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Mariners vs White Sox Prediction: Can Seattle’s New Trio Power Past Chicago?
On Wednesday, August 6, 2025, the Chicago White Sox (42–70) visit the Seattle Mariners (60–53) at T‑Mobile Park. First pitch is at 9:40 PM ET, airing on MLBN. Mariners are big favorites at –259, with the White Sox priced at +214. A breeze and light rain are in the forecast, but the retractable roof should ensure conditions stay comfortable.
Seattle flexed its newly upgraded lineup—led by Eugenio Suárez and Josh Naylor, both acquired at the trade deadline—during an 8–3 win over Chicago. See MLB recaps and scoreboards.
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Chicago White Sox Can Win If…
Chicago showed signs of life despite their loss, as Colson Montgomery launched a homer and drove in four, and Luis Robert Jr. added two hits with an RBI. With 104 team homers and 175 doubles, they can manufacture extra-base damage when the lineup clicks.
They’ll lean on Jonathan Cannon, whose 4.77 ERA has fluctuated—but he still presents a command-based challenge. Chicago’s bullpen ranks 6th in blown saves (only 17), showing enough late-game reliability to hang around.
“Even in losses, you’re going to learn things,” said Sox RHP Davis Martin. “I just don’t think there’s complacency anymore.”
Seattle Mariners Can Win If…
The Mariners continue their momentum by riding the power of recent deadline additions Eugenio Suárez and Josh Naylor, both of whom homered and drove in multiple runs in Tuesday’s win. Their offensive depth now ranks among MLB’s best, with eight players in the top 100 for batting runs above average.
Starter George Kirby brings elite control—he’s notched the lowest walk rate among qualified starters all-time and entered the game with a 2.13 ERA in two career starts vs. Chicago. If he keeps free passes to a minimum and the lineup keeps executing, Seattle should dominate late innings.
Pitching Matchup Comparison
| Pitcher | Team | W‑L (2025) | ERA | WHIP | Career vs Opponent |
|---|---|---|---|---|---|
| George Kirby | Mariners | 6–5 | 4.13 | 1.12 | 1–0, 2.13 ERA in 2 starts vs CWS |
| Jonathan Cannon | White Sox | 4–8 | 4.77 | 1.41 | 0–0, 1.29 ERA in 1 start vs SEA |
Key MLB Betting Trends
- Mariners have won 4 of their last 5 at home; improved to 5–5 in last 10 games
- White Sox are 6–4 since the All-Star break, showing signs of progress
- Seattle now features two high-impact deadline additions in Suárez and Naylor, boosting offensive projection
- Over the last few games, totals have favored the under when Seattle’s rotation and bullpen hold leads
The Lean
Seattle’s trade deadline reinforcements have turned a good lineup into one of MLB’s deepest. Their strikeout-to-walk edge—combined with Kirby’s matchup history—makes Mariners moneyline at –259 the clear lean. My projection: a 5–2 Seattle win.
With Coors-style scoring usually absent at home and Kirby limiting walks, the total of 7.5 falls in favor of the over, but not by much—my projected total is 8 runs.
Find up-to-date model projections and recommended plays in our MLB betting advice section.
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