NFL Previews 
MLB Previews 
NBA Previews 
NHL Previews 
Soccer Previews 
NFL Week 12 Picks – Holiday Week Heaters and Betting Gold
It’s Thanksgiving week in the NFL, and Week 12 delivers a buffet of football—and betting opportunity. With rivalry games, playoff stakes, and short-week complications, there’s no better time to let the experts at Scores and Stats guide your game plan.
Looking for smart angles during a wild week of travel, distractions, and tight turnarounds? Our latest NFL picks cut through the noise. We focus on trends that matter, matchup edges, and metrics that thrive under holiday pressure.
2025 NFL Week 12 Schedule
Week 12 includes the annual Thanksgiving triple-header, plus key Sunday clashes and a Monday night finale with postseason positioning on the line. It’s one of the most unique slates of the season—filled with emotional swings and sneaky betting value.
It all kicks off Thursday with a nationally televised set of games that always draw heavy action, followed by a full Sunday lineup and a spotlight Monday Night Football game with major playoff implications. The energy’s high. The lines are sharp. Be ready.
| Date | Matchup | Time | Location |
|---|---|---|---|
| Thursday, November 20, 2025 | Buffalo @ Houston | 7:15 PM | NRG Stadium, Houston, TX |
| Sunday, November 23, 2025 | Pittsburgh @ Chicago | 12:00 PM | Soldier Field, Chicago, IL |
| Sunday, November 23, 2025 | New England @ Cincinnati | 12:00 PM | Paycor Stadium, Cincinnati, OH |
| Sunday, November 23, 2025 | New York @ Detroit | 12:00 PM | Ford Field, Detroit, MI |
| Sunday, November 23, 2025 | Minnesota @ Green Bay | 12:00 PM | Lambeau Field, Green Bay, WI |
| Sunday, November 23, 2025 | Seattle @ Tennessee | 12:00 PM | Nissan Stadium, Nashville, TN |
| Sunday, November 23, 2025 | Indianapolis @ Kansas City | 12:00 PM | GEHA Field at Arrowhead Stadium, Kansas City, MO |
| Sunday, November 23, 2025 | New York @ Baltimore | 12:00 PM | M&T Bank Stadium, Baltimore, MD |
| Sunday, November 23, 2025 | Cleveland @ Las Vegas | 3:05 PM | Allegiant Stadium, Las Vegas, NV |
| Sunday, November 23, 2025 | Jacksonville @ Arizona | 3:05 PM | State Farm Stadium, Glendale, AZ |
| Sunday, November 23, 2025 | Philadelphia @ Dallas | 3:25 PM | AT&T Stadium, Arlington, TX |
| Sunday, November 23, 2025 | Atlanta @ New Orleans | 3:25 PM | Caesars Superdome, New Orleans, LA |
| Sunday, November 23, 2025 | Tampa Bay @ Los Angeles | 7:20 PM | SoFi Stadium, Inglewood, CA |
| Monday, November 24, 2025 | Carolina @ San Francisco | 7:15 PM | Levi’s Stadium, Santa Clara, CA |
NFL Handicapping Leaderboard
At this point, bettors need to think like coaches. Our Top Handicappers are factoring in snap counts, coaching tendencies, and in-season fatigue to uncover where the public may be overreacting—and where real value is hiding.
Our Week 12 expert picks span the spread, totals, and moneyline markets, offering analysis built for both seasoned bettors and anyone looking to spice up their holiday weekend with a smart wager or two.
NFL Week 12 Picks
Check out our updated NFL Week 12 odds and predictions for the latest insight on every game. We’ve got the trends, injury news, and betting signals you need to cash in before the turkey hits the table.
Feast on Week 12 Wins with Scores and Stats
This isn’t just another week—it’s a pivotal one. With compressed schedules and emotional swings, Week 12 is made for bettors who stay focused and follow the right intel. Let Scores and Stats give you the winning formula from Thursday to Monday.
Tap into expert picks, strategy breakdowns, and late-breaking news by following us on Instagram @scoresandstats, X @scoresand_stats, and YouTube, where we cover holiday betting angles, value traps, and best bets all weekend long.
From current NFL odds to deep-dive game previews, we’re your trusted source for turning football knowledge into betting wins. Let’s make Week 12 a feast—for your bankroll.
Unlock Access to NFL Winner’s Circle
Join now—it’s free.
