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Philadelphia Flyers vs Pittsburgh Penguins Picks and Predictions April 22nd 2026
This is Game 3, not some clean slate opener, and that changes the handicap quite a bit. The Pittsburgh Penguins head to Xfinity Mobile Arena on Wednesday night trailing 2-0 in the series after dropping both home games, so the pressure is obvious now. Puck drop is set for 7:00 PM ET on TNT, and Philadelphia has already shown it is comfortable dragging this matchup into the kind of low-event, tight-checking game that frustrates Pittsburgh. That is really the story so far. The Penguins finished the regular season 41-25-16 and were good enough on the road to stay dangerous in this spot, but the Flyers went 43-27-12, earned home ice, and have controlled the tone through two games. Philadelphia has
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Seattle Mariners vs Oakland Athletics Picks and Predictions April 22nd 2026
The Athletics need only to look to the top of the third deck in right field at T-Mobile Park to realize the road to the American League West title goes through Seattle. That’s where the Mariners’ 2025 division championship banner hangs. “(The Mariners) were one game away from going to the World Series last year,” the Athletics’ Shea Langeliers said. “Last year, it kind of felt like a dogfight every time we played them. I don’t think it’s going to be any different this year. These early games in the season, you can look back later and realize how much they mean.” Langeliers homered for a second consecutive night Tuesday, leading the A’s to a 5-2 victory as they remained
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Tampa Bay Rays vs Cincinnati Reds Picks and Predictions April 22nd 2026
Cincinnati goes for a sweep Wednesday afternoon at Tropicana Field, with first pitch set for 1:10 p.m. ET on MLB.TV. The Reds come in at 16-8, first in the NL Central, and they have been excellent away from home at 10-2. Tampa Bay is 12-11, second in the AL East, but only 4-4 at home and trying to stop a three-game slide. Even with the Rays still favored, this feels like one of those spots where recent form and price are pulling in opposite directions. The Reds have already taken the first two games of the series, winning 6-1 on Monday and 12-6 on Tuesday. Cincinnati has now won five straight and is chasing a perfect 6-0 road trip, while
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Cleveland Guardians vs Houston Astros Picks and Predictions April 22nd 2026
Houston heads into Progressive Field for Wednesday’s series finale trying to salvage a split after Tuesday’s 8-5 loss. The Astros are 9-16, last in the AL West, and just 2-10 on the road. Cleveland is 14-11, first in the AL Central, and 8-4 at home. First pitch is set for 1:10 p.m. ET, and the conditions look mild for an April afternoon in Cleveland, with temperatures around 60 degrees and only a light breeze. The game state matters here. Cleveland stole Tuesday’s win with a six-run eighth inning after trailing late, while Houston’s bullpen issues showed up again in a series where the Astros have already asked too much from the relief group. Even so, this is not a simple
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Kansas City Royals vs Baltimore Orioles Picks and Predictions April 22nd 2026
The Orioles and Royals wrap up their three-game set Wednesday afternoon at Kauffman Stadium, with first pitch scheduled for 2:10 p.m. ET. Baltimore comes in at 11-13, third in the AL East, while Kansas City is 8-16 and fifth in the AL Central. The series is tied 1-1 after the Royals stole Tuesday’s game 6-5 on a walk-off wild pitch, and that matters because both teams badly need a clean finish to the series after uneven starts. The recent form is not especially flattering for either side. The Orioles have lost six of their last eight and are 4-6 over their last 10, while the Royals just snapped an eight-game skid and are 2-8 over that same stretch. The weather

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Alabama Crimson Tide vs. Arkansas Razorbacks Pick & Prediction OCTOBER 10th 2023

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Jalen Milroe no longer has to look over his shoulder and is firmly entrenched as Alabama’s starting quarterback. Benched earlier this season, … more

Kentucky Wildcats quarterback hands off the football to a teammate.

Kentucky Wildcats vs. Missouri Tigers Pick & Prediction OCTOBER 10th 2023

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No. 24 Kentucky will look for quarterback Devin Leary to get back on target when the Wildcats host Missouri on Saturday in … more

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Houston Cougars vs. West Virginia Mountaineers Pick & Prediction OCTOBER 10th 2023

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Surprising West Virginia will put its four-game winning streak on the line and will look to remain unbeaten in Big 12 play … more

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Purdue Boilermakers vs. Ohio State Buckeyes Pick & Prediction OCTOBER 10th 2023

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Ohio State wants its third trip to the state of Indiana this season to be as successful as the first two when … more

Duke Blue Devils quarterback runs with the football against NC State Wolfpack defense during NCAA game on October 10, 2023.

Duke Blue Devils vs. NC State Wolfpack Pick & Prediction OCTOBER 10th 2023

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The quarterback topic is running hot when it comes to Saturday night’s Atlantic Coast Conference game between visiting North Carolina State and … more