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Seattle Mariners vs Athletics Picks and Predictions April 21st 2026
The Athletics head into T-Mobile Park on Tuesday night at 12-11, and after Monday’s 6-4 win in Seattle they sit alone atop the AL West for the moment. The Mariners are 10-14 and fourth in the division, though their 9-6 home record tells a slightly different story than the overall mark. First pitch is set for 9:40 p.m. ET, with Jacob Lopez lined up for the A’s and Luis Castillo getting the ball for Seattle. The market has Seattle favored in the mid -170 range with a total of 7.5, and the game will be carried locally on NBC Sports California and Mariners.TV. The weather angle is softer than it would be in most parks. Seattle is dealing with a
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San Francisco Giants vs Los Angeles Dodgers Picks and Predictions April 21st 2026
The Dodgers open this NL West set at Oracle Park on Tuesday night with first pitch set for 9:45 p.m. ET, 6:45 p.m. local time. Los Angeles comes in at 16-6 and sitting on top of the division, while San Francisco is 9-13 and trying to stabilize after a slow first three weeks. This is the first regular-season meeting between the clubs in 2026, and the market still has the Dodgers installed as the road favorite behind Yoshinobu Yamamoto against Landen Roupp. The game will air on SportsNet LA and NBC Sports Bay Area. There is some weather noise here, too, and that matters more than usual at Oracle. Forecasts call for rain chances tapering into the evening, with temperatures
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Miami Marlins vs St. Louis Cardinals Picks and Predictions April 21st 2026
JJ Wetherholt, off to a solid start to his rookie season, and the St. Louis Cardinals will look to bounce back on Tuesday after dropping the opener of a three-game series against the host Miami Marlins. The 23-year-old second baseman, who went 0-for-3 in a 5-3 loss on Monday, is hitting .228 with three homers, 11 RBIs, four steals and a .730 OPS in 22 games. The Cardinals’ first-round pick, seventh overall, in 2024, Wetherholt mostly played shortstop in the minor leagues but moved to second base because the Cardinals have a Gold Glove winner at his position, Masyn Winn. Still, Wetherholt has above-average tools in terms of his speed, arm, power and hitting, and he has earned the trust
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Cleveland Guardians vs Houston Astros Picks and Predictions April 21st 2026
The start of Isaac Paredes’ second season with the Houston Astros has not gone according to plan. After he was an All-Star last season, Paredes entered play Monday hitting .190, slugging .254 and homerless after he had 20 long balls last season. He believes things are starting to trend back in the right direction after hitting his first two homers of the season on Monday in the Astros’ 9-2 win over the host Cleveland Guardians in the series opener. Paredes will pursue an encore when the teams meet again in the middle contest of a three-game set on Tuesday. “A lot of happiness because of what I’ve been going through,” Paredes said on the postgame broadcast when asked about his
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Tampa Bay Rays vs Cincinnati Reds Picks and Predictions April 21st 2026
The National League Central-leading Cincinnati Reds have found ways to win despite some dreadful offensive numbers, but their hitters might be finding some form on the current road trip. Winners of four straight to start a six-game trek, the Reds will look for a second consecutive victory over the Tampa Bay Rays on Tuesday in St. Petersburg, Fla. Cincinnati led 2-1 after one inning on Monday and never looked back, cruising to a 6-1 victory. Entering the matchup batting a paltry .178 average with runners in scoring position, the Reds went 4-for-13 on Monday while the Rays finished 0-for-7 in those situations. As a result, Cincinnati logged a ninth win in 11 road outings. While the series opener ended up

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Denver vs. Portland Pick & Prediction FEBRUARY 2nd 2024

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Five years ago, Portland and Denver played an epic seven-game series in the Western Conference semifinals. Since then, the teams have gone … more

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Houston Rockets vs. Toronto Raptors Pick & Prediction FEBRUARY 2nd 2024

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After scoring 130-plus points in three of the previous four games, the Houston Rockets appeared to have resolved at least one of … more

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San Antonio Spurs vs. New Orleans Pelicans Pick & Prediction FEBRUARY 2nd 2024

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The New Orleans Pelicans look to build momentum off a key win when they travel to San Antonio to battle the slumping … more

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Washington Wizards vs. Miami Heat Pick & Prediction FEBRUARY 2nd 2024

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The Miami Heat aim to take another step forward after snapping their longest losing skid in nearly 16 years when they visit … more

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Atlanta Hawks vs. Phoenix Suns Pick & Prediction FEBRUARY 2nd 2024

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The Atlanta Hawks find themselves as healthy as they’ve been all season heading into Friday’s game against the visiting Phoenix Suns. It … more