Vanderbilt Commodores vs Eastern Kentucky Colonels Picks and Predictions November 12th 2025

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Game Preview: Vanderbilt Commodores vs Eastern Kentucky Colonels

The Vanderbilt Commodores will look to extend their perfect start when they host the Eastern Kentucky Colonels on Wednesday, November 12, 2025, at Memorial Gymnasium in Nashville. Vanderbilt’s shooting efficiency has been the story of its season, while Eastern Kentucky enters with a fast-paced offense capable of scoring in bunches.

The Vanderbilt Commodores (2-0) have opened the year by scoring 105 points in consecutive games — the program’s first such streak to begin a season since 1980. Coach Mark Byington’s squad has drained 31 of 67 three-point attempts, ranking among the most accurate perimeter teams in the SEC. Senior Tyler Nickel leads Vanderbilt with 18.5 points per game, supported by guards Tyler Tanner and Duke Miles, both averaging over 15 points.

Byington emphasizes ball movement and unselfish play, and Vanderbilt has responded with efficient offense and turnover creation. The Commodores forced 12 turnovers against UCF, turning those mistakes into 20 points in transition.

The Eastern Kentucky Colonels (1-1) are similarly built on tempo and spacing. They average 100.5 points per game and have hit 25 threes through two contests. Forward Austin Ball leads the team with 16.5 points per game, while Montavious Myrick and Jalen Cooper add balance to a lineup that ranks top 25 nationally in both pace and three-point makes.

For more context on total points markets, read the alternate total points guide.

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Odds and Key Information

MarketOdds
SpreadVanderbilt -29.5 (-110), Eastern Kentucky +29.5 (-110)
Total170.5 (-115 / -105)
MoneylineVanderbilt -50000, Eastern Kentucky +7000
VenueMemorial Gymnasium, Nashville, TN
TimeWednesday, 8:00 PM ET

Vanderbilt opened as a heavy favorite, reflecting its elite efficiency and home-court advantage. The 170.5 total signals the potential for a fast, high-scoring matchup between two top-25 teams in offensive tempo. For odds movement and line shopping resources, check the college basketball odds board.

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Eastern Kentucky Colonels Outlook

Eastern Kentucky’s attack has been dynamic through two games, averaging over 100 points per contest and connecting on 36.8 percent from beyond the arc. The Colonels rely on speed — ranking near the national top 10 in possessions per game — and second-chance scoring from forward Jalen Cooper, who averages 9.5 rebounds.

Their defense, however, remains a concern. Eastern Kentucky allows nearly 48 percent shooting, including 40 percent from three. Against a perimeter-heavy Vanderbilt offense, containing shooters will be the key to staying within the spread.

Montavious Myrick’s leadership and ability to draw contact (averaging six free throw attempts per game) offer some stability in half-court sets. Still, the Colonels must reduce turnovers and limit transition points to avoid falling behind early.

Learn how to evaluate scoring volatility and shot variance in the basketball betting guide.

Vanderbilt Commodores Outlook

Vanderbilt has shown elite offensive efficiency through its opening week. The Commodores are averaging 105.0 points on 55.9 percent shooting, including 46.3 percent from deep. That blend of perimeter and midrange execution has given them the second-highest offensive rating in the SEC.

Duke Miles and Tyler Tanner have formed a balanced backcourt that complements the experience of Nickel and Harris on the wings. Byington’s rotation is also producing defensively — Vanderbilt is averaging 9.5 steals per game and converting turnovers into points at an elite rate.

The Commodores’ floor spacing and movement mirror several advanced offensive principles discussed in the sports betting strategies guide, where shot quality and tempo metrics often determine betting value.

At home, Vanderbilt has covered in both games and outscored opponents by 33.5 points per contest. Their combination of high-volume scoring and consistent shot distribution suggests another strong performance.

Key Matchup Table

CategoryAdvantage
Offensive EfficiencyVanderbilt
Three-Point ShootingVanderbilt
ReboundingVanderbilt
Turnover MarginVanderbilt
PaceEastern Kentucky
Bench DepthVanderbilt
Free-Throw AccuracyEastern Kentucky
Coaching ContinuityVanderbilt

Vanderbilt’s offensive depth and balance give it an edge in nearly every measurable category. Eastern Kentucky’s up-tempo style could help push the total, but Vanderbilt’s shooting discipline and defensive spacing should keep the game under control by halftime.

Betting Trends

  • Vanderbilt is 4-0 ATS in its last four non-conference games.
  • The over is 3-1 in Vanderbilt’s last four home contests.
  • Eastern Kentucky is 6-2 ATS in its last eight road games versus SEC opponents.
  • Commodores are 7-1 straight up in their last eight home games.
  • Under is 5-3 in Eastern Kentucky’s last eight as a double-digit underdog.

For more line comparison tools and public betting data, visit the college basketball picks page.

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Predictions

Vanderbilt’s combination of perimeter shooting, pace control, and home-court strength should lead to another convincing win. Eastern Kentucky’s fast style could generate brief scoring runs, but the Colonels’ defensive gaps likely prevent them from sustaining momentum.

Projected Final Score: Vanderbilt 110, Eastern Kentucky 85
Spread Pick: Eastern Kentucky +29.5
Total Lean: Over 170.5

For more data-driven breakdowns, see the expert betting guide explaining how large spreads interact with pace-driven teams.

Why You Need Expert Picks

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Projected Final: Vanderbilt Commodores 110, Eastern Kentucky Colonels 85
Spread Pick: Eastern Kentucky +29.5
Total Lean: Over 170.5

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