Chicago White Sox vs Minnesota Twins Picks and Predictions September 1st 2025

Chicago White Sox vs Minnesota Twins September 1st 2025

The Chicago White Sox will visit the Minnesota Twins at Target Field on Monday, September 1, 2025. The game will start at 2:10 PM and will be broadcast on MNNT. The weather forecast predicts a mild day with a light breeze and clear skies.

The White Sox hold a record of 49-88, sitting fifth in the AL Central. They recently broke a losing streak with a win. The Twins, with a record of 62-74, are fourth in the division. Both teams have won four of their last ten games. Aaron Civale will start for the White Sox, while Bailey Ober will take the mound for the Twins.

White Sox vs Twins Key Information

• Sport: Baseball
• Teams: Chicago White Sox vs. Minnesota Twins
• Venue: Target Field in Minneapolis, MN
• Date: Monday, September 1, 2025
• Betting Odds: White Sox Moneyline +150, Twins Moneyline -180

The White Sox Can Win If…

The Chicago White Sox come into this game after a close 3-2 win against the New York Yankees. Martín Pérez was solid on the mound, pitching six innings and allowing just two runs. Lenyn Sosa and Colson Montgomery both hit home runs, providing the needed offense to secure the win.

Chicago’s lineup has power potential, with Lenyn Sosa leading the team with 18 home runs. The White Sox rank 20th in the league for home runs, showing they can go deep when needed. Their ability to hit extra-base hits, as seen in recent games, can be a game-changer.

On the mound, Aaron Civale will start for the White Sox. While his season ERA is 5.26, he has shown the ability to strike out batters, which could be key against the Twins. The White Sox bullpen has been reliable, ranking 6th in the league for fewest blown saves, which could help secure a late lead.

The Twins Can Win If…

The Minnesota Twins are coming off a strong 7-2 win against the San Diego Padres. Joe Ryan led the way with a dominant pitching performance, going seven innings and allowing no runs. Byron Buxton also shined, hitting a home run and driving in two runs.

The Twins have shown they can win with power, ranking 12th in home runs this season. Byron Buxton is a key player, with 29 home runs and a .271 batting average. Their ability to hit the long ball gives them a chance to score quickly and put pressure on the opposing team.

Bailey Ober will start for the Twins, looking to improve his record. While his ERA is 5.14, he has the potential to keep the game close. With a lineup that includes Buxton, Trevor Larnach, and Luke Keaschall, the Twins have the offensive tools to support their pitching and win the game.

Want to see how other contenders are performing? Check the latest MLB odds and previews.

The Lean

The Twins are favored on the moneyline at -180, and they have a slight edge in team statistics. The White Sox have a batting average of .233, while the Twins are at .238. My model projects the Twins to win with a score of 5-4. Based on these factors, I recommend taking the Twins on the moneyline.

The total for the game is set at 8.5 runs. The Twins have a team ERA of 4.46, and the White Sox have an ERA of 4.26. My model projects a total score of 9 runs. Given these projections, I recommend betting on the over for this game.

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Byron Buxton Red-Hot as Twins Host White Sox

It’s been a tough 2025 for the Minnesota Twins, but Byron Buxton is ensuring fans still have plenty to cheer about. Fresh off a career milestone, Buxton will look to continue his tear when Minnesota opens a four-game home series against the Chicago White Sox on Monday afternoon.

The Twins enter this matchup after taking two of three from the San Diego Padres, capped by a 7-2 victory Sunday. Buxton sparked the offense with his 29th homer of the year — surpassing his previous single-season high of 28, set in 2022. One more long ball and he’ll reach 30 for the first time in his career.

Buxton’s Career Numbers Against the White Sox

Buxton seems destined to reach that 30-HR mark quickly, given his track record against Chicago. In 96 career games versus the Sox, he’s slashed .281/.345/.584 with 23 home runs — eight more than against any other opponent.

Manager Rocco Baldelli praised his star outfielder:
“Almost every day, you come in and he’s doing something even more impressive, or setting some new mark and doing something great. He had great at-bats all day long.”

White Sox Riding Momentum Into Minneapolis

The White Sox come in with some positive energy of their own, having edged the New York Yankees 3-2 on Sunday to avoid a sweep. Colson Montgomery and Lenyn Sosa each homered, with Sosa continuing his breakout season.

The 25-year-old infielder is hitting .269 with 18 homers and 61 RBIs across 119 games. Manager Will Venable credited Sosa’s improved plate discipline:
“It’s been really cool to see the progression of his year, where it was like on ‘go’ all the time early to where he’s done a really nice job being patient early in the count and being more selective.”

Montgomery also drew confidence from competing against the Yankees:
“You see teams like that, and they have difference-makers. We have guys who can do that, too. In the second half, we’re putting the ball in the seats a lot more. They’re momentum-changers.”

Curious how the White Sox stack up against division rivals? Explore all MLB teams and compare their performance.

Pitching Matchup: Ober vs. TBD

Twins right-hander Bailey Ober (4-7, 5.14 ERA) gets the ball for his 23rd start of the season. It’s been a frustrating run — Ober hasn’t won since May 3 against the Boston Red Sox, going 0-6 with a 5.83 ERA in his last 15 starts.

Still, his career numbers against Chicago are encouraging: 6-2 with a 3.43 ERA across 14 starts, with 78 strikeouts in 76 innings.

The White Sox had planned to start Aaron Civale, but he was claimed off waivers by the Cubs. That leaves journeyman Bryse Wilson as the likely fill-in. Wilson struggled earlier this season (0-2, 6.95 ERA in 19 appearances) before being sent to Triple-A Charlotte.

Key Factors to Watch

1. Buxton’s Power Surge: He’s one homer away from his first 30-HR campaign.
2. Sosa’s Breakout: The White Sox infielder is emerging as a core piece.
3. Pitching Questions: Can Ober finally snap his winless streak? Will Wilson stabilize Chicago’s rotation?
4. Home vs. Road Splits: Minnesota is solid at home (35-32), while Chicago struggles on the road (19-46).

Matchup at a Glance

Looking to wager on this rivalry? Get expert picks at MLB betting guide.

Final Thoughts

This series has plenty of intrigue despite the standings. Buxton’s chase for 30 homers and Ober’s attempt to snap his skid headline Minnesota’s side. For Chicago, Sosa’s steady bat and Wilson’s return to the rotation could swing momentum.

Both teams are out of the playoff picture, but individual performances — and a long-standing divisional rivalry — should make this four-game set worth following.

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