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Texas Rangers vs Pittsburgh Pirates Picks and Predictions April 22nd 2026
The Pirates and Rangers meet Wednesday night at Globe Life Field in Arlington, with first pitch set for 8:05 p.m. ET. Pittsburgh comes in at 13-10, fifth in the NL Central, while Texas is 12-11 and second in the AL West after opening the series with a 5-1 win on Tuesday. This is a pretty interesting early-season matchup because the records are close, the market is basically flat, and both teams have leaned on pitching more than explosive offense so far. Tuesday’s opener also gave this game a different feel. Texas held Pittsburgh to one run, got six solid innings from Kumar Rocker, and extended its home winning streak to four games, while the Pirates dropped to 5-5 on the
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Colorado Rockies vs San Diego Padres Picks and Predictions April 22nd 2026
The Padres and Rockies are back at Coors Field on Wednesday night, with first pitch set for 8:40 p.m. ET in Denver. San Diego comes in at 16-7 and second in the NL West, while Colorado is 9-15 and fifth after dropping Tuesday’s opener 1-0. The Padres have won three straight, and this is starting to feel like another spot where the better roster is trying to squeeze a divisional opponent before the market fully catches up. San Diego has been much steadier than Colorado in the early season sample, especially away from home. The Padres are 7-3 on the road, and even with an offense that has not fully clicked yet, they keep winning because the run prevention has
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Arizona Diamondbacks vs Chicago White Sox Picks and Predictions April 22nd 2026
The White Sox and Diamondbacks meet Wednesday night at Chase Field in Phoenix, with first pitch set for 9:40 p.m. ET on ARID and CHSN. Chicago comes in at 9-14 after blasting Arizona 11-5 on Tuesday, while the Diamondbacks are 13-10 and trying to keep this from turning into a bad home series against a team that came in struggling. Arizona still sits third in the NL West, and Chicago remains fourth in the AL Central, so this is one of those early-season games that matters a little more than it looks at first glance. The opener changed the tone of the matchup. The White Sox have now scored 33 runs over their last four games, and Munetaka Murakami has
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San Francisco Giants vs Los Angeles Dodgers Picks and Predictions April 22nd 2026
The Dodgers and Giants are back at Oracle Park on Wednesday night, with first pitch set for 9:45 p.m. ET in San Francisco. Los Angeles enters this one at 16-7, tied for first in the NL West, while San Francisco is 10-13 and sitting fourth after taking Tuesday’s opener 3-1. The broadcast is set for SportsNet LA and NBC Sports Bay Area. This matchup is still tilted toward Los Angeles because the bigger sample says the Dodgers have been the better club by a wide margin. They are 6-4 over their last 10, they lead the majors in runs among NL West teams shown here with a +55 run differential, and they have been one of the most explosive offenses
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Miami Marlins vs St. Louis Cardinals Picks and Predictions April 22nd 2026
The St. Louis Cardinals, who have won six of their past seven games, may be off to a surprising start to some, but not to manager Oliver Marmol. “It’s exactly what I would’ve anticipated this group to do,” Marmol said on Tuesday prior to a 5-3 Cardinals’ win over the host Miami Marlins. On Wednesday afternoon, both teams will try to take the three-game series. St. Louis has won back-to-back series while Miami hasn’t taken a series since winning two of three against the Chicago White Sox from March 30-April 1. The pitching matchup features a pair of right-handers, Miami’s Janson Junk (0-2, 4.50 ERA) against St. Louis’ Kyle Leahy (2-2, 5.21). Junk has never faced the Cardinals, and the

Memphis Grizzlies vs. Los Angeles Lakers Pick & Prediction MARCH 27th 2024

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An eventful week for the red-hot Los Angeles Lakers continues when they travel to face the Memphis Grizzlies on Wednesday. Two nights … more

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Orlando Magic vs. Golden State Warriors Pick & Prediction MARCH 27th 2024

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One of the league’s hottest road teams pays a visit to one of the winningest home clubs Wednesday night when the Golden … more

Seattle Mariners batter Mitch Haniger swings at a pitch during a game.

Seattle Mariners vs. Boston Red Sox Pick & Prediction MARCH 28th 2024

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For two teams trying to get back to the postseason, the Boston Red Sox and Seattle Mariners didn’t make any earth-shattering moves … more

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Arizona Diamondbacks vs. Colorado Rockies Pick & Prediction MARCH 28th 2024

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Two seasons after losing 110 games, the Arizona Diamondbacks played in the World Series last season. The stunning accomplishment makes the Diamondbacks … more

Miami Marlins pitcher in a blue jersey winds up to throw a pitch during a game.

Miami Marlins vs. Pittsburgh Pirates Pick & Prediction MARCH 28th 2024

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The Miami Marlins’ selection of an Opening Day starter to face the visiting Pittsburgh Pirates on Thursday afternoon was largely a process … more