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Flamengo travel to face Estudiantes de la Plata in Copa Libertadores Group A on Wednesday, April 29, 2026, at Estadio Jorge Luis Hirschi in La Plata. Kickoff is set for 8:30 PM ET, and this is a direct top-of-the-group matchup with real control of the section at stake. Flamengo enter first in Group A with six points from two matches, six goals scored, and just one allowed. Estudiantes are second with four points after drawing away to Independiente Medellín and beating Cusco FC at home. So, while Flamengo are the sharper team on recent form, Estudiantes are unbeaten in the group and can move top with a home win. The market leans Flamengo, which is fair. They are in excellent

Palmeiras travel to face Cerro Porteño in Copa Libertadores Group F on Wednesday, April 29, 2026, at Estadio General Pablo Rojas in Asunción. Kickoff is set for 8:30 PM ET, and this is a useful pressure spot because Palmeiras are trying to stay in control of the group, while Cerro Porteño need the home result to keep pace. Cerro are not in a bad position after beating Junior 1-0, but the margin for error is thin. They lost their opener to Sporting Cristal, and now they get the toughest opponent in the section. Palmeiras, meanwhile, have already taken points from both group matches and arrive in strong overall form. The market has Palmeiras as the favorite, which makes sense. Still,

Universidad Católica travel to face Barcelona SC in Copa Libertadores Group D on Wednesday, April 29, 2026, at Estadio Monumental Banco Pichincha in Guayaquil. Kickoff is set for 8:00 PM ET, and this is a pressure-heavy group-stage spot for both clubs, just in different ways. Barcelona SC are bottom of the group with zero points through two matches. They lost 1-0 at home to Cruzeiro and then 3-0 away to Boca Juniors, so this is already close to a must-win spot if they want to stay alive in the group. Universidad Católica are in a better position after beating Cruzeiro away, but they also lost to Boca Juniors, so a road point here would still carry real value. The market

Independiente Santa Fe travel to face Platense in Copa Libertadores Group E on Wednesday, April 29, 2026, at Estadio Ciudad de Vicente López in Buenos Aires. Kickoff is set for 6:00 PM ET, and the group table makes this a pretty uncomfortable spot for the visitors. Platense are sitting second in Group E and can strengthen their qualification position with a home win. Santa Fe are fourth, which puts more pressure on them to take something from this trip. A loss would leave them chasing the group, and that changes how aggressive they may need to be as the match moves into the second half. The market has Platense favored, and that makes sense at home. Still, this is not