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San Antonio Spurs vs Los Angeles Lakers Betting Preview
San Antonio returns home facing uncertainty around Victor Wembanyama’s availability. The Spurs dropped a 106-105 decision in Memphis on Tuesday despite Wembanyama’s return from injury, where he scored 30 points in limited minutes off the bench. Execution and late-game focus proved costly, and the Spurs now turn quickly to a Lakers team trending up.
Los Angeles arrives after a 111-103 win in New Orleans. Luka Doncic and LeBron James carried the offense again, but the supporting cast continues to play a major role. The Lakers have won three straight and four of their last five, even while dealing with injuries to key rotation players.
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Line Movement and Odds
Los Angeles opened -4.5 and has moved to -6, largely tied to uncertainty surrounding Wembanyama on the second night of a back-to-back. San Antonio sits at +6, with bettors waiting on final injury confirmation.
The total opened at 231.5 and has dipped to 229.5, reflecting fatigue concerns and San Antonio’s shortened rotation. Moneyline pricing favors the Lakers, with spread movement tied closely to lineup news.
Track live updates on the NBA odds board.
Matchup Breakdown
San Antonio’s upside depends on Wembanyama. When he plays, the Spurs gain interior scoring, rim protection, and spacing that shifts defensive matchups. Without him, late-game execution and defensive rebounding become major concerns, especially against elite playmakers.
Los Angeles continues to control games through star power and rebounding. Doncic and James create efficient looks, while Deandre Ayton has provided physicality on the glass. The Lakers’ ability to win without full health speaks to improved depth and defensive discipline.
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Injuries and Conditions
San Antonio Spurs
- Victor Wembanyama, knee, questionable
- Devin Vassell, hamstring, probable
See full San Antonio Spurs injury report.
Los Angeles Lakers
- Rui Hachimura, calf, out
- Austin Reaves, calf, out
See full Los Angeles Lakers injury report.
This game is indoors. No weather impact.
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Best Bets and Prediction
Line movement reflects concern over San Antonio’s health and execution. If Wembanyama sits or is limited, the Lakers’ physical edge and playmaking should control the game.
Projected Score: Lakers 118, Spurs 110
Best Bet: Lakers -6
Secondary Lean: Under 229.5
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