Missouri Tigers vs Oklahoma Sooners Picks and Predictions January 24th 2026

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Oklahoma Sooners head to Columbia to take on the Missouri Tigers at Mizzou Arena on Saturday, with tipoff scheduled for 2:00 PM ET. This SEC matchup pits two mid-tier programs trying to claw their way into better tournament seeding range. Missouri has started to find rhythm at home and is listed as a -4.5 favorite. Oklahoma, still searching for consistency on the road, enters as a +175 underdog on the moneyline. The total is set at 150.5, and pace may be the deciding factor on both side and Over/Under outcomes.

Oklahoma vs Missouri Odds

Below are the current lines for this SEC showdown. As always, keep checking the latest college basketball odds for line movement or injury-related shifts.

TeamMoneylineSpreadTotal
Oklahoma+175+4.5 (-108)O 150.5
Missouri-224-4.5 (-117)U 150.5

Oklahoma Betting Form

The Oklahoma Sooners have shown flashes this season but continue to struggle with consistency, especially in true road environments. They’re 2–4 on the road and have failed to cover in four of those games. The Sooners play with solid tempo and spacing, but they often stall in half-court offense when their guards aren’t initiating cleanly.

Offensively, they’ve leaned heavily on pick-and-roll action and ball reversals to generate open threes and dribble penetration. They’re above-average from the perimeter and solid from the line, but their midrange inefficiency holds them back. More concerning is their defensive profile: Oklahoma ranks below the SEC average in rim protection and has been vulnerable to teams that attack downhill.

They’ll need to keep this game in transition where they have an athleticism edge. If this slows into a half-court grind, they’ll have trouble matching Missouri’s physicality and paint scoring. One wildcard is bench production—Oklahoma has some depth, but it hasn’t been reliable from game to game. Availability is worth tracking here, so check the Oklahoma injury report for any late movement or rotations shifts before betting.

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Missouri Betting Form

The Missouri Tigers are starting to click—especially at home, where they’ve won five straight and covered four. Their offense revolves around inside-out play, and they’ve been much more effective shooting the ball at Mizzou Arena. This team thrives on energy, and their starters feed off the home crowd early.

They’re not fast, but they’re efficient. Missouri gets good looks inside and ranks among the SEC leaders in free-throw rate. They don’t turn the ball over much and force opponents into physical matchups in the paint. The three-point shooting is streaky, but they’ve shown the ability to knock down timely shots to break open tight games. On the defensive end, they’re better than the metrics suggest. They rotate well and crash the glass hard—especially in the second half.

Foul trouble has been an issue in a few spots, but their rotation has settled recently, and key players are logging consistent minutes. They’ve avoided major injuries this season, but you’ll still want to confirm status updates on the Missouri injury report before locking in any side or total.

Oklahoma vs Missouri Matchup Breakdown

This game comes down to two big swing factors: tempo and shot location. Oklahoma wants pace—they’ll try to create run-outs and early looks, particularly in secondary transition. Missouri is more deliberate and built to win half-court matchups. Whichever team imposes their pace early could dictate how the spread and total both play out.

On the glass, Missouri has the advantage. They rebound well on both ends and have the kind of frontcourt size that has given Oklahoma issues. The Sooners struggle when forced into a second shot contest, and their transition defense hasn’t been sharp in recent road games. Missouri should be able to earn extra possessions here and get into the bonus early if they stay aggressive.

Turnover margin is fairly even, but Missouri’s ball security has been better recently. Oklahoma gambles on defense to create turnovers, but when those risks don’t pay off, it leads to easy buckets the other way. That could be a problem in a game where points at the rim will be key.

If you’re building a betting model for matchups like this, our college basketball betting guide digs into how pace, rebounding, and late-game foul factors impact both spread and totals markets in SEC games.

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Oklahoma vs Missouri Predictions and Best Bets

Missouri -4.5 is the right side here. They’re playing their best basketball of the season, have been sharp at home, and their physicality in the paint is a tough matchup for an Oklahoma team that struggles to defend the rim. The Sooners are live if they shoot well early, but their road form doesn’t justify a strong play. This is a spot where Missouri’s size, rebounding, and half-court control should pay off—especially late.

The total at 150.5 is interesting. It sits in a tough zone—both teams are capable of 75+ points, but that assumes both sides shoot well. Missouri has been slowing tempo when ahead, and Oklahoma tends to stall in half-court sets. Slight lean to the Under, based on Missouri’s ability to control the pace and limit second-chance scoring.

If you’re looking for a bonus angle, Missouri first-half -2 or -2.5 is worth a look. They’ve come out hot at home and Oklahoma’s had slow starts on the road all season.

Best Bet: Missouri -4.5 (-117).

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