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Pittsburgh Pirates vs San Diego Padres Picks and Predictions April 6th 2026
San Diego opens this series at PNC Park on Monday night, with first pitch set for 6:40 p.m. ET in Pittsburgh. The Padres come in 4-5 and third in the NL West after winning back-to-back games in Boston, while the Pirates are 6-3, third in the NL Central, and riding a five-game winning streak after sweeping Baltimore. Regional coverage is on SportsNet PT, with streaming also available via MLB.TV. The weather looks cold for early April, around 42 degrees at game time with a light breeze and little rain risk, which matters in a park that can already play a bit bigger at night. The pitching matchup is German Marquez against Bubba Chandler, and that is really where this handicap
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Miami Marlins vs Cincinnati Reds Picks and Predictions April 6th 2026
Cincinnati opens a four-game set at loanDepot Park on Monday night, with first pitch scheduled for 6:40 p.m. ET in Miami. Both clubs are 6-3, but they got there differently. The Reds just swept Texas on the road and allowed only four runs all weekend, while the Marlins had to survive a long rain delay and a late comeback to avoid a sweep against the Yankees on Sunday. Miami is 5-1 at home, Cincinnati is 3-0 on the road, and this feels like one of the tighter games on the board. There is also a little more context here than the surface records show. The Reds made the playoffs last season and have started this year by leaning on run
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Boston Red Sox vs Milwaukee Brewers Picks and Predictions April 6th 2026
Milwaukee opens a three-game set at Fenway Park on Monday night, with first pitch scheduled for 6:45 p.m. ET in Boston. The Brewers come in at 7-2, 2-1 on the road, and sitting on top of the NL Central. Boston is 2-7, 1-2 at home, and trying to stop another slide after dropping two straight to San Diego. The game is on NESN and Brewers.TV, and the weather looks chilly even by early-April standards, with game-time temperatures in the mid to upper 40s and a noticeable breeze. This is a pretty clean handicap on paper. Milwaukee has been the better offense, the steadier pitching staff, and the better overall team through the first nine games. The Brewers just took a
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Washington Nationals vs St. Louis Cardinals Picks and Predictions April 6th 2026
St. Louis opens a three-game set at Nationals Park on Monday night, with first pitch scheduled for 6:45 p.m. ET in Washington. The Cardinals come in 5-4 and fourth in the NL Central after salvaging the finale in Detroit, while the Nationals are 3-6, fifth in the NL East, and trying to stop a five-game slide after getting swept by the Dodgers. MLB.TV has the stream, and the weather looks playable with temperatures around the low 60s at first pitch, very little rain risk, and a light breeze around 10 mph. Andre Pallante gets the ball for St. Louis against Zack Littell for Washington. Pallante’s line is clean after his first outing, 1-0 with a 0.00 ERA, while Littell enters
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Toronto Blue Jays vs Los Angeles Dodgers Picks and Predictions April 6th 2026
Los Angeles opens a three-game set at Rogers Centre on Monday night, with first pitch scheduled for 7:07 p.m. ET in Toronto. The Dodgers come in 7-2, undefeated on the road at 3-0, and sitting atop the NL West after a weekend sweep in Washington. The Blue Jays are 4-5, second in the AL East, and trying to stop a four-game losing streak after getting swept at home by the White Sox. FS1 and MLB.TV have the broadcast for this one, and yes, it is the first meeting between these clubs since the Dodgers finished off last year’s World Series in Toronto. This matchup is interesting because the market is asking you to weigh the Dodgers’ obvious lineup edge against

Indiana Pacers player in a navy jersey with number 33 rises to take a jump shot over a defender.

Indiana Pacers vs. Milwaukee Bucks Pick & Prediction NOVEMBER 9th 2023

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Two Eastern Conference foes playing the second night of back-to-backs face off as the Indiana Pacers oppose the Milwaukee Bucks on Thursday … more

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Arizona Cardinals vs. Atlanta Falcons Pick & Prediction NOVEMBER 12th 2023

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Following a heartbreaking loss to the Minnesota Vikings, the Atlanta Falcons hit the road looking to snap a two-game losing streak against … more

cj Stroud Making a pass

Cincinnati Bengals vs. Houston Texans Pick & Prediction NOVEMBER 12th 2023

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The football world will be watching this week to see what rookie quarterback C.J. Stroud can do for an encore as his … more

San Francisco 49ers player wearing jersey number 23 runs with the football during a game, with the crowd blurred in the background.

Jacksonville Jaguars vs. San Francisco 49ers Pick & Prediction NOVEMBER 12th 2023

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The powerful San Francisco 49ers have gone a month without a victory. Meanwhile, the ever-improving Jacksonville Jaguars haven’t lost since Sept. 24. … more

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Tampa Bay Buccaneers vs. Tennessee Titans Pick & Prediction NOVEMBER 12th 2023

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To paraphrase the late George Allen, the future is now for the Tennessee Titans. By moving on from Ryan Tannehill and naming … more