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Arizona heads to Philadelphia at 7-6 after winning two straight and seven of its last 10, while the Phillies come in at 6-6 after dropping the final two games of their series in San Francisco. First pitch is set for 6:40 p.m. ET at Citizens Bank Park on Friday night. The market has Philadelphia installed as a solid home favorite, but this is not a one-sided spot, especially with Arizona bringing the hotter recent form into the opener. The actual pitching matchup is Michael Soroka for the Diamondbacks against Jesús Luzardo for the Phillies. Soroka has opened 2-0 with a 0.90 ERA through his first 10 innings for Arizona, while Luzardo is 1-1 with a 4.97 ERA but just bounced

Miami heads to Comerica Park on Friday night at 8-5, while Detroit comes in at 4-9 and trying to stop a five-game slide. First pitch is set for 6:40 p.m. ET in Detroit. The Marlins have won two straight and just took a series in Cincinnati, while the Tigers are back home after getting swept by Minnesota. The market still has Detroit favored, but this is one of those spots where recent form and price do not line up especially cleanly. The pitching matchup is Chris Paddack for Miami against Keider Montero for Detroit. Paddack enters 0-1 with an 8.31 ERA, though Reuters noted his last appearance was a 4 2/3-inning relief outing Sunday in which he allowed one unearned

The Angels head to Great American Ball Park on Friday night at 6-7, looking to stop a two-game skid after dropping the final two games in Atlanta. Cincinnati is 8-5 and has been one of the steadier early teams in the NL Central, even with a recent stumble against Miami. First pitch is set for 6:45 p.m. ET, and the opener of this interleague series puts a live underdog lineup against one of the better early pitching stories in the National League. The starting matchup is Jack Kochanowicz for Los Angeles against Chase Burns for Cincinnati. Kochanowicz enters 1-0 with a 4.66 ERA, while Burns has opened 1-0 with a 0.82 ERA and quickly become a big reason the Reds

Minnesota heads to Rogers Centre on Friday night at 7-6 after sweeping Detroit and extending its winning streak to four games. Toronto is 5-7 and finally snapped a six-game skid with a 4-3 win over the Dodgers on Wednesday, so this opener has two teams arriving with very different recent momentum. First pitch is set for 7:07 p.m. ET in Toronto, and the listed pitching matchup is Simeon Woods Richardson for the Twins against Patrick Corbin for the Blue Jays. This one is interesting because the market still leans Toronto at home even though Minnesota has been the hotter team. A big part of that is venue and lineup context, but there is also some uncertainty around how much to