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Los Angeles Angels vs Toronto Blue Jays Picks and Predictions April 21st 2026
Toronto goes back to work at Angel Stadium on Tuesday night after taking Monday’s opener 5-2, so this is not quite the spot your original setup described. The Blue Jays are now 9-13 and still fifth in the AL East, while the Angels are 11-13, third in the AL West, and trying to stop a three-game skid. First pitch is set for 9:38 p.m. ET, with Patrick Corbin starting for Toronto and Jack Kochanowicz getting the ball for Los Angeles. The market has this one close to a coin flip, with the Angels holding a slight edge at home. Coverage is listed on SN1 and FanDuel Sports Network West. The weather should stay in the background. Anaheim is expected to
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Arizona Diamondbacks vs Chicago White Sox Picks and Predictions April 21st 2026
The White Sox open a three-game set at Chase Field on Tuesday night with first pitch scheduled for 9:40 p.m. ET. Chicago comes in at 8-14 and fourth in the AL Central, while Arizona is 13-9, third in the NL West, and 7-3 at home. Sean Burke gets the ball for the White Sox against Merrill Kelly for Arizona, and the market has the Diamondbacks sitting as a moderate home favorite. TV coverage is listed on Dbacks.TV and Chicago Sports Network. This is not really a weather game in the usual sense, but it is worth noting that Chase Field’s roof status for Tuesday is listed as open. Phoenix is expected to be hot and dry during the day, so
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Seattle Mariners vs Athletics Picks and Predictions April 21st 2026
The Athletics head into T-Mobile Park on Tuesday night at 12-11, and after Monday’s 6-4 win in Seattle they sit alone atop the AL West for the moment. The Mariners are 10-14 and fourth in the division, though their 9-6 home record tells a slightly different story than the overall mark. First pitch is set for 9:40 p.m. ET, with Jacob Lopez lined up for the A’s and Luis Castillo getting the ball for Seattle. The market has Seattle favored in the mid -170 range with a total of 7.5, and the game will be carried locally on NBC Sports California and Mariners.TV. The weather angle is softer than it would be in most parks. Seattle is dealing with a
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San Francisco Giants vs Los Angeles Dodgers Picks and Predictions April 21st 2026
The Dodgers open this NL West set at Oracle Park on Tuesday night with first pitch set for 9:45 p.m. ET, 6:45 p.m. local time. Los Angeles comes in at 16-6 and sitting on top of the division, while San Francisco is 9-13 and trying to stabilize after a slow first three weeks. This is the first regular-season meeting between the clubs in 2026, and the market still has the Dodgers installed as the road favorite behind Yoshinobu Yamamoto against Landen Roupp. The game will air on SportsNet LA and NBC Sports Bay Area. There is some weather noise here, too, and that matters more than usual at Oracle. Forecasts call for rain chances tapering into the evening, with temperatures
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Miami Marlins vs St. Louis Cardinals Picks and Predictions April 21st 2026
JJ Wetherholt, off to a solid start to his rookie season, and the St. Louis Cardinals will look to bounce back on Tuesday after dropping the opener of a three-game series against the host Miami Marlins. The 23-year-old second baseman, who went 0-for-3 in a 5-3 loss on Monday, is hitting .228 with three homers, 11 RBIs, four steals and a .730 OPS in 22 games. The Cardinals’ first-round pick, seventh overall, in 2024, Wetherholt mostly played shortstop in the minor leagues but moved to second base because the Cardinals have a Gold Glove winner at his position, Masyn Winn. Still, Wetherholt has above-average tools in terms of his speed, arm, power and hitting, and he has earned the trust

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Oakland Athletics vs. Boston Red Sox Pick & Prediction APRIL 1st 2024

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Two teams that used strong starting pitching as the foundation for series-ending wins in their most recent outings will look for more … more

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San Diego Padres vs. St. Louis Cardinals Pick & Prediction APRIL 1st 2024

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Six games into a 162-game season, the San Diego Padres are showing the type of offensive punch they so often lacked last … more

New York Yankees player celebrates after scoring a run during game against Arizona Diamondbacks

Arizona Diamondbacks vs. New York Yankees Pick & Prediction APRIL 1st 2024

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The Arizona Diamondbacks will host the New York Yankees on Monday night in an early season interleague matchup, a meeting between two … more

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Seattle Mariners vs. Cleveland Guardians Pick & Prediction APRIL 1st 2024

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The Cleveland Guardians expected a lot out of Triston McKenzie last season. Instead, they got just four starts between a pair of … more

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Houston Astros vs. Toronto Blue Jays Pick & Prediction APRIL 1st 2024

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Houston Astros manager Joe Espada had no intention of completing the first series of this season with any fresh players, not after … more