Cleveland Cavaliers vs Los Angeles Clippers Picks and Predictions November 23rd 2025

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Cleveland Cavaliers vs Los Angeles Clippers Betting Preview

The Cleveland Cavaliers host the Los Angeles Clippers at Rocket Arena in Sunday NBA action. Cleveland enters at 11-6 after a strong win over Indiana, while Los Angeles sits at 5-11 but snapped a three-game skid behind James Harden’s franchise-record 55 points. Bettors will weigh the Cavs’ home dominance against Harden’s vintage scoring explosion.

Line Movement and Odds

  • Cavaliers Spread: -9.5 (-110)
  • Clippers Spread: +9.5 (-111)
  • Cavaliers MoneyLine: -403
  • Clippers MoneyLine: +314
  • Total: 229.5 (Over -110, Under -110)

Cleveland opened as heavy home favorites, reflecting their strong record and the Clippers’ road struggles. See full NBA odds for market movement.

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Matchup Breakdown

Los Angeles Clippers Outlook

James Harden tied Kobe Bryant for third-most 50-point games in NBA history with his 25th, scoring 55 against Charlotte. He shot 65% from the field and 62% from deep, showing elite efficiency. Chris Paul added a milestone with his 6,000th rebound, cementing his Hall of Fame résumé. The Clippers rank mid-pack in shooting efficiency but rely heavily on Harden’s production. If he continues his hot streak, Los Angeles can keep pace with Cleveland’s offense.

Cleveland Cavaliers Outlook

Donovan Mitchell scored 32 points with nine rebounds against Indiana, while Darius Garland returned with 20 points and seven assists. Garland’s presence stabilizes the backcourt, giving Cleveland one of the league’s most dynamic guard duos. Evan Mobley added 22 points and 12 rebounds, showcasing frontcourt balance. The Cavs average nearly 120 points per game and lead the NBA in three-point attempts, ranking fourth in makes. Their depth and home-court advantage make them tough to beat.

Key Matchup / Path to Victory

The Clippers must ride Harden’s scoring and hope for secondary contributions from Paul George and Kawhi Leonard. The Cavaliers need Mitchell and Garland to control tempo while Mobley anchors the paint. Three-point shooting volume and defensive rebounding will be decisive in this East vs West clash.

Injuries / Availability

Los Angeles lists no major new injuries, with Harden and Paul healthy. For full player status, check the Clippers injury report.

Cleveland lists Jaylon Tyson (concussion) recently returned, while Garland is back from a toe injury. See the Cavaliers injury page for latest updates.

Environment

The game tips at Rocket Arena, where Cleveland is 7-2 at home. Los Angeles is 2-8 on the road, struggling to find consistency away from Crypto.com Arena. Expect a high-energy crowd backing the Cavs’ guard duo against Harden’s scoring showcase.

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Best Bets and Prediction

Projected Final Score: Cavaliers 123, Clippers 112

  • Best Bet: Cavaliers -9.5 (-110)
    Cleveland’s balanced offense and home dominance make them strong favorites to cover.
  • Total: Over 229.5 (-110)
    Our model projects 235 points, leaning over given both teams’ offensive firepower.

Cleveland’s depth and guard play should secure the win, while Harden’s brilliance keeps the Clippers competitive. Expect a high-scoring game trending over the total.

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