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Philadelphia Flyers vs Pittsburgh Penguins Picks and Predictions April 22nd 2026
This is Game 3, not some clean slate opener, and that changes the handicap quite a bit. The Pittsburgh Penguins head to Xfinity Mobile Arena on Wednesday night trailing 2-0 in the series after dropping both home games, so the pressure is obvious now. Puck drop is set for 7:00 PM ET on TNT, and Philadelphia has already shown it is comfortable dragging this matchup into the kind of low-event, tight-checking game that frustrates Pittsburgh. That is really the story so far. The Penguins finished the regular season 41-25-16 and were good enough on the road to stay dangerous in this spot, but the Flyers went 43-27-12, earned home ice, and have controlled the tone through two games. Philadelphia has
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Seattle Mariners vs Oakland Athletics Picks and Predictions April 22nd 2026
The Athletics need only to look to the top of the third deck in right field at T-Mobile Park to realize the road to the American League West title goes through Seattle. That’s where the Mariners’ 2025 division championship banner hangs. “(The Mariners) were one game away from going to the World Series last year,” the Athletics’ Shea Langeliers said. “Last year, it kind of felt like a dogfight every time we played them. I don’t think it’s going to be any different this year. These early games in the season, you can look back later and realize how much they mean.” Langeliers homered for a second consecutive night Tuesday, leading the A’s to a 5-2 victory as they remained
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Tampa Bay Rays vs Cincinnati Reds Picks and Predictions April 22nd 2026
Cincinnati goes for a sweep Wednesday afternoon at Tropicana Field, with first pitch set for 1:10 p.m. ET on MLB.TV. The Reds come in at 16-8, first in the NL Central, and they have been excellent away from home at 10-2. Tampa Bay is 12-11, second in the AL East, but only 4-4 at home and trying to stop a three-game slide. Even with the Rays still favored, this feels like one of those spots where recent form and price are pulling in opposite directions. The Reds have already taken the first two games of the series, winning 6-1 on Monday and 12-6 on Tuesday. Cincinnati has now won five straight and is chasing a perfect 6-0 road trip, while
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Cleveland Guardians vs Houston Astros Picks and Predictions April 22nd 2026
Houston heads into Progressive Field for Wednesday’s series finale trying to salvage a split after Tuesday’s 8-5 loss. The Astros are 9-16, last in the AL West, and just 2-10 on the road. Cleveland is 14-11, first in the AL Central, and 8-4 at home. First pitch is set for 1:10 p.m. ET, and the conditions look mild for an April afternoon in Cleveland, with temperatures around 60 degrees and only a light breeze. The game state matters here. Cleveland stole Tuesday’s win with a six-run eighth inning after trailing late, while Houston’s bullpen issues showed up again in a series where the Astros have already asked too much from the relief group. Even so, this is not a simple
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Kansas City Royals vs Baltimore Orioles Picks and Predictions April 22nd 2026
The Orioles and Royals wrap up their three-game set Wednesday afternoon at Kauffman Stadium, with first pitch scheduled for 2:10 p.m. ET. Baltimore comes in at 11-13, third in the AL East, while Kansas City is 8-16 and fifth in the AL Central. The series is tied 1-1 after the Royals stole Tuesday’s game 6-5 on a walk-off wild pitch, and that matters because both teams badly need a clean finish to the series after uneven starts. The recent form is not especially flattering for either side. The Orioles have lost six of their last eight and are 4-6 over their last 10, while the Royals just snapped an eight-game skid and are 2-8 over that same stretch. The weather

San Diego Padres vs Ny Yankees Yankees Picks and Predictions May 25th 2024

San Diego Padres vs Ny Yankees Yankees Picks and Predictions May 25th 2024

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Dylan Cease, Padres Aim to Halt Yankees’ Power Surge Match Preview: Yankees vs. Padres The New York Yankees’ most memorable street game … more

St. Louis Cardinals vs Chi. Cubs Cubs Picks and Predictions May 25th 2024

St. Louis Cardinals vs Chi. Cubs Cubs Picks and Predictions May 25th 2024

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After Rainout, Cardinals Seek to Stay Hot in Clash vs. Cubs The much-anticipated showdown between the Chicago Cubs and St. Louis Cardinals … more

Detroit Tigers vs Toronto Blue Jays Picks and Predictions May 25th 2024

Detroit Tigers vs Toronto Blue Jays Picks and Predictions May 25th 2024

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Tigers Hope Luck is on Reese Olson’s Side vs. Jays Reese Olson’s Tough Luck Reese Olson, despite being one of the most … more

Washington Nationals vs Seattle Mariners Picks and Predictions May 25th 2024

Washington Nationals vs Seattle Mariners Picks and Predictions May 25th 2024

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Nationals Look for Strong Pitching Again in Rematch vs. Mariners Strong Start to a Demanding Stretch The Washington Nationals started off an … more

Chi. White Sox White Sox vs Baltimore Orioles Picks and Predictions May 25th 2024

Chi. White Sox White Sox vs Baltimore Orioles Picks and Predictions May 25th 2024

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Orioles Seek Third Straight Win Over Slumping White Sox Adapting to Challenges The Baltimore Orioles are displaying their versatility this season, showing … more