Pittsburgh Panthers vs Ohio State Buckeyes Picks and Predictions November 28th 2025

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Game Preview: Ohio State Buckeyes @ Pittsburgh Panthers

The undefeated Ohio State Buckeyes hit the road for the first time this season as they travel to face the Pittsburgh Panthers on Friday at Petersen Events Center. This matchup offers the Buckeyes a chance to open the season 7-0 for the first time since 2019, while Pitt looks to recover from a disappointing home loss to Quinnipiac. With Ohio State opening as a 5.5-point favorite and bettors reviewing broader NCAAB lines through the college basketball odds board, this matchup shapes up as a key early-season test for both programs.

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Ohio State’s 113-60 demolition of Mount St. Mary’s showcased their offensive explosiveness and depth, prompting coach Jake Diebler to credit his team’s execution and defensive focus. Led by Bruce Thornton and John Mobley Jr., the Buckeyes enter with top-five national efficiency numbers and with a clear motivation to avenge last year’s 91-90 overtime loss to Pitt. For returning players, Diebler acknowledged that the revenge element naturally exists, adding to the emotional weight of the matchup.

Pitt, meanwhile, comes off one of its most disappointing performances in recent memory. The Panthers surrendered 57 percent shooting to Quinnipiac and were blitzed from the perimeter in an 83-75 home loss. Jeff Capel criticized his team’s defensive detail and energy, pointing to breakdowns in ball-screen coverage and gap defense. With a 4-1 home mark, the Panthers now look to regain balance in their first high-major home matchup of the season, a theme explored frequently in the NCAAB previews hub.

Odds and Key Information

Ohio State sits as a -5.5 road favorite with a total at 146.5. The Buckeyes’ early-season scoring profile—over 92 points per game—has pushed bettors toward the over, while Pitt’s defensive inconsistency further contributes to that market lean. Pitt’s +202 moneyline has attracted mild support due to their home results, but sharp interest remains primarily on Ohio State due to shooting margins and efficiency differentials.

With the game televised on ESPN, the profile of this matchup aligns with several high-interest early-season contests tracked in the college basketball scores and odds section.

Ohio State Buckeyes Outlook

Ohio State’s 6-0 start has come through a blend of elite scoring and improved defensive communication. Diebler’s group has emphasized ball movement and push-ahead tempo, and their 53.8 percent field-goal mark ranks near the top nationally. The Buckeyes also hold the best two-point percentage in the country at 67.4 percent, reflecting their ability to generate high-quality looks at the rim through Thornton’s driving and Mobley’s shot creation.

Thornton’s 21 points per game and Mobley’s 16.8 scoring average form one of the nation’s best backcourt tandems. Their efficiency has been central to Ohio State’s scoring surge. With the Buckeyes ranking top-30 nationally in scoring and moving quickly in predictive metrics highlighted throughout the NCAAB team index, their offensive consistency remains a defining advantage.

On defense, Ohio State has tightened rotations and improved ball-screen discipline. Their win over Notre Dame demonstrated late-game poise, something that should matter in a challenging road atmosphere. Ohio State’s depth extends through strong bench productivity, a component that has bolstered their spread reliability—an aspect bettors analyze frequently on the NCAAB picks page.

To win, Ohio State must maintain pace, attack Pitt’s inconsistent closeouts and force the Panthers into late-clock possessions.

Pittsburgh Panthers Outlook

Pitt enters at 4-3 and searching for a stabilizing win. Their loss to Quinnipiac exposed defensive gaps that Capel deemed unacceptable, from ball pressure to interior rotations. The Panthers allowed over 57 percent shooting and nearly 65 percent from deep, a performance far below their standard. Capel’s frustration centered on effort level and preparation, warning that the issues began hours before tipoff during shootaround.

Still, Pitt remains 4-1 at home. Cameron Corhen leads with 14.3 points per game, and Brandin Cummings provides secondary scoring at 12.4 per contest. The Panthers rebound well (38 per game) and shoot 35 percent from three, offering enough firepower to challenge Ohio State if defensive focus improves.

Their transition defense must improve significantly, as the Buckeyes thrive when forcing quick mismatches. Pitt’s scoring droughts have been noticeable in losses, an issue frequently highlighted across efficiency dashboards in the NCAAB previews portal. Their best path to an upset comes through disrupting Ohio State’s rhythm, protecting the arc and controlling defensive glass.

Key Matchup Table

CategoryOhio State BuckeyesPittsburgh Panthers
Record6-04-3
Offensive Strength92.5 PPG; 53.8 FG%; 67.4% on 2PT72.1 PPG; 35.2% from three
Key ScorersThornton 21 PPG; Mobley 16.8 PPGCorhen 14.3 PPG; Cummings 12.4 PPG
DefenseImproved ball-screen disciplineAllowed 83 to Quinnipiac; perimeter issues
ReboundingBalanced team effort38 RPG; strong home presence
IntangiblesRoad debut; revenge motivationBounce-back spot at home

Betting Trends

Ohio State is undefeated straight up and perfect as a favorite, covering in half of its games. Their elite scoring efficiency has made them a frequent over candidate, supported by their pace and finishing ability. Pitt’s home performance remains their strongest angle at 4-1, though recent defensive volatility complicates projections. Bettors comparing metrics across similar matchups through the college basketball odds hub will find Ohio State’s statistical margin notably stronger.

The Lean

Ohio State’s offense has consistently generated scoring runs that opponents struggle to counter. Pitt’s defensive breakdowns against Quinnipiac raise concerns about their ability to slow the Buckeyes’ high-end backcourt production. While Pitt’s home court offers stability, Ohio State’s efficiency, depth and scoring reliability create a clear analytical edge.

Projected Score: Ohio State 82, Pittsburgh 72
Best Spread Pick: Ohio State -5.5
Total Lean: Over 146.5

For additional perspective on similar early-season matchups, bettors often explore the rotating breakdowns published in the NCAAB previews hub, especially in games featuring elite offensive efficiency.

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