Iowa Hawkeyes vs Penn State Nittany Lions Picks and Predictions October 18th 2025

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Penn State Nittany Lions vs Iowa Hawkeyes Betting Preview

The Penn State Nittany Lions travel to face the Iowa Hawkeyes on Saturday night in a Big Ten matchup filled with emotion and uncertainty. Kickoff is set for 7:30 PM ET at Kinnick Stadium in Iowa City, Iowa, with the game airing on NBC.

Penn State enters the contest in turmoil after firing longtime head coach James Franklin following three consecutive losses, while Iowa looks to stay hot after a dominant shutout victory over Wisconsin.

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Penn State Resets After Coaching Change

The Nittany Lions (3-3, 0-3 Big Ten) have gone from playoff hopefuls to rebuilding mode in a matter of weeks. Their most recent loss, a shocking 22-21 home defeat to Northwestern, was the final straw that ended James Franklin’s 12-year tenure in State College.

Defensive backs coach Terry Smith has taken over as interim head coach, tasked with restoring belief and competitiveness in a team that looks emotionally drained. “We got our coach fired,” senior lineman Nick Dawkins said. “We didn’t do our job well enough, and now it’s on us to respond.”

The timing couldn’t be worse. Starting quarterback Drew Allar suffered a season-ending leg injury in the loss to Northwestern. Redshirt freshman Ethan Grunkemeyer now takes over at quarterback, marking his first career start — and it comes against one of the nation’s stingiest defenses.

Penn State averages 25.7 points per game but has scored only 30 total points across its last two contests. The offense must rediscover its rhythm without Allar, relying on running back Kaytron Allen and receiver KeAndre Lambert-Smith to spark production.

More details and analytics are available on the college football odds page.

Iowa Finds Balance at the Right Time

Iowa (4-2, 2-1 Big Ten) comes into Week 8 with renewed confidence after a 37-0 blowout of Wisconsin. For the first time in years, the Hawkeyes’ offense is complementing their elite defense.

Quarterback Cade McNamara has managed games efficiently, while running back Kaleb Johnson leads a ground attack averaging 172 yards per game. The Hawkeyes’ offense is producing 30.7 points per contest — a significant improvement from the past two seasons when Iowa ranked near the bottom nationally in scoring.

Defensively, Iowa remains one of the toughest teams in college football. The unit allows just 13.0 points per game (5th in FBS) and 268 total yards per game (7th in FBS). Led by linebacker Jay Higgins and cornerback Cooper DeJean, the defense thrives on discipline and takeaway opportunities.

Head coach Kirk Ferentz praised his team’s consistency while refusing to overlook a wounded Penn State. “It’s a really talented football team we’re playing,” Ferentz said. “They’ve had some changes, but we expect their best.”

For model projections and expert picks, visit the college football betting guide.

CFB
2025-10-16 16:30
Open
TULSA
EAST CAROLINA
CFB
2025-10-18 09:00
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GEORGIA TECH
DUKE
CFB
2025-10-18 12:30
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TEXAS A&M
ARKANSAS

Line Movement and Odds

According to the latest college football picks, Iowa opened as a 7.5-point favorite at home with the total set around 44.5. The Hawkeyes’ strong defense and Penn State’s offensive uncertainty have pushed most early money toward the under.

Iowa has covered four straight games at home, while Penn State has failed to cover in three consecutive matchups.

Matchup Breakdown

Penn State Nittany Lions Outlook

With a new head coach and a freshman quarterback, Penn State’s offense will likely simplify its approach. Expect the Nittany Lions to lean heavily on the running game and short passes to control tempo and minimize turnovers.

Defensively, Penn State still has talent. Linebacker Abdul Carter and cornerback Kalen King headline a group allowing just 20.8 points per game despite recent struggles. The key will be stopping Iowa’s rushing attack and forcing McNamara into uncomfortable passing downs.

However, fatigue and morale could play major roles as the team adjusts to life post-Franklin.

Iowa Hawkeyes Outlook

The Hawkeyes’ identity remains centered around defense and field position. McNamara’s efficiency and Johnson’s power running have made the offense less one-dimensional. Iowa’s offensive line has improved significantly, allowing just five sacks through six games.

Special teams remain elite, with kicker Drew Stevens perfect on field goals this year and punter Tory Taylor averaging 47 yards per punt — both critical weapons in Iowa’s conservative game plan.

Key Edge

Iowa’s consistency, defensive discipline, and home-field advantage create a perfect storm against a Penn State team in transition. Unless Grunkemeyer delivers a stunning debut, the Hawkeyes’ defense should control the pace and keep points scarce.

Betting Trends

  • Iowa is 8-1 straight-up in its last nine home games.
  • Iowa is 6-2 ATS in its last eight against Big Ten opponents.
  • Penn State is 1-5 ATS in its last six road games.
  • The under has hit in seven of Iowa’s last nine home games.
Top Winners – Yesterday
Sean Kuchman
$540
2. Info Plays
$285
3. James Acker
$217
4. Evan Lewis
$200
5. Tim Michael
$125
Top Winners – This Week
Computer Picks
$1,000
2. Jacob Hoffman
$808
3. Sean Kuchman
$762
4. Bobby Babowski
$735
5. Ryan Davis
$587
Top Winners – This Month
Sas Insider
$2,255
2. Ryan Davis
$1,440
3. Jimmy Boyd
$1,328
4. Rubi Chavez
$1,269
5. Computer Picks
$1,190

Best Bets and Prediction

This matchup feels like a reset for both programs — but only one is trending upward. Expect Iowa to dominate at the line of scrimmage and force turnovers against an inexperienced Penn State quarterback.

Projected Score: Iowa 27, Penn State 10
Best Bet: Iowa -7.5
Secondary Lean: Under 44.5

For more CFB previews, analysis, and trends, visit ScoresAndStats College Football.