Tulane Green Wave vs Charlotte 49ers Picks and Predictions November 29th 2025

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Tulane Green Wave vs Charlotte 49ers Betting Preview

The Tulane Green Wave host the Charlotte 49ers at Yulman Stadium in Week 14 American Conference action. Tulane enters at 9-2 ranked No. 24 nationally, while Charlotte sits at 1-10 on an eight-game losing streak. Bettors will weigh Tulane’s playoff aspirations against Charlotte’s spoiler hopes in this late-season matchup.

Line Movement and Odds

  • Tulane Spread: -30.0 (-110)
  • Charlotte Spread: +30.0 (-110)
  • Tulane MoneyLine: -9200
  • Charlotte MoneyLine: +2350
  • Total: 53.5 (Over -109, Under -112)

Tulane opened as massive favorites, reflecting their home dominance and Charlotte’s offensive struggles. See full NCAAF odds for market movement.

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Matchup Breakdown

Charlotte 49ers Outlook

Charlotte fell 35-3 to Georgia, with QB Grayson Loftis throwing for 130 yards. WR Javen Nicholas remains a reliable target with 56 catches for 700 yards. The 49ers rank 85th nationally in passing yards (2,305) and have shown defensive playmaking, ranking seventh in fumbles recovered and sixth in interceptions. Their ability to generate turnovers could be their best chance to stay competitive against Tulane.

Tulane Green Wave Outlook

Tulane defeated Temple 37-13, led by QB Jake Retzlaff’s 231 passing yards and a balanced rushing attack. Retzlaff has 2,426 passing yards and 565 rushing yards this season, while WR Shazz Preston has 539 receiving yards. Tulane’s defense ranks top-15 nationally with 26 sacks and 10 interceptions, complementing an offense that has scored 317 points. Their undefeated home record (5-0) underscores their strength in New Orleans.

Key Matchup / Path to Victory

Charlotte must rely on Nicholas and Loftis to stretch Tulane’s secondary while forcing turnovers defensively. Tulane needs Retzlaff’s dual-threat ability and their defensive front to dominate. Ball security and red-zone execution will be decisive in this American Conference clash.

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Injuries / Availability

Charlotte Questionables/Out: Justin Olson (WR, out), Jonny King (OL, questionable), Mason Bowers (OL, questionable), Derrick Edwards (DB, questionable), Andrew Adair (OL, out), Henry Rutledge (RB, out), Conner Harrell (QB, out), Jayden McGowan (WR, out), Boston Brinkley (OL, questionable), Isaiah Bullerdick (OL, out), Ayo Tifase (DL, out), DJ Burgess (DL, out).

Tulane Questionables/Out: Jack Hollifield (OL, questionable), LeRon Husbands (TE, out), Ty Thompson (TE, out), Bryce Bohanon (WR, questionable), Gerrod Henderson (DE, out), Jack Tchienchou (S, questionable), Dorion Jackson (DB, questionable), Dickson Agu (LB, out), Harold Lawson (LB, questionable), Jayden Lewis (DB, questionable), Carson Klein (S, questionable), Cooper Helmke (K, questionable).

Environment

The game kicks at Yulman Stadium, where Tulane is 5-0 at home. Charlotte is 0-4 on the road, struggling to find consistency. Expect a charged atmosphere with Tulane chasing a conference title berth.

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Best Bets and Prediction

Projected Final Score: Tulane 38, Charlotte 14

  • Best Bet: Charlotte +30.0 (-110)
    Charlotte’s strong ATS record on the road (15-5) suggests they can stay within the large spread.
  • Total: Under 53.5 (-112)
    Our model projects 52 points, leaning under given Tulane’s defensive strength and Charlotte’s offensive struggles.

Tulane’s balanced attack and defensive dominance should secure the win, while Charlotte’s turnover creation helps them cover. Expect a decisive Tulane victory trending under the total.

Handicappers and Service Plays

Strengthen your college football betting approach by exploring expert breakdowns in our Best Handicappers, tracking conference trends on the Leaderboard, and reviewing premium NCAAF picks in the Buy Picks section for sharper insights.

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