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The Angels head to Wrigley Field on Monday night at 2-2 after splitting a four-game set in Houston, while the Cubs are 1-2 after dropping two of three to Washington. First pitch is set for 7:40 p.m. ET in Chicago, with Ryan Johnson lined up for Los Angeles and Edward Cabrera set to make his Cubs debut. The early market has Chicago as a clear home favorite, and that makes sense given the starting-pitching edge and the current lineup context on both sides. This game also comes with the usual Wrigley warning label. Conditions are expected to be warm, around 72 degrees, with wind near 10 mph, so it is not one of those extreme Chicago weather spots where the

Tampa Bay heads into Milwaukee on Monday night trying to build off its first win of the season after salvaging the finale in St. Louis with an 11-7 outburst. The Rays are 1-2, the Brewers are 3-0 after sweeping the White Sox, and this opener at American Family Field feels like a good early test for both lineups because each team showed real life with the bats over the weekend. First pitch is set for 7:40 p.m. local time, with Nick Martinez starting for Tampa Bay and Kyle Harrison making his Brewers debut. Milwaukee probably has the cleaner overall setup. The Brewers outscored Chicago 29-10 in their opening sweep, and even Sunday’s game, where they fell behind big early, turned

The Mets head to Busch Stadium on Monday night with a 2-1 record after dropping the series finale in Pittsburgh, while the Cardinals also sit at 2-1 after losing 11-7 to Tampa Bay on Sunday. First pitch is set for 7:45 p.m. local time in St. Louis, and the probable starters are Clay Holmes for New York and Kyle Leahy for St. Louis. The market has the Mets as a moderate road favorite, with the total mostly sitting between 8.5 and 9.0. This is an interesting early-season matchup because both teams have shown enough offense to matter, but they have gotten there in different ways. New York has looked steadier overall, with a more balanced profile through the first series,

Boston heads to Houston on Monday night trying to stop a two-game skid after dropping the final two games in Cincinnati. The Red Sox are 1-2 and still looking for some lineup stability without Triston Casas, while the Astros come in 2-2 after taking the final two games of their opening series against the Angels. First pitch is set for 8:10 p.m. ET at Daikin Park, with Ranger Suárez making his Boston debut against Lance McCullers Jr. in his first regular-season start since 2021. This is a pretty interesting early spot because both teams have clear strengths and obvious risk points. Boston’s pitching has looked sharper than Houston’s through the first few games, but the Astros have the more dangerous