles Angels vs Toronto Blue Jays Picks and Predictions April 22nd 2026
The Blue Jays and Angels close out their series Wednesday afternoon at Angel Stadium, with first pitch set for 3:07 p.m. ET. Toronto comes in at 10-13, fourth in the AL East, and has a chance to finish a three-game sweep after taking the first two games 5-2 and 4-2. Los Angeles is 11-14, third in the AL West, and trying to stop a four-game slide. The stream is listed on MLB.TV, and the weather setup in Anaheim looks mild, with intervals of clouds and sun and temperatures in the low 70s. This is an interesting market because the Angels are still favored even though Toronto has won three straight overall and already handled this matchup twice in Anaheim. The

Baltimore Orioles vs New York Yankees Picks and Predictions April 29th 2025

Baltimore Orioles vs New York Yankees Picks and Predictions April 29th 2025

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Kyle Gibson Reunites With Orioles for Clash Against Yankees The Baltimore Orioles are calling on a familiar face as they send Kyle … more

A pitcher in a red and white uniform throws a baseball, while a batter stands ready to swing in a sunny baseball stadium.

Toronto Blue Jays vs Boston Red Sox Picks and Predictions April 29th 2025

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Red Sox vs Blue Jays Game Preview: AL East Rivals Reignite in Toronto Two American League East clubs searching for rhythm collide … more

Cincinnati Reds vs St. Louis Cardinals Picks and Predictions April 29th 2025

Cincinnati Reds vs St. Louis Cardinals Picks and Predictions April 29th 2025

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Reds Aim to Stay Hot Against Struggling Cardinals The Cincinnati Reds look to extend their winning streak and continue exploiting the St. … more

A baseball player in a light blue jersey swings a bat during a game.

Pittsburgh Pirates vs Chicago Cubs Picks and Predictions April 29th 2025

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Cubs vs Pirates Game Preview: New Series, Same Urgency When the Chicago Cubs and Pittsburgh Pirates open their three-game series Tuesday night … more

New York Mets vs Arizona Diamondbacks Picks and Predictions April 29th 2025

New York Mets vs Arizona Diamondbacks Picks and Predictions April 29th 2025

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Mets Aim to Stay Explosive Against Diamondbacks After a record-setting performance, the New York Mets return home Tuesday night to host the … more