NFL Week 12 Odds and Predictions 2026: Picks for Every Game

Wednesday, November 25 · 8:00 PM ET

Conference

Conference, not division: no rematch to correct it, which makes the single result heavier than it feels. A Wednesday kickoff, which exists once a year and disrupts a week built around Sundays. We would want a reason to be on the favourite here beyond the fact that they are the favourite.

Thursday, November 26 · 1:00 PM ET

Divisional

In the division, where the margin matters as much as the result once the tiebreakers are counted. One of three on Thanksgiving Day, and the holiday games take more casual money than anything else on the card. We would leave this alone until the injury report lands.

Thursday, November 26 · 4:30 PM ET

Divisional

The second division meeting of the year. The first one is on tape and has been watched more than once. Played on Thanksgiving, which changes nothing about the football and everything about who is watching. We think the honest answer is that this one is close, and close games are where prices get lazy.

Thursday, November 26 · 8:20 PM ET

Conference

In the conference. It will be a line on a tiebreaker sheet in January and nobody will remember the afternoon. Thanksgiving football, in front of an audience that does not watch the other fifteen games. Our view: the number will move more than the matchup warrants.

Friday, November 27 · 3:00 PM ET

Conference

Conference game. The winner takes a game the loser cannot get back from anywhere else. Black Friday afternoon, alone on the board, in a window the NFL only started using recently. Our read: the total tells you more about what the books expect than the side does.

Sunday, November 29 · 1:00 PM ET

Interconference

Across the conferences. The result counts once and then stops counting. A one o’clock start, one of a crowded slate, which is where an edge is easiest to find and hardest to notice. Our view: the public will be on one side of this by Friday, and that is worth knowing before Sunday.

Sunday, November 29 · 1:00 PM ET

Conference

Same conference, no tiebreaker, but it moves the conference record that seeds the bracket. A bye behind the Browns, and the healthy version of a team is a genuine variable, and the hardest one of all to price. The obvious side is the popular side, and those are not always the same bet.

Sunday, November 29 · 1:00 PM ET

Interconference

Non-conference, played once every four years by rotation, so neither side has much recent tape on the other. A retractable roof, which takes the weather out of the question if they want it out. We would rather have the points here than the opinion.

Sunday, November 29 · 1:00 PM ET

Divisional

Second time these two have met this season, in the division. Adjustments, not surprises. The early window, where the schedule puts games it does not expect to argue about. Our read: this is a total to look at before it is a side.

Sunday, November 29 · 1:00 PM ET

Conference

A conference game. Nothing head-to-head to win, but conference record separates teams level on wins. One side here, the Falcons, has had a week off. Rested is easy to say and hard to put a number on. We think the market is closer to right here than the talk suggests.

Sunday, November 29 · 1:00 PM ET

Conference

In-conference, which matters in January rather than now: it is the record that breaks ties between strangers. Under a roof that opens when it suits, so the forecast is a choice rather than a condition. Our view: this is the sort of game people are certain about for no good reason.

Sunday, November 29 · 4:05 PM ET

Divisional

Second division game between these two. The margin matters: point differential in the division is a live tiebreaker. In the late window, which means a full afternoon of results before anyone kicks off. Our view: wait for the number rather than the news.

Sunday, November 29 · 4:25 PM ET

Conference

Within the conference. It will not look important until two teams finish level. The visitor crosses 2 time zones going west, which is the cheap direction. It is the flight home that costs teams games nobody attributes to it. We would take the home side’s price more seriously than the home side’s reputation.

Sunday, November 29 · 4:25 PM ET

Divisional

The return division game, and a rematch is where the first result gets tested rather than repeated. The Seahawks have had two weeks to look at this one. That edge is real and it is mostly preparation, not legs. Our read: the line that opens is not the line that settles, and the gap is the whole edge.

Sunday, November 29 · 8:20 PM ET

Conference

Conference game, and those are the quiet ones that decide seeding three months later. The Patriots come off a bye, which buys a fortnight of preparation for one opponent. The rest is worth less than people think; the extra week of film is worth more. We are interested in this one late, not early.

Monday, November 30 · 8:15 PM ET

Divisional

Second division meeting, and the tiebreaker either changes hands here or stops being available. The Monday nightcap: the last line on the board to move, and the only game played knowing what everything else did. We think the market is closer to right here than the talk suggests.