Chicago White Sox vs Seattle Mariners Picks and Predictions May 21st 2025

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The Seattle Mariners are turning heads in the league, not just for their recent performances, but for an emerging pattern of near-flawless pitching. As they prepare for the series finale against the struggling Chicago White Sox this Wednesday, Seattle hopes their pitching excellence will translate into a series win—despite a narrow 1-0 defeat in Game 2.

Seattle’s Pitching: A Wall of Consistency

While their bats fell silent in Tuesday’s shutout, the Mariners’ pitching staff remained sharp. Seattle has now held opponents to just one run in five straight games, drawing comparisons to their legendary 2001 and 2010 squads. With starters and bullpen arms alike delivering clutch innings, it’s clear the strength of this squad lies on the mound.

Logan Evans, Seattle’s rookie right-hander, is set to start in the finale. In just four career starts, Evans has shown remarkable poise. His most recent outing—a six-inning shutout against the Padres—showcased his ability to control the game and minimize damage.

“I don’t know exactly what my role is going to be all year, but for now, it’s to give the team a chance to win,” Evans said. “I feel like I’m doing that.”

Series Snapshot: A Tale of Two Eighth Innings

The opening games of this series hinged on high-pressure, bases-loaded matchups between Mariners slugger Julio Rodriguez and White Sox reliever Cam Booser.

  • Game 1: Rodriguez delivered a thunderous grand slam, sparking a 5-1 Mariners victory.
  • Game 2: Rodriguez struck out, leaving key runs stranded and giving Chicago the edge in a 1-0 win.

This sequence encapsulated the razor-thin margin between victory and defeat for both clubs.

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White Sox: Searching for Spark Amidst Slump

Chicago ended a five-game skid with Tuesday’s win, thanks to another standout performance from Miguel Vargas, who continues to emerge as a central offensive figure.

Vargas, recently named AL Player of the Week, has batted .417 with four home runs and nine RBIs over the last week. He’s also showing confidence at the plate and consistency in approach, a result of what manager Will Venable credits as a key mechanical adjustment.

“He’s obviously impacting the ball and playing good defense. He’s just out there confident and playing baseball,” Venable noted.

Meanwhile, rookie shortstop Chase Meidroth has settled nicely into the leadoff role, extending his hitting streak to eight games and providing a reliable on-base presence for a lineup in need of stability. Check The latest Baseball Picks from MLB Expert Handicappers

Luis Robert Jr. Slumping Hard

While some Sox bats are heating up, center fielder Luis Robert Jr. remains mired in a deep slump. He went 0-for-3 on Tuesday, dropping his season average to .182. Over his last 12 games, Robert has managed just 7 hits in 46 at-bats—a worrisome trend for Chicago.

“I just focus on trying to get better. I can’t think of anything else,” Robert said via an interpreter.

What’s at Stake

For Seattle, a series win would extend their hot pitching streak and solidify their position as AL West contenders. For Chicago, emerging offensive contributors like Vargas and Meidroth offer hope for long-term growth—even if the win column isn’t piling up.

By Taylor Smith | April 8, 2025
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By Taylor Smith | March 29, 2025
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Mike Williams
Mike Williams | Handicapper

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Mike uses his strong sports knowledge to analyze all the angles to find the most profitable wagers. Iron Mike handicaps MLB, college football, NFL, NBA, and NCAA basketball. I'm an actual sports and gambling junkie!

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