Game Preview Seattle Seahawks @ Arizona Cardinals
The Seattle Seahawks will host the Arizona Cardinals in Week 10, with both teams trending in opposite directions. Seattle rides a three-game winning streak to reach 6-2, while Arizona sits at 3-5 and continues to fight through injuries at key positions.
Newly acquired wide receiver Rashid Shaheed headlines the story for Seattle. Traded from New Orleans at the deadline, the speedster reunites with offensive coordinator Klint Kubiak and joins one of the NFC’s most efficient passing attacks. His downfield presence should complement Jaxon Smith-Njigba and Cooper Kupp, who remains questionable with lower-body issues.
Arizona counters with Jacoby Brissett, who continues to start in place of Kyler Murray (foot). Brissett has stabilized the offense, helping the Cardinals snap a five-game losing streak last week with a 27-17 road win over Dallas. His steady hand and decision-making have been crucial, but he faces a Seattle defense that’s dominant at home and among the league leaders in sacks.
Odds and Key Information
| Category | Details |
|---|---|
| Spread | Seahawks -6.5 (-114), Cardinals +6.5 (-106) |
| Moneyline | Seahawks -312, Cardinals +251 |
| Total (O/U) | 45.5 points |
| Venue | Lumen Field (Seattle, WA) |
| Broadcast | CBS – Sunday, November 9, 4:05 PM ET |
| Weather | Cool, overcast skies |
The market favors Seattle by nearly a touchdown, consistent with their strong home metrics and recent form. Totals hover around 45.5, signaling balanced confidence between both offensive units. Bettors should monitor line shifts on the NFL odds and scores board before kickoff.
Arizona Cardinals Outlook
The Cardinals snapped their losing streak with an efficient offensive showing in Dallas. Brissett threw for 261 yards and two touchdowns without a turnover, supported by a disciplined rushing effort led by Chris Rodriguez Jr. and Trey Benson.
Arizona’s offense ranks eighth in first downs and third-down conversions, proof of Brissett’s poise. The rushing attack remains the unit’s foundation—seventh overall in yards gained and balanced across formations. Rookie standout Marvin Harrison Jr. continues to grow as a downfield target, while tight end Trey McBride leads all team receivers in receptions and yards.
Defensively, Arizona still struggles against vertical passing, but they’ve forced timely takeaways. The absence of Kyler Murray and a depleted defensive front places added pressure on Brissett’s control of tempo.
Cardinals Injury Report
James Conner (RB) – Foot – Out
Kyler Murray (QB) – Foot – Out
Sean Murphy-Bunting (CB) – Knee – Out
Mack Wilson Sr. (LB) – Ribs – Questionable
BJ Ojulari (OLB) – Knee – Questionable
Travis Vokolek (TE) – Neck – Out
L.J. Collier (DL) – Knee – Out
For related analysis, explore how to bet on NFL games and what does the spread mean in betting.
Seattle Seahawks Outlook
Seattle has quietly evolved into one of the NFC’s most complete teams. A 38-14 demolition of Washington showcased balance: Sam Darnold threw for 330 yards and four touchdowns, and the defense forced turnovers while generating steady pressure.
Now with Rashid Shaheed joining the lineup, offensive coordinator Kubiak gains a true field-stretcher opposite Jaxon Smith-Njigba. If Cooper Kupp returns, the Seahawks could feature one of the deepest receiver rotations in football.
Seattle’s defense ranks top 10 in sacks and scoring prevention, led by Boye Mafe and Leonard Williams in the trenches. With home-field crowd noise and disciplined coverage, the Seahawks’ pass rush can dictate the pace.
Seahawks Injury Report
Cooper Kupp (WR) – Heel/Hamstring – Questionable
Jake Bobo (WR) – Achilles – Questionable
Dareke Young (WR) – Quadricep – Questionable
Julian Love (S) – Hamstring – Out
Johnathan Hankins (DT) – Back – Out
Rylie Mills (DE) – Knee – Out
Christian Haynes (G) – Pectoral – Questionable
To understand derivative markets and prop-based strategies, review alternate total points and props betting guide.
Key Matchup Table
| Key Category | Edge |
|---|---|
| Quarterback Efficiency | Seahawks |
| Wide Receiver Depth | Seahawks |
| Rushing Attack | Cardinals |
| Turnover Margin | Seahawks |
| Defensive Line | Seahawks |
| Coaching Consistency | Even |
Seattle’s advantage lies in explosive plays and red-zone efficiency. Arizona’s best chance is to sustain drives, limit possessions, and rely on Brissett’s accuracy under pressure. If the Seahawks’ secondary remains disciplined, the Cardinals’ passing ceiling shrinks considerably.
Betting Trends
- Cardinals are 4-0 ATS in their last four road games.
- Arizona is 3-0 ATS overall in its last three.
- Seahawks are 3-0 straight-up and ATS in their last three contests.
- Seattle is 7-1 SU as a favorite across its last eight regular-season games.
- Cardinals have hit the over in three of their last four games.
- Seahawks have hit the over in three consecutive home games.
Bettors can explore long-term consistency metrics and bankroll control in sports betting strategies to win big and how betting odds work.
Predictions
This NFC West clash features two efficient offenses but differing levels of depth. Seattle’s home-field advantage and Shaheed’s debut add another layer of unpredictability. Arizona has been resilient against the spread, yet Seattle’s defensive edge may determine the outcome.
Projected Score: Seahawks 24, Cardinals 20
Spread Pick: Cardinals +6.5
Total Lean: Under 45.5
For advanced insights on projected totals and futures movement, read Super Bowl odds and predictions and futures betting pros and cons.
Why You Need Expert Picks
Seattle’s improving roster depth and Arizona’s underdog fight make this a line that could swing with late injury news. Following verified handicappers through the Handicappers Leaderboard provides context beyond public sentiment.
Professional bettors focus on situational fatigue, pace, and variance to identify true value. Learn from those models via the NFL expert betting guide and maintain discipline through responsible gambling practices.
With Seattle seeking division control and Arizona gaining confidence behind Brissett, this matchup demands sharp attention—both on the field and at the window. Stay connected to ScoresAndStats for expert breakdowns and proven betting insight.


