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Cleveland Guardians vs Houston Astros Picks and Predictions April 22nd 2026
Houston heads into Progressive Field for Wednesday’s series finale trying to salvage a split after Tuesday’s 8-5 loss. The Astros are 9-16, last in the AL West, and just 2-10 on the road. Cleveland is 14-11, first in the AL Central, and 8-4 at home. First pitch is set for 1:10 p.m. ET, and the conditions look mild for an April afternoon in Cleveland, with temperatures around 60 degrees and only a light breeze. The game state matters here. Cleveland stole Tuesday’s win with a six-run eighth inning after trailing late, while Houston’s bullpen issues showed up again in a series where the Astros have already asked too much from the relief group. Even so, this is not a simple
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Kansas City Royals vs Baltimore Orioles Picks and Predictions April 22nd 2026
The Orioles and Royals wrap up their three-game set Wednesday afternoon at Kauffman Stadium, with first pitch scheduled for 2:10 p.m. ET. Baltimore comes in at 11-13, third in the AL East, while Kansas City is 8-16 and fifth in the AL Central. The series is tied 1-1 after the Royals stole Tuesday’s game 6-5 on a walk-off wild pitch, and that matters because both teams badly need a clean finish to the series after uneven starts. The recent form is not especially flattering for either side. The Orioles have lost six of their last eight and are 4-6 over their last 10, while the Royals just snapped an eight-game skid and are 2-8 over that same stretch. The weather
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Los Angeles Angels vs Toronto Blue Jays Picks and Predictions April 22nd 2026
The Blue Jays and Angels close out their series Wednesday afternoon at Angel Stadium, with first pitch set for 3:07 p.m. ET. Toronto comes in at 10-13, fourth in the AL East, and has a chance to finish a three-game sweep after taking the first two games 5-2 and 4-2. Los Angeles is 11-14, third in the AL West, and trying to stop a four-game slide. The stream is listed on MLB.TV, and the weather setup in Anaheim looks mild, with intervals of clouds and sun and temperatures in the low 70s. This is an interesting market because the Angels are still favored even though Toronto has won three straight overall and already handled this matchup twice in Anaheim. The
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Seattle Mariners vs Athletics Picks and Predictions April 22nd 2026
The Athletics head into Wednesday’s series finale at T-Mobile Park with a 13-11 record, first place in the AL West, and wins in the first two games of this set. Seattle is 10-15, fourth in the division, and trying to avoid a home sweep after dropping games by 6-4 and 5-2. First pitch is set for 4:10 p.m. ET, with the game listed on MLB.TV. This is a better spot than it might look at first glance for Oakland. The Athletics are 6-4 in their last 10 and 8-6 on the road, while Seattle is 4-6 in its last 10 even though it has played much better at home than away. The Mariners are 9-7 at T-Mobile Park, but their
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Detroit Tigers vs Milwaukee Brewers Picks and Predictions April 22nd 2026
The Brewers and Tigers meet Wednesday night at Comerica Park, with first pitch set for 6:40 p.m. ET in Detroit. Milwaukee comes in at 13-9, fourth in the NL Central, while Detroit is 12-12 and third in the AL Central. The Brewers snapped back with a 12-4 win in Tuesday’s opener, while the Tigers are trying to stop a two-game skid after what was easily one of their sloppier bullpen games of the young season. TV coverage is listed as Brewers.TV and Detroit SportsNet, and the current market has Detroit as a modest home favorite with a low total of 7.5. This is a pretty interesting spot because the records are close, but the game shape is a little different

NCAAB picks and predictions preview graphic for East Texas A&M Lions vs UT Rio Grande Valley Vaqueros featuring both team logos, a matchup-themed background image, and the ScoresandStats logo.

East Texas A&M Lions vs Texas-Rio Grande Valley Vaqueros Picks and Predictions February 28th 2026

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East Texas A&M Lions vs Texas-Rio Grande Valley Vaqueros Picks and Predictions February 28th 2026 East Texas A&M Lions hit the road … more

Virginia Tech Hokies vs North Carolina Tar Heels Picks and Predictions February 28th 2026

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ACC action takes center stage Saturday night as the Virginia Tech Hokies travel to Chapel Hill to face the North Carolina Tar … more

Tarleton State Texans vs California Baptist Lancers Picks and Predictions February 28th 2026

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Late-night WAC action heads to Riverside as the Tarleton State Texans visit the California Baptist Lancers at the Dale E. and Sarah … more

Yale Bulldogs vs Cornell Big Red Picks and Predictions February 27th 2026

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Yale Bulldogs vs Cornell Big Red Game Preview Yale heads to Ithaca on Friday night for an Ivy League matchup with Cornell … more

NBA game preview image featuring players from the Boston Celtics and Brooklyn Nets, with team logos displayed and text stating "Celtics vs Nets."

Boston Celtics vs Brooklyn Nets Picks and Predictions February 27, 2026

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The Boston Celtics return to the parquet at TD Garden this Friday, February 27, 2026, to host the Brooklyn Nets. Tipoff is … more