Seattle Mariners vs San Diego Padres Picks and Predictions August 26th 2025

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The San Diego Padres will visit the Seattle Mariners at T-Mobile Park. The Padres have a record of 74-57 and are ranked second in the NL West. They recently lost their last game and are 5-5 in their last 10 games.

The Mariners hold a 70-61 record and are also ranked second in their division, the AL West. They won their last game but have struggled recently, going 3-7 in their last 10 games. The game will feature starting pitchers Dylan Cease for the Padres and Luis Castillo for the Mariners. The game is scheduled for Tuesday, August 26, 2025, at 9:40 PM.

Padres vs Mariners Key Information

  • Sport: Baseball
  • Teams: San Diego Padres vs. Seattle Mariners
  • Venue: T-Mobile Park in Seattle, WA
  • Date: Tuesday, August 26, 2025
  • Betting Odds: Padres Moneyline -102, Mariners Moneyline -116

The Padres Can Win If…

The San Diego Padres recently played against the Los Angeles Dodgers, losing 8-2. In that game, Nick Pivetta pitched well, going six innings and allowing only two runs. Elias Díaz hit a home run, showing some power at the plate.

The Padres have strong pitching stats that could help them win. They have the second-best ERA in the league at 3.55 and lead in batting average against at .222. Their pitching staff also ranks seventh in strikeouts, which can be key in controlling the game.

Manny Machado is a key player for the Padres with a .292 batting average and 21 home runs. Ramón Laureano also contributes with a .298 average and 19 home runs. With Dylan Cease on the mound, the Padres have a chance to take control early against the Mariners.

The Mariners Can Win If…

The Seattle Mariners enter their next game with momentum from a recent 11-4 win against the Athletics. Logan Gilbert was impressive on the mound with 13 strikeouts over six innings. Cal Raleigh led the offense with two home runs and four RBIs, showing why he is a key player for Seattle.

The Mariners have strong stats that support their chances of winning. They rank 3rd in home runs with 186 and 4th in stolen bases with 132. Their pitching staff has also been reliable, ranking 6th in quality starts with 54 this season.

With Luis Castillo starting, the Mariners have a solid chance to control the game. Castillo has a 3.57 ERA and has shown the ability to keep opposing hitters in check. Seattle’s lineup, featuring power hitters like Eugenio Suárez and Cal Raleigh, can provide the run support needed for a win.

The Lean

The Padres are slightly favored on the moneyline at -102 against the Mariners at -116. My model projects the Padres to win with a score of 4-3. The Padres have a better batting average and on-base percentage, which gives them an edge in this game.

The total for the game is set at 7.5 runs, with the over at -116 and the under at -104. My model projects a total of 7 runs. Both teams have strong pitching, with the Padres having the second-best ERA in the league. This suggests the under is a good pick for this game.

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Raleigh Reaches Historic Milestone

The Seattle Mariners’ playoff push has been fueled by the bat of Cal Raleigh, who crushed his MLB-leading 50th home run of the season in Monday’s 9-6 win over the San Diego Padres. Raleigh became the first catcher in league history to hit 50 homers in a single season and joined Ken Griffey Jr. as the only players in franchise history to reach the mark.

The win also secured the inaugural Vedder Cup for Seattle, a rivalry series officially recognized this season between the Mariners and Padres. For fans tracking standout player milestones and team momentum shifts, stay updated with the latest MLB picks

The Vedder Cup Adds Flavor to the Rivalry

The Vedder Cup trophy is unlike any in sports — a 1963 Fender Telecaster guitar modeled after the one Pearl Jam frontman Eddie Vedder plays. After Monday’s victory, Raleigh strummed the strings before celebrating with his teammates.

The trophy, delivered to Seattle by Pearl Jam’s longtime equipment manager George Webb, was designed with the idea that it should be played, not displayed. With the Mariners now 4-0 against San Diego this year, the cultural ties between the two West Coast clubs are adding an extra spark to the late-season push. Dive deeper into upcoming series previews with our full MLB game breakdowns

Mariners’ Balanced Attack

While Raleigh’s historic homer stole the spotlight, Jorge Polanco delivered a strong performance of his own, going 3-for-4 with a double, a homer, and four RBIs. Seattle broke a 4-4 tie with five runs in the fifth inning, showing their ability to score both with power and timely hitting.

Manager Dan Wilson emphasized that balance as a good sign heading into the postseason chase. Fans looking to sharpen their understanding of betting strategies can explore the expert MLB betting guide for insights.

Padres Flash Offense but Fall Short

The Padres didn’t go quietly, hitting four home runs of their own from Gavin Sheets, Jake Cronenworth, Fernando Tatis Jr., and Ramon Laureano. Manager Mike Shildt praised his team’s at-bats early in the game, though San Diego couldn’t sustain that offensive rhythm into the later innings.

For those tracking betting records and handicappers’ performances during these matchups, check the Sports Hub leaderboard to see which experts are finding consistent value.

Cease vs. Castillo Matchup on Deck

Tuesday’s game sets up an intriguing pitching battle. San Diego hands the ball to Dylan Cease (6-11, 4.71 ERA), who has gone 3-1 in August and comes off an 8-4 win over the Giants. Seattle counters with Luis Castillo (8-7, 3.57 ERA), who struggled in his last outing against Philadelphia but owns a 3-3 record and a 3.13 ERA in eight career starts versus San Diego.

With both teams bringing power bats and proven arms, this clash promises fireworks. For those looking to back their predictions with confidence, explore available buy picks and check the most recent MLB results to stay ahead of the action.

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