Duke Blue Devils vs Florida Gators Picks and Predictions December 2nd 2025

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Game Preview: Duke Blue Devils @ Florida Gators

The Duke Blue Devils will face their toughest home test yet as they welcome the defending national champion Florida Gators to Cameron Indoor Stadium on Tuesday in the ACC/SEC Challenge. Both top-10 programs have tested themselves early, but this matchup may reveal even more about their postseason potential.

Duke enters at 8-0 with neutral-court wins over Texas, Kansas, and Arkansas. Florida sits at 5-2 with early losses to Arizona and TCU, but they bounced back last week with a win over Providence. It’s a Final Four rematch that never happened last March and now headlines one of the season’s premier early non-conference clashes.

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Odds and Key Information

LineConsensus Market
SpreadDuke -5.5
MoneylineDuke -220, Florida +180
Total (Over/Under)148.0
Game Time9:00 PM ET, Tuesday, Dec. 2
VenueCameron Indoor Stadium, Durham, NC

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Duke Outlook

The Blue Devils remain unbeaten and are quickly maturing into one of the most complete teams in the country. Their 8-0 start includes wins over three high-major opponents, with the most recent being a comeback victory against Arkansas on Thanksgiving.

Cameron Boozer is the focal point, but Duke’s recent wins have showcased the depth of their rotation. Caleb Foster had 15 points and 8 assists against Arkansas, while freshman Nikolas Khamenia continues to carve out meaningful minutes in high-leverage spots.

Jon Scheyer’s squad is averaging 81.1 points per game and allowing just 64.5. Duke’s balanced scoring and defensive intensity have helped them outscore opponents by nearly 17 points per game.

With home-court advantage at Cameron and growing lineup chemistry, Duke appears ready to rise to another level.

Explore roster breakdowns and metrics at NCAAB teams.

Florida Outlook

The defending national champions are not easing into their new campaign. The Gators dropped a tight opener to Arizona and another tough battle to TCU, but they’ve shown flashes of their upside, particularly in their win over Providence.

Thomas Haugh leads the team with 17.9 points per game, while Xaivian Lee had a 20-point breakout vs Providence. Lee has struggled from deep (21.6% 3PT), but his ability to create shots adds critical spacing for the Gators’ half-court sets.

Florida ranks 23rd nationally in rebounding margin and has held opponents to 41.3% shooting. However, defensive lapses against strong backcourts have been exposed—something Duke’s guards are well-equipped to exploit.

Florida is 2-0 vs ACC teams this season but must improve perimeter shooting (28.2% from deep) to keep pace with Duke.

Full stats available on the NCAAB teams section.

Key Matchup Table

CategoryAdvantage
Scoring DepthDuke
Shooting EfficiencyDuke
Interior DefenseFlorida
Turnover MarginEven
Bench ImpactDuke

The guard matchup between Lee and Foster is pivotal. Florida must also contain Boozer inside while staying competitive from deep.

Betting Trends

  • Duke is 7-1 ATS in its last 8 home games.
  • The total has gone Over in 4 of Duke’s last 6 non-conference games.
  • Florida is 3-6 ATS in its last 9 road games vs ranked teams.
  • The total has gone Under in 5 of Florida’s last 8 games overall.
  • Florida is 2-0 ATS vs ACC teams this season.
  • Duke has covered 5 of its last 6 games when favored by fewer than 6 points.

Get more data-driven betting angles at NCAAB picks.

Prediction

Florida’s title defense has had moments of concern, particularly against high-scoring opponents, and their perimeter shooting continues to lag. Duke’s evolving lineup, home-court edge, and depth make them tough to beat in Durham.

If Foster and Boozer continue their production and Duke defends the paint effectively, the Blue Devils should cover. Florida must control tempo, win on the glass, and hope for an above-average shooting night to pull off the upset.

Projected Score: Duke 78, Florida 70
Spread Pick: Duke -5.5
Total Lean: Under 148.0

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