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Tampa Bay Rays vs Chicago Cubs Picks and Predictions April 6th 2026
Chicago heads to St. Petersburg for Monday’s 4:10 p.m. ET first pitch at Tropicana Field, where both clubs enter 4-5 but with very different moods. The Cubs just split a Sunday doubleheader in Cleveland after Saturday’s rainout, while the Rays won two of three in Minnesota and now come home for their first regular-season game back at the Trop since Hurricane Milton damaged the stadium in October 2024. Monday’s opener is sold out, marking Tampa Bay’s 20th straight home opener sellout, and the game will air on Marquee Sports Network, Rays.TV, and WMOR. This matchup also has a little more texture than the records suggest. Jameson Taillon gets the ball for Chicago, Shane McClanahan starts for Tampa Bay, and the
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Cleveland Guardians vs Kansas City Royals Picks and Predictions April 6th 2026
Kansas City opens AL Central play Monday night at Progressive Field, with first pitch set for 6:10 p.m. ET in Cleveland. The Royals come in 4-5 after dropping the series finale to Milwaukee, while the Guardians are 6-4, leading the division after splitting Sunday’s doubleheader with the Cubs. The stream is on MLB.TV, and the market has Cleveland installed as a slight home favorite in a low-total game, which makes sense with Michael Wacha and Tanner Bibee getting the ball. The weather looks cold and a little unsettled, with temperatures in the mid-40s around first pitch and a chance of light showers during the evening. This is a pretty interesting opener because both teams can make a case. Kansas City
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Pittsburgh Pirates vs San Diego Padres Picks and Predictions April 6th 2026
San Diego opens this series at PNC Park on Monday night, with first pitch set for 6:40 p.m. ET in Pittsburgh. The Padres come in 4-5 and third in the NL West after winning back-to-back games in Boston, while the Pirates are 6-3, third in the NL Central, and riding a five-game winning streak after sweeping Baltimore. Regional coverage is on SportsNet PT, with streaming also available via MLB.TV. The weather looks cold for early April, around 42 degrees at game time with a light breeze and little rain risk, which matters in a park that can already play a bit bigger at night. The pitching matchup is German Marquez against Bubba Chandler, and that is really where this handicap
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Miami Marlins vs Cincinnati Reds Picks and Predictions April 6th 2026
Cincinnati opens a four-game set at loanDepot Park on Monday night, with first pitch scheduled for 6:40 p.m. ET in Miami. Both clubs are 6-3, but they got there differently. The Reds just swept Texas on the road and allowed only four runs all weekend, while the Marlins had to survive a long rain delay and a late comeback to avoid a sweep against the Yankees on Sunday. Miami is 5-1 at home, Cincinnati is 3-0 on the road, and this feels like one of the tighter games on the board. There is also a little more context here than the surface records show. The Reds made the playoffs last season and have started this year by leaning on run
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Boston Red Sox vs Milwaukee Brewers Picks and Predictions April 6th 2026
Milwaukee opens a three-game set at Fenway Park on Monday night, with first pitch scheduled for 6:45 p.m. ET in Boston. The Brewers come in at 7-2, 2-1 on the road, and sitting on top of the NL Central. Boston is 2-7, 1-2 at home, and trying to stop another slide after dropping two straight to San Diego. The game is on NESN and Brewers.TV, and the weather looks chilly even by early-April standards, with game-time temperatures in the mid to upper 40s and a noticeable breeze. This is a pretty clean handicap on paper. Milwaukee has been the better offense, the steadier pitching staff, and the better overall team through the first nine games. The Brewers just took a

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Tulane Green Wave vs. Southern Methodist Mustangs Pick & Prediction DECEMBER 2nd 2023

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Tulane has been the best team in the American Athletic Conference for the last two seasons. SMU would like to unseat the … more

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Alabama Crimson Tide vs. Georgia Bulldogs Pick & Prediction DECEMBER 2nd 2023

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Alabama quarterback Jalen Milroe has gone from outcast to indispensable hero in less than three months. Now fresh off executing the ‘Milroe … more

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Texas Longhorns vs. Oklahoma State Cowboys Pick & Prediction DECEMBER 2nd 2023

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Texas doesn’t control its own destiny to qualify for the College Football Playoff. But a win by the No. 7 Longhorns over … more

Liberty Flames vs. New Mexico State Aggies Pick & Prediction DECEMBER 1st 2023

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There should be no shortage of confidence for the Conference USA championship game. New Mexico State visits No. 24 Liberty with the … more

Washington Huskies vs. Oregon Ducks Pick & Prediction DECEMBER 1st 2023

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The final Pac-12 championship game has it all. An undefeated team. Two top Heisman candidates. The nation’s best two passing attacks. A … more