Purdue Boilermakers vs Usc Trojans Picks and Predictions September 13th 2025

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Purdue and Southern California will square off Saturday in West Lafayette as both programs begin their Big Ten schedules. For Boilermakers coach Barry Odom, the game comes with a personal connection — Trojans quarterback Jayden Maiava, who played under Odom at UNLV in 2023.

Maiava was outstanding as a freshman, throwing for more than 3,000 yards while leading the Rebels to nine wins. After transferring to USC, he has quickly taken control of the offense, leading the Trojans to a 2-0 start.

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Maiava’s Impact on USC’s Hot Start

Maiava has been nearly perfect through two starts this season. He has completed 31 of 42 passes for 707 yards, six touchdowns, and no interceptions, while adding a rushing score. His efficiency has powered USC to lopsided wins over Missouri State and Georgia Southern, during which the Trojans combined for 132 points.

The supporting cast has been equally dangerous. Wideout Makai Lemon already has 248 receiving yards and two touchdowns, while four different USC running backs have found the end zone multiple times. Waymond Jordan leads the ground game with an impressive 10 yards per carry.

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Purdue’s Balanced Approach

Purdue has matched USC’s perfect start, opening 2-0 for the first time since 2021. The Boilermakers handled Ball State and Southern Illinois in their first two games, relying on a balanced offensive attack.

Quarterback Ryan Browne has thrown for 481 yards and four touchdowns, while running back Devin Mockobee has rushed for 185 yards and three scores. Odom’s roster overhaul has shown early promise as the team looks to start 3-0 for the first time since 2007.

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Key Defensive Challenge for Purdue

The toughest task for the Boilermakers will be slowing down a USC offense that has steamrolled opponents. Purdue’s defense must contain Maiava’s precision passing while accounting for the Trojans’ depth at running back and wide receiver.

Lincoln Riley, USC’s head coach, praised Purdue’s early progress under Odom, noting the job his staff has done blending new players into the lineup. Still, the Boilermakers’ defense will be tested like never before against one of the nation’s most prolific attacks.

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Betting Perspective

This matchup offers intrigue for both fans and bettors. USC has the firepower to overwhelm opponents, but Purdue carries early-season momentum and the advantage of playing at home.

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