Kentucky Wildcats vs Loyola Maryland Greyhounds Picks and Predictions November 21st 2025

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Game Preview Kentucky Wildcats @ Loyola (Maryland) Greyhounds

Kentucky returns home aiming to regain stability after a rocky start to its nonconference schedule. The Kentucky Wildcats enter at 3–2 after consecutive losses to Louisville and Michigan State, with injuries and rotational disruptions slowing early-season momentum. Despite high expectations for a roster built around Otega Oweh and a high-tempo offensive model, the Wildcats have yet to demonstrate consistency on the defensive end.

Kentucky’s underlying metrics still show a capable team. The Wildcats score 87.4 points per game, shoot 49.2 percent from the field, and limit opponents to 37.7 percent shooting. Yet the group struggles defending the perimeter, a flaw that Michigan State exploited by converting 11 three-pointers. These issues have pushed bettors to track market adjustments across the NCAAB odds and scores boards while comparing broader team context through the NCAAB teams index.

Loyola (Maryland) enters at 2–4 after dropping three of four, but the Loyola (Maryland) Greyhounds bring a capable backcourt and enough scoring depth to challenge defensive lapses. Their recent loss to Duquesne showcased efficient shooting but highlighted major rebounding and defensive limitations. The Greyhounds frequently allow opponents to exceed shot-quality expectations, a concern against a Kentucky team that generates high-percentage looks in transition.

This matchup presents an opportunity for Kentucky to correct defensive structure and stabilize rotations. It also serves bettors who compare performance tiers across futures markets such as the College Basketball Championship odds and player-oriented projections outlined in the John Wooden Award odds and predictions. Those evaluating pace and efficiency angles may also lean on concepts explored within the NBA expert betting guide.

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Odds and Key Information

Kentucky projects as a sizeable home favorite. Market position across the NCAAB odds and scores section reflects the Wildcats’ significant talent and athletic advantage. The total is expected to fall in a higher range due to pace projections and the defensive variance shown by both teams.

Key points impacting the early line:

• Kentucky averaging 87.4 points per game.
• Wildcats allowed 96 and 83 points in their last two losses.
• Loyola MD allows high shooting percentages, especially off screens.
• Greyhounds produce enough backcourt scoring to extend possessions but struggle in physical matchups.

Bettors comparing sides and totals often reference the analytical breakdowns within the NCAAB picks hub for further clarity.

Kentucky Wildcats Outlook

The Kentucky Wildcats maintain strong offensive indicators despite recent setbacks. Denzel Aberdeen leads Kentucky with 14.2 points per game, while Otega Oweh adds 12.8. Malachi Moreno contributes 6.8 rebounds, providing interior reliability, and Jasper Johnson generates 3.2 assists.

Kentucky shoots efficiently inside the arc but remains inconsistent from three at 31.9 percent. Defensively, the Wildcats have struggled to communicate in transition and have allowed opponents to produce efficient catch-and-shoot opportunities. Their most recent defeat to Michigan State reflected stretched defensive assignments and sluggish closeouts.

Even with the issues, Kentucky’s roster composition strongly favors high-possession games against mid-major opponents. Oweh’s athleticism and Aberdeen’s shot creation anchor an offense capable of overwhelming smaller rotations.

Injury Report

Kentucky continues to manage injuries that affect rotation predictability but not its overall availability of core contributors.

Loyola (Maryland) Greyhounds Outlook

The Loyola (Maryland) Greyhounds bring competitive guard play but inconsistent defensive structure. Their recent 92–78 loss to Duquesne included 48.3 percent shooting but only 61.9 percent at the line and a sizable rebounding deficit.

Jacob Theodosiou leads Loyola with 17.2 points per game and has surpassed 20 points in three of six games. His shot creation and volume scoring make him Loyola’s primary offensive weapon. Braeden Speed adds 13.7 points and a team-leading 3.3 assists, providing complementary backcourt efficiency.

Loyola’s depth is functional, and coach Josh Loeffler emphasizes rotational flexibility. However, the team’s defensive liabilities and limited size create structural issues against high-major frontcourts. Their profile suggests challenges absorbing Kentucky’s pace and physicality for a full 40 minutes.

Injury Report

Loyola MD expects to have its main rotation available, though frontcourt size remains a concern.

Key Matchup Table

Matchup AreaAdvantage
Offensive efficiencyKentucky
ReboundingKentucky
Backcourt scoringLoyola MD
Transition defenseKentucky

Betting Trends

• Kentucky overs have been common due to defensive inconsistency.
• Wildcats have struggled to meet expectations when laying double-digit spreads.
• Loyola MD allows high-quality perimeter looks.
• Greyhounds overs frequently connect in guard-driven matchups.
• Kentucky is due for positive shooting regression from deep.

Additional angles and analytics appear across the NCAAB picks and updated movement on the NCAAB odds board.

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Predictions

Kentucky faces a favorable matchup, particularly through transition scoring and half-court spacing. Loyola MD may generate competitive stretches behind its guards, but rebounding and defensive challenges are likely to widen the margin as possessions accumulate. Expect Kentucky to apply steady pressure, create turnovers, and convert consistent high-percentage opportunities.

Projected Score: Kentucky 89, Loyola MD 71
Spread Pick: Kentucky to cover
Total Lean: Over

Why You Need Expert Picks

Games featuring large spreads and volatile defensive profiles require modeling that goes beyond traditional box-score analysis. Expert insights integrate tempo projections, efficiency splits, and matchup-specific trends. Bettors seeking validation for sides or totals rely on accurate records and modeling found through the Handicappers Leaderboard inside the NCAAB picks section, where curated evaluations filter value from noise.