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Game Preview San Francisco @ Colorado
The San Francisco Dons (5-1) face off against the Colorado Buffaloes (5-0) in the opening round of the Acrisure Holiday Classic on Thursday, November 27, 2025, at 2:00 p.m. ET. The neutral-site clash at Acrisure Arena in Palm Desert, CA features two teams off to impressive starts.
San Francisco enters with momentum after defeating Minnesota 77-65 behind a balanced attack and 24 points from Ryan Beasley. Meanwhile, Colorado has yet to leave Boulder this season but boasts an undefeated record, most recently putting up 95 points in a dominant win over UC Davis.
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Odds and Key Information
Spread: San Francisco -1.5
Total: 151.5
Moneyline: San Francisco -119, Colorado -105
Venue: Acrisure Arena (Neutral Site)
TV: CBSS
Track all NCAAB odds and scores leading into tip-off.
San Francisco Outlook
San Francisco’s success has come from its efficient offense and team depth. The Dons rank 17th nationally in three-point shooting percentage (41.2%) and post a stellar 57.7% effective field goal percentage. Ryan Beasley leads the team in scoring at 16.0 points per game, but he’s supported by a core including Mookie Cook (13.3 PPG), Tyrone Riley IV (11.2 PPG), and 6-foot-9 forward David Fuchs (10.3 PPG).
Against Minnesota, the Dons had five players in double figures and shot 61.5% from the field. Fuchs hit a key three late in the game, showcasing his shooting range. San Francisco is 4-0 at home and 1-1 away, but their scoring depth makes them a threat on neutral courts as well.
If you’re considering backing the Dons, understanding alternate total points may open up more value.
Colorado Outlook
Colorado’s offense has been one of the most efficient in the country, averaging 94.4 points per game (13th nationally) and hitting 53.4% from the field (8th). Their high-tempo offense is balanced, with five players averaging double figures, led by Sebastian Rancik and Isaiah Johnson at 14.8 PPG each.
Point guard Barrington Hargress, a transfer from UC Riverside, has impressed with 28 assists and just 5 turnovers (5.6 AST/TO ratio), which ranks among the best in the Big 12. The Buffaloes also draw plenty of fouls and convert at the line, averaging 24.6 made free throws per game.
Colorado has covered the spread in 60% of their games. Bettors looking to explore risk mitigation may benefit from this guide on hedge bets.
Key Matchup Table
| Key Stats | San Francisco Dons | Colorado Buffaloes |
|---|---|---|
| Points Per Game | 80.7 | 94.4 |
| FG % | 48.9% | 53.4% |
| 3PT % | 41.2% | 38.7% |
| Free Throws Made/Game | 17.2 | 24.6 |
| Turnover Margin | +1.1 | +2.4 |
Betting Trends
San Francisco is 4-2 ATS this season and has hit the OVER in 3 of their last 5. Colorado, undefeated at 5-0, has covered in 3 of 5 games, also favoring the OVER in recent performances.
Both offenses are top-tier in efficiency and scoring volume, pointing to possible value in total points markets. If you’re considering parlay options or alternate spreads, our guide on what is a parlay bet can help inform your approach.
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Predictions
This matchup features two offensively gifted teams, but Colorado’s scoring efficiency, tempo, and elite guard play may give them the edge, especially in transition and at the free-throw line. San Francisco’s shooting can keep it close, but Colorado’s experience and poise in late-game situations could prove decisive.
Projected Score: Colorado 92, San Francisco 90
Pick Against the Spread: Colorado +1.5
Lean on Total: OVER 151.5
Why You Need Expert Picks
With tournament-style neutral-site games, unpredictable outcomes are common. That’s why it’s critical to rely on expert insights from our NCAAB picks and Handicappers Leaderboard for betting confidence.
Make informed plays by exploring topics like live betting, moneyline betting, or how the spread works. Dive deeper into market options with props betting and teaser strategies.
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