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Seattle Mariners vs Oakland Athletics Picks and Predictions April 22nd 2026
The Athletics need only to look to the top of the third deck in right field at T-Mobile Park to realize the road to the American League West title goes through Seattle. That’s where the Mariners’ 2025 division championship banner hangs. “(The Mariners) were one game away from going to the World Series last year,” the Athletics’ Shea Langeliers said. “Last year, it kind of felt like a dogfight every time we played them. I don’t think it’s going to be any different this year. These early games in the season, you can look back later and realize how much they mean.” Langeliers homered for a second consecutive night Tuesday, leading the A’s to a 5-2 victory as they remained
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Tampa Bay Rays vs Cincinnati Reds Picks and Predictions April 22nd 2026
Cincinnati goes for a sweep Wednesday afternoon at Tropicana Field, with first pitch set for 1:10 p.m. ET on MLB.TV. The Reds come in at 16-8, first in the NL Central, and they have been excellent away from home at 10-2. Tampa Bay is 12-11, second in the AL East, but only 4-4 at home and trying to stop a three-game slide. Even with the Rays still favored, this feels like one of those spots where recent form and price are pulling in opposite directions. The Reds have already taken the first two games of the series, winning 6-1 on Monday and 12-6 on Tuesday. Cincinnati has now won five straight and is chasing a perfect 6-0 road trip, while
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Cleveland Guardians vs Houston Astros Picks and Predictions April 22nd 2026
Houston heads into Progressive Field for Wednesday’s series finale trying to salvage a split after Tuesday’s 8-5 loss. The Astros are 9-16, last in the AL West, and just 2-10 on the road. Cleveland is 14-11, first in the AL Central, and 8-4 at home. First pitch is set for 1:10 p.m. ET, and the conditions look mild for an April afternoon in Cleveland, with temperatures around 60 degrees and only a light breeze. The game state matters here. Cleveland stole Tuesday’s win with a six-run eighth inning after trailing late, while Houston’s bullpen issues showed up again in a series where the Astros have already asked too much from the relief group. Even so, this is not a simple
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Kansas City Royals vs Baltimore Orioles Picks and Predictions April 22nd 2026
The Orioles and Royals wrap up their three-game set Wednesday afternoon at Kauffman Stadium, with first pitch scheduled for 2:10 p.m. ET. Baltimore comes in at 11-13, third in the AL East, while Kansas City is 8-16 and fifth in the AL Central. The series is tied 1-1 after the Royals stole Tuesday’s game 6-5 on a walk-off wild pitch, and that matters because both teams badly need a clean finish to the series after uneven starts. The recent form is not especially flattering for either side. The Orioles have lost six of their last eight and are 4-6 over their last 10, while the Royals just snapped an eight-game skid and are 2-8 over that same stretch. The weather
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Los Angeles Angels vs Toronto Blue Jays Picks and Predictions April 22nd 2026
The Blue Jays and Angels close out their series Wednesday afternoon at Angel Stadium, with first pitch set for 3:07 p.m. ET. Toronto comes in at 10-13, fourth in the AL East, and has a chance to finish a three-game sweep after taking the first two games 5-2 and 4-2. Los Angeles is 11-14, third in the AL West, and trying to stop a four-game slide. The stream is listed on MLB.TV, and the weather setup in Anaheim looks mild, with intervals of clouds and sun and temperatures in the low 70s. This is an interesting market because the Angels are still favored even though Toronto has won three straight overall and already handled this matchup twice in Anaheim. The

Chi. White Sox White Sox vs Baltimore Orioles Picks and Predictions May 24th 2024

Chi. White Sox White Sox vs Baltimore Orioles Picks and Predictions May 24th 2024

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White Sox aim to make up for controversial defeat in upcoming game against Orioles. In search of inspiration through debate. The Chicago … more

Minnesota Twins vs Texas Rangers Picks and Predictions May 24th 2024

Minnesota Twins vs Texas Rangers Picks and Predictions May 24th 2024

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Upbeat Twins Hoping to Stay Hot vs. Reeling Rangers Surfing on the wave of victories The Minnesota Twins are excited as they … more

Oakland Athletics vs Houston Astros Picks and Predictions May 24th 2024

Oakland Athletics vs Houston Astros Picks and Predictions May 24th 2024

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Daz Cameron, A’s Set to Challenge Astros’ Justin Verlander Cameron’s Great Chance Daz Cameron will have a unique opportunity to face the … more

San Diego Padres vs Ny Yankees Yankees Picks and Predictions May 24th 2024

San Diego Padres vs Ny Yankees Yankees Picks and Predictions May 24th 2024

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Yu Darvish of the Padres aims to continue his streak of not allowing any runs against the Yankees. Darvish’s impressive run of … more

La Angels Angels vs Cleveland Guardians Picks and Predictions May 24th 2024

La Angels Angels vs Cleveland Guardians Picks and Predictions May 24th 2024

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Angels Have Faith in Infielder Kyren Paris as Guardians Come to Anaheim Despite a rocky launch in Double- A, Los Angeles Angels … more