St. Louis Cardinals vs New York Yankees Picks and Predictions August 15th 2025

St. Louis Cardinals vs New York Yankees August 15th 2025

The New York Yankees visit the St. Louis Cardinals at Busch Stadium on Friday night. The Yankees hold a 64-57 record and sit third in the AL East. They are coming off a loss and have a 4-6 record in their last ten games. Manager Aaron Boone leads the team, with James Rowson as the hitting coach and Matt Blake as the pitching coach.

The Cardinals have a 61-61 record and are fourth in the NL Central. They have lost their last two games and are 5-5 in their last ten. Oliver Marmol manages the team, with Brant Brown as the hitting coach and Dusty Blake as the pitching coach. The game will feature starting pitchers Luis Gil for the Yankees and Andre Pallante for the Cardinals. Weather conditions are expected to be very hot with clear skies.

Yankees vs Cardinals Key Information

• Sport: Baseball
• Teams: New York Yankees vs. St. Louis Cardinals
• Venue: Busch Stadium in St. Louis, MO
• Date: Friday, August 15, 2025
• Betting Odds: Yankees Moneyline -134, Cardinals Moneyline +114, Yankees Runline -1.5 (+121), Cardinals Runline +1.5 (-145), Total Over 9.0 (-105), Total Under 9.0 (-115)

The Yankees Can Win If…

The New York Yankees recently played a series against the Minnesota Twins. In their last game, they fell short, losing 4-1. Cody Bellinger was a bright spot, hitting a home run and driving in the team’s only run. Despite the loss, the Yankees showed strong pitching from Cam Schlittler, who allowed just one run over five innings.

The Yankees have been strong offensively this season. They rank first in both slugging percentage (.446) and home runs (191). This power at the plate gives them a chance to score big and win games. Aaron Judge is leading the charge with a .333 batting average and 38 home runs.

The Yankees’ pitching staff has been effective, holding opponents to a .228 batting average, which ranks second in the league. They have a solid defense behind them, and their pitchers have delivered 40 quality starts. With Luis Gil on the mound, they will look to improve his record and shut down the Cardinals’ lineup.

The Cardinals Can Win If…

The St. Louis Cardinals are looking to bounce back after a tight 6-5 loss to the Colorado Rockies. In that game, the Cardinals showed strong hitting with Lars Nootbaar and Alec Burleson each hitting home runs. Despite the loss, the Cardinals managed nine hits, keeping their offense active.

Throughout the season, the Cardinals have been solid in hitting doubles, ranking 6th in the league. This ability to get extra-base hits can be key in driving in runs. With players like Alec Burleson, who holds a .282 batting average, the Cardinals have the potential to score consistently.

On the mound, Andre Pallante will start for the Cardinals. His ERA of 4.95 shows room for improvement, but his WHIP of 1.37 indicates he can limit base runners. Facing a Yankees starter with an ERA of 7.27, Pallante has a chance to give the Cardinals an edge in this game.

The Lean

The Yankees are favored on the moneyline at -134, while the Cardinals are at +114. The Yankees have a strong on-base percentage and lead the league in home runs. Our model projects the Yankees to win with a score of 6-4. Based on these factors, the recommendation is to pick the Yankees to win straight up.

The total for the game is set at 9.0, with the over at -105 and the under at -115. The Yankees’ high slugging percentage and the Cardinals’ lower pitching ranks suggest a high-scoring game. Our model projects a total score of 10 runs. Therefore, the recommendation is to take the over on the total.

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Yankees Looking for Hot Stretch Entering Set with Cardinals

The New York Yankees are aiming to find their stride again in the tight American League wild-card race. After a stretch of seven losses in nine games, they stabilized with two wins in three contests against the Minnesota Twins. Now, they head to Busch Stadium for a three-game road series against the St. Louis Cardinals, starting Friday night.

One storyline to watch is the status of first baseman Paul Goldschmidt, who is questionable due to a sprained right knee. The former Cardinals star had been eager to face his old team but may be sidelined for the opener.

“I don’t think it’s anything long-term,” Goldschmidt said. “If it is short-term, I feel really good about that.”

Goldschmidt has posted a .276/.331/.422 slash line since joining the Yankees. His presence has been key both offensively and defensively.

“He’s been a huge part of this team,” Yankees outfielder Cody Bellinger said. “He’s a vacuum at first base and gives us quality at-bats every night.”

Projected Pitching Matchup – Game 1

Luis Gil will be making his third start since returning from a high-grade lat strain. He showed improved command against Houston, allowing just two runs on six hits with seven strikeouts. Yankees manager Aaron Boone praised his balanced use of fastball, changeup, and slider.

For St. Louis, Pallante looks to rebound from a rough outing against the Cubs, where he struggled with both location and pitch effectiveness. The right-hander has yet to start against New York but has logged 4 2/3 scoreless innings in relief appearances.

Team Trends & Standings Impact

The Cardinals are coming off a disappointing series loss to the Colorado Rockies, while the Yankees see this set as a chance to gain ground. St. Louis is expected to get Willson Contreras back in the lineup after a bruised foot kept him out Wednesday.

Fans and bettors alike can track odds and matchup previews through the MLB expert betting guide and monitor live MLB scores as the series unfolds.