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Chicago Cubs vs Philadelphia Phillies Picks and Predictions April 21st 2026
The Phillies head back into Wrigley Field on Tuesday night at 8-14, and the skid is getting hard to ignore now. Philadelphia has dropped six straight, while Chicago is moving the other way at 13-9 with six consecutive wins. First pitch is set for 7:40 p.m. ET, with Jesús Luzardo facing Shota Imanaga, and the current market has the Cubs as a short home favorite. The game is listed on NBC Sports Philadelphia and Marquee Sports Network. The weather looks a little cleaner than the early-day forecast suggested. Chicago has a thunderstorm risk around early evening, but conditions trend cloudier and then partly cloudy by game time, with temperatures settling in the upper 60s. At Wrigley, that always matters, but
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Kansas City Royals vs Baltimore Orioles Picks and Predictions April 21st 2026
The Orioles go back to work at Kauffman Stadium on Tuesday night after taking Monday’s opener 7-5 in 12 innings. That win moved Baltimore to 11-12 and kept the club in third place in the AL East, while Kansas City dropped to 7-16 and stretched its losing streak to eight games, still stuck in fifth in the AL Central. First pitch is set for 7:40 p.m. ET, and the listed starters are Shane Baz for Baltimore and Kris Bubic for Kansas City. The market has the Royals as a modest home favorite with a total of 9. The weather should stay in the background. Kansas City is expected to be warm and mostly clear around first pitch, with temperatures in
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Texas Rangers vs Pittsburgh Pirates Picks and Predictions April 21st 2026
The Pirates open this interleague series at Globe Life Field on Tuesday night sitting at 13-9, third in the NL Central, and they come in off a 6-3 win over Tampa Bay. Texas is 11-11, second in the AL West, and trying to stop a two-game slide after back-to-back losses in Seattle. First pitch is set for 8:05 p.m. ET, with Carmen Mlodzinski getting the ball for Pittsburgh and Kumar Rocker starting for the Rangers. Coverage is listed on MLB.TV, and the current market has Texas installed as a modest home favorite with the total at 8.5. The weather should not be the main handicap here even with light rain in the Arlington forecast. Globe Life Field’s retractable roof can
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Colorado Rockies vs San Diego Padres Picks and Predictions April 21st 2026
San Diego opens a three-game set at Coors Field on Tuesday night with a 15-7 record, second place in the NL West, and a 4-0 lead in the season series over Colorado. The Rockies are 9-14, fifth in the division, but they have been better at home than on the road with a 6-4 mark at Coors. First pitch is set for 8:40 p.m. ET, and the game is listed on Padres.TV and Rockies.TV. This is a game where the setting matters. Denver is expected to be warm and dry around first pitch, with temperatures still in the 70s during the evening, which is about as friendly a hitting environment as you can ask for at Coors. The market reflects
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Los Angeles Angels vs Toronto Blue Jays Picks and Predictions April 21st 2026
Toronto goes back to work at Angel Stadium on Tuesday night after taking Monday’s opener 5-2, so this is not quite the spot your original setup described. The Blue Jays are now 9-13 and still fifth in the AL East, while the Angels are 11-13, third in the AL West, and trying to stop a three-game skid. First pitch is set for 9:38 p.m. ET, with Patrick Corbin starting for Toronto and Jack Kochanowicz getting the ball for Los Angeles. The market has this one close to a coin flip, with the Angels holding a slight edge at home. Coverage is listed on SN1 and FanDuel Sports Network West. The weather should stay in the background. Anaheim is expected to

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Illinois Fighting Illini vs. Minnesota Golden Gophers Pick & Prediction FEBRUARY 28th 2024

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Minnesota has not posted a .500 or better record in Big Ten play since 2016-17 — the league’s longest dry spell. Not … more

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Texas A&M Aggies vs. South Carolina Gamecocks Pick & Prediction FEBRUARY 28th 2024

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No. 18 South Carolina’s place in the NCAA Tournament has seemed like a sure thing since the Gamecocks grabbed first place in … more

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Arizona State Sun Devils vs. Arizona Wildcats Pick & Prediction FEBRUARY 28th 2024

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After a historic loss in the first meeting this season against its in-state rival, Arizona State will get a second chance at … more

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Iowa State Cyclones vs. Oklahoma Sooners Pick & Prediction FEBRUARY 28th 2024

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Iowa State’s start to the Big 12 schedule was shaky. The Cyclones began with a loss at Oklahoma, falling 71-63 on Jan. … more

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Mississippi Rebels vs. Alabama Crimson Tide Pick & Prediction FEBRUARY 28th 2024

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Alabama is tied with Tennessee for first place in the Southeastern Conference. And the Crimson Tide reside toward the middle of the … more