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Washington Nationals vs Atlanta Braves Picks and Predictions April 22nd 2026
The Braves and Nationals meet again at Nationals Park on Wednesday night, with first pitch set for 6:45 p.m. ET. Atlanta comes in at 16-8, first in the NL East and 8-4 on the road, while Washington is 11-13, third in the division and just 3-8 at home. The listed TV coverage is Nationals.TV and BravesVision, and the game-time forecast looks mild, mostly clear by first pitch, with temperatures around the low 70s after earlier showers in Washington. This series is tied 1-1 after Washington hammered Atlanta 11-4 on Tuesday, snapping the Braves’ six-game winning streak. Even with that loss, Atlanta is still 7-3 over its last 10, while Washington is 5-5 over the same stretch. The bigger takeaway from
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Boston Red Sox vs New York Yankees Picks and Predictions April 22nd 2026
The Yankees and Red Sox are back at Fenway Park on Wednesday night, with first pitch set for 6:45 p.m. ET. New York comes in at 14-9, leading the AL East and riding a four-game winning streak, while Boston is 9-14, last in the division and five games back after dropping Tuesday’s opener. This is Game 2 of a three-game series, and it already feels important for Boston because the Red Sox are trying to keep this from turning into another stretch where the offense puts them in a hole early. Tuesday’s 4-0 Yankees win fit the broader trend. New York has won five of its last six, and Boston has now scored three runs or fewer in 12 of
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New York Mets vs Minnesota Twins Picks and Predictions April 22nd 2026
Minnesota heads to Citi Field on Wednesday night for the middle game of this series, with first pitch set for 7:10 p.m. ET on SNY. The Twins are 12-11 and second in the AL Central after Tuesday’s 5-3 comeback win, while the Mets have fallen to 7-16, fifth in the NL East, and are now carrying a 12-game losing streak into this matchup. That contrast is the whole handicap right now. One team has been uneven but competitive. The other keeps finding new ways to lose. The starter situation changed during the day. Minnesota is no longer listed with a TBD arm and will go with Connor Prielipp, while New York sticks with Clay Holmes. That matters because Holmes has
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Chicago Cubs vs Philadelphia Phillies Picks and Predictions April 22nd 2026
The Phillies head into Wrigley Field trying to stop a free fall. Philadelphia is 8-15, fourth in the NL East, just 2-8 over its last 10, and riding a seven-game losing streak. Chicago is moving the other direction at 14-9, second in the NL Central, 8-2 over its last 10, and on a seven-game winning streak. First pitch is set for 7:40 p.m. ET, with coverage listed on Marquee Sports Network and NBCSP+, and the weather around game time looks cool in the low 50s with light wind. That recent form matters here because the Cubs are not just squeaking by. They have a +37 run differential and have already taken the first two games of this series, winning 5-1
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Texas Rangers vs Pittsburgh Pirates Picks and Predictions April 22nd 2026
The Pirates and Rangers meet Wednesday night at Globe Life Field in Arlington, with first pitch set for 8:05 p.m. ET. Pittsburgh comes in at 13-10, fifth in the NL Central, while Texas is 12-11 and second in the AL West after opening the series with a 5-1 win on Tuesday. This is a pretty interesting early-season matchup because the records are close, the market is basically flat, and both teams have leaned on pitching more than explosive offense so far. Tuesday’s opener also gave this game a different feel. Texas held Pittsburgh to one run, got six solid innings from Kumar Rocker, and extended its home winning streak to four games, while the Pirates dropped to 5-5 on the

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Tampa Bay Rays vs. Texas Rangers Pick & Prediction APRIL 2nd 2024

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The Texas Rangers have won three of their first four games in 2024, but the defending World Series champions suffered a devastating … more

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Chicago White Sox vs. Atlanta Braves Pick & Prediction APRIL 2nd 2024

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Atlanta Braves reliever Aaron Bummer elected not to “drop names” when asked which former Chicago White Sox teammates he might want to … more

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Baltimore Orioles vs. Kansas City Royals Pick & Prediction APRIL 2nd 2024

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A pair of pitchers looking to solidify their rotation status will face off when the Kansas City Royals visit the Baltimore Orioles … more

Two Cincinnati Reds players in gray uniforms celebrate with a high five after a defensive play at second base.

Philadelphia Phillies vs. Cincinnati Reds Pick & Prediction APRIL 2nd 2024

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After back-to-back dramatic wins in their last at-bat, the Cincinnati Reds look for a third straight victory when they visit the Philadelphia … more

A Buffalo Sabres player battles for the puck along the boards.

Buffalo Sabres vs. Washington Capitals Pick & Prediction APRIL 2nd 2024

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The Washington Capitals will try to resume their playoff push when they visit the Buffalo Sabres Tuesday night. The Capitals (36-27-10, 82 … more