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Houston Astros vs St. Louis Cardinals Picks and Predictions April 17th 2026
St. Louis opens this series at Daikin Park on Friday night with a 10-8 record, fourth place in the NL Central, and a little momentum after taking the final two games of its set against Cleveland. Houston is 8-12 and sitting fifth in the AL West, but the Astros are still 7-3 at home and the market has them as a modest favorite for the 8:10 p.m. ET first pitch. The game is set to air on Space City Home Network and Cardinals.TV. This matchup is interesting because the Cardinals arrive with the cleaner recent results, while Houston still owns the better overall offensive profile. St. Louis has won two straight and has Jordan Walker carrying the middle of the
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Boston Red Sox vs Detroit Tigers Picks and Predictions April 17th 2026
It is not about how you start, right? The Boston Red Sox are hoping that is the case for the first month of the long and winding Major League Baseball season. Following Wednesday’s series-closing win at the Minnesota Twins, Boston kicks off a challenging seven-game homestand against the surging Detroit Tigers on Friday night. The four-game set extends through Monday’s traditional 11:05 a.m. start on the Patriots’ Day holiday in Massachusetts. “We’re (three) weeks into the season, and we feel like we haven’t played anywhere close to our best baseball. And it could be way worse,” shortstop Trevor Story said. “Once we get rolling and once we get to doing the things that we know we can do on a
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Cleveland Guardians vs Baltimore Orioles Picks and Predictions April 17th 2026
Craig Albernaz spent plenty of time in the home manager’s office during the last two seasons as a coach with the Cleveland Guardians. Now managing the Baltimore Orioles, he is spending this weekend in the other clubhouse while going against his longtime friend, Cleveland skipper Stephen Vogt. Orioles right-hander Chris Bassitt (0-2, 9.00 ERA) takes on Guardians right-hander Tanner Bibee (0-2, 6.38) in the second game of the four-game series on Friday. “We used to say it to each other all the time in the past two years: Can you believe they let us do this?” Albernaz said. “And if you had told me Vogty and I would be managing together, I would say you were out of your mind.
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New York Yankees vs Kansas City Royals Picks and Predictions April 17th 2026
The New York Yankees encountered warmer weather and trouble preventing pitches from leaving their home ballpark during their last series. After allowing 13 homers in their previous four games, the Yankees hope to make better pitches Friday night when they host the Kansas City Royals in the opener of a three-game series. The Yankees allowed three homers through their first 15 games, including their first homestand, which was played in temperatures under 60 degrees. Against the Angels, the average game-time temperature was 82 degrees and the Yankees settled for a four-game split. New York earned a pair of wins in the ninth inning and hit nine homers. Aaron Judge hit four homers in the series but those were not enough
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Pittsburgh Pirates vs Tampa Bay Rays Picks and Predictions April 17th 2026
In a battle of teams off to strong starts, the Tampa Bay Rays will carry a six-game winning streak into the opener of an interleague three-game set against the host Pittsburgh Pirates on Friday. Veteran right-hander Nick Martinez (0-0, 2.16 ERA) will try to extend the Rays’ winning surge to seven in a row when they face the improved Pirates and rookie right-hander Bubba Chandler (0-1, 3.86). The Rays rallied with three runs in the ninth inning on Thursday to complete their first three-game road sweep of the Chicago White Sox since 2019. This feat came on the heels of Tampa Bay’s first home sweep of the New York Yankees since 2018. The Rays have been finding different ways to

New York Mets players celebrate while a San Diego Padres pitcher looks on during their September 18, 2025 MLB matchup.

New York Mets vs San Diego Padres Picks and Predictions September 18th 2025

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Padres vs Mets Picks and Predictions — September 18, 2025 The San Diego Padres and New York Mets meet Thursday afternoon at … more

Boston Red Sox pitcher throws against an Oakland Athletics player running the bases during their September 18, 2025 MLB matchup.

Boston Red Sox vs Oakland Athletics Picks and Predictions September 18th 2025

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Athletics vs Red Sox Picks and Predictions — September 18, 2025 The Oakland Athletics visit Fenway Park to take on the Boston … more

Cincinnati Reds player in red uniform faces off against a Chicago Cubs pitcher in gray during their September 18, 2025 MLB game.

Cincinnati Reds vs Chicago Cubs Picks and Predictions September 18th 2025

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Cubs vs Reds Picks and Predictions — September 18, 2025 The Chicago Cubs head to Great American Ball Park to take on … more

Tampa Bay Rays pitcher prepares to throw while a Toronto Blue Jays player gets ready during their September 18, 2025 matchup.

Tampa Bay Rays vs Toronto Blue Jays Picks and Predictions September 18th 2025

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Blue Jays vs Rays Picks and Predictions — September 18, 2025 The Toronto Blue Jays face off against the Tampa Bay Rays … more

Baltimore Orioles players celebrating as a New York Yankees pitcher throws during their matchup on September 18, 2025.

Baltimore Orioles vs New York Yankees Picks and Predictions September 18th 2025

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Yankees vs Orioles Picks and Predictions — September 18, 2025 The New York Yankees travel to Camden Yards to take on the … more